Myopathic lamin mutations impair nuclear stability in cells and tissue and disrupt nucleo-cytoskeletal coupling

LINC complexes in health and disease

(2014) Alexandre Méjat   Nucleus

Nuclear Envelope Composition Determines the Ability of Neutrophil-type Cells to Passage through Micron-scale Constrictions

(2013) Amy C. Rowat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A truncated lamin A in the Lmna−/−mouse line

(2012) Daniel Jahn et al.   Nucleus

Keeping the LINC: the importance of nucleocytoskeletal coupling in intracellular force transmission and cellular function

(2011) Maria L. Lombardi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Clinical and genetic heterogeneity in laminopathies

(2011) Anne T. Bertrand et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

LMNA variants cause cytoplasmic distribution of nuclear pore proteins in Drosophila and human muscle

(2011) George Dialynas et al.   HUMAN MOLECULAR GENETICS

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear lamins and laminopathies

(2011) Howard J. Worman   JOURNAL OF PATHOLOGY

Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans

(2011) Erin M. Bank et al.   JOURNAL OF STRUCTURAL BIOLOGY

A laminopathic mutation disrupting lamin filament assembly causes disease-like phenotypes in Caenorhabditis elegans

(2011) Erin M. Bank et al.   MOLECULAR BIOLOGY OF THE CELL

Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells

(2011) Thorsten Kolb et al.   Nucleus

The role of Drosophila Lamin C in muscle function and gene expression

(2010) G. Dialynas et al.   DEVELOPMENT

An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria

(2010) B. S. J. Davies et al.   HUMAN MOLECULAR GENETICS

Direct Synthesis of Lamin A, Bypassing Prelamin A Processing, Causes Misshapen Nuclei in Fibroblasts but No Detectable Pathology in Mice

(2010) Catherine Coffinier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin A variants that cause striated muscle disease are defective in anchoring transmembrane actin-associated nuclear lines for nuclear movement

(2010) E. S. Folker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamins

(2010) T. Dechat et al.   Cold Spring Harbor Perspectives in Biology

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes

(2009) Farhana Haque et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lamin A/C–mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy

(2009) Alexandre Méjat et al.   JOURNAL OF CELL BIOLOGY

Intermediate filaments: primary determinants of cell architecture and plasticity

(2009) Harald Herrmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuated hypertrophic response to pressure overload in a lamin A/C haploinsufficiency mouse

(2009) Mihaela Cupesi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Induction of a Massive Endoplasmic Reticulum and Perinuclear Space Expansion by Expression of Lamin B Receptor Mutants and the Related Sterol Reductases TM7SF2 and DHCR7

(2009) Monika Zwerger et al.   MOLECULAR BIOLOGY OF THE CELL

A Comparative Study of Drosophila and Human A-Type Lamins

(2009) Sandra R. Schulze et al.   PLoS One

Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization

(2009) K. J. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Supramolecular Organization of the C. elegans Nuclear Lamin Filament

(2008) Kfir Ben-Harush et al.   JOURNAL OF MOLECULAR BIOLOGY

HGPS and related premature aging disorders: From genomic identification to the first therapeutic approaches

(2008) Sandrine Pereira et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

(2008) Paola Scaffidi et al.   NATURE CELL BIOLOGY

Nuclear changes in skeletal muscle extend to satellite cells in autosomal dominant Emery-Dreifuss muscular dystrophy/limb-girdle muscular dystrophy 1B

(2008) Young-Eun Park et al.   NEUROMUSCULAR DISORDERS