Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis

A Truncating Mutation of CEP135 Causes Primary Microcephaly and Disturbed Centrosomal Function

(2012) Muhammad Sajid Hussain et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polycomb group proteins in the DNA damage response: A link between radiation resistance and “stemness”

(2011) Randall S. Gieni et al.   CELL CYCLE

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

(2011) Chieh-Ju C Tang et al.   EMBO JOURNAL

Mechanisms and pathways of growth failure in primordial dwarfism

(2011) A. Klingseisen et al.   GENES & DEVELOPMENT

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

(2011) Ralph Gruber et al.   NATURE CELL BIOLOGY

Autosomal recessive primary microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum

(2011) Saqib Mahmood et al.   Orphanet Journal of Rare Diseases

Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

(2010) Julie Higgins et al.   BMC CELL BIOLOGY

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

(2010) Ismail Hassan Ismail et al.   JOURNAL OF CELL BIOLOGY

Novel CENPJ mutation causes Seckel syndrome

(2010) M. S. Al-Dosari et al.   JOURNAL OF MEDICAL GENETICS

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair

(2010) Jun Shen et al.   NATURE GENETICS

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential

(2010) Y. Ohno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice

(2010) Yulong Liang et al.   PLoS Genetics

Human RAD50 Deficiency in a Nijmegen Breakage Syndrome-like Disorder

(2009) Regina Waltes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Primary microcephaly: do all roads lead to Rome?

(2009) Gemma K. Thornton et al.   TRENDS IN GENETICS

The role of the DNA damage response pathways in brain development and microcephaly: Insight from human disorders

(2008) Mark O’Driscoll et al.   DNA REPAIR

Histone H2A ubiquitination in transcriptional regulation and DNA damage repair

(2008) Wenlai Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY