Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

(2012) Niall S. Kenneth et al.   BIOCHEMICAL JOURNAL

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

Caspase-11 Promotes the Fusion of Phagosomes Harboring Pathogenic Bacteria with Lysosomes by Modulating Actin Polymerization

(2012) Anwari Akhter et al.   IMMUNITY

Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors

(2012) Stephen T. Smale   IMMUNOLOGICAL REVIEWS

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism

(2012) Nadine Bakkar et al.   JOURNAL OF CELL BIOLOGY

HIV-1 Proteins Preferentially Activate Anti-Inflammatory M2-Type Macrophages

(2012) T. Chihara et al.   JOURNAL OF IMMUNOLOGY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Rescue of Dystrophic Skeletal Muscle by PGC-1α Involves a Fast to Slow Fiber Type Shift in the mdx Mouse

(2012) Joshua T. Selsby et al.   PLoS One

Impaired Adaptive Response to Mechanical Overloading in Dystrophic Skeletal Muscle

(2012) Pierre Joanne et al.   PLoS One

TWEAK and cIAP1 Regulate Myoblast Fusion Through the Noncanonical NF- B Signaling Pathway

(2012) E. K. Enwere et al.   Science Signaling

Cellular Inhibitors of Apoptosis Are Global Regulators of NF- B and MAPK Activation by Members of the TNF Family of Receptors

(2012) E. Varfolomeev et al.   Science Signaling

Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

(2011) V. Ljubicic et al.   HUMAN MOLECULAR GENETICS

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Systemic delivery of NEMO binding domain/IKKγ inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology

(2011) Daniel P. Reay et al.   NEUROBIOLOGY OF DISEASE

Soleus muscle in glycosylation-deficient muscular dystrophy is protected from contraction-induced injury

(2010) Jessica D. Gumerson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Differential expression of myosin heavy chain isoforms in the masticatory muscles of dystrophin-deficient mice

(2010) A. Spassov et al.   EUROPEAN JOURNAL OF ORTHODONTICS

MAP kinase phosphatase-1 deficiency impairs skeletal muscle regeneration and exacerbates muscular dystrophy

(2010) Hao Shi et al.   FASEB JOURNAL

Smac Mimetic Compounds Potentiate Interleukin-1β-mediated Cell Death

(2010) Herman H. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Smac mimetics: implications for enhancement of targeted therapies in leukemia

(2010) E Weisberg et al.   LEUKEMIA

TNF Inhibits Notch-1 in Skeletal Muscle Cells by Ezh2 and DNA Methylation Mediated Repression: Implications in Duchenne Muscular Dystrophy

(2010) Swarnali Acharyya et al.   PLoS One

Making Fast-Twitch Dystrophic Muscles Bigger Protects Them from Contraction Injury and Attenuates the Dystrophic Pathology

(2009) Stefan M. Gehrig et al.   AMERICAN JOURNAL OF PATHOLOGY

Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

(2009) Mathieu J.M. Bertrand et al.   IMMUNITY

Preclinical drug trials in themdxmouse: Assessment of reliable and sensitive outcome measures

(2009) Christopher F. Spurney et al.   MUSCLE & NERVE

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

(2009) J. E. Rooney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

(2008) James E. Vince et al.   JOURNAL OF CELL BIOLOGY

IKK/NF-κB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis

(2008) Nadine Bakkar et al.   JOURNAL OF CELL BIOLOGY

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY

Both cIAP1 and cIAP2 regulate TNF -mediated NF- B activation

(2008) D. J. Mahoney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA