Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf–Hirschhorn syndrome

Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome

(2011) Louise S Bicknell et al.   NATURE GENETICS

Replication stress, a source of epigenetic aberrations in cancer?

(2010) Zuzana Jasencakova et al.   BIOESSAYS

Telomere healing following DNA polymerase arrest-induced breakages is likely the main mechanism generating chromosome 4p terminal deletions

(2010) Femke Hannes et al.   HUMAN MUTATION

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

(2010) Zuzana Jasencakova et al.   MOLECULAR CELL

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

The program for processing newly synthesized histones H3.1 and H4

(2010) Eric I Campos et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Keeping it simple: what mouse models of Wolf-Hirschhorn syndrome can tell us about large chromosomal deletions

(2009) J. M. Abrams et al.   Disease Models & Mechanisms

Mouse models for ATR deficiency

(2009) Mark O’Driscoll   DNA REPAIR

Cellular dynamics of the negative transcription elongation factor NELF

(2009) Tetsu M.C. Yung et al.   EXPERIMENTAL CELL RESEARCH

A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome

(2009) Angus G. McQuibban et al.   HUMAN MOLECULAR GENETICS

The Target of the NSD Family of Histone Lysine Methyltransferases Depends on the Nature of the Substrate

(2009) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Negative Elongation Factor Activates Transcription and Regulates Alternative Transcription Initiation

(2009) Jianlong Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome

(2009) Keisuke Nimura et al.   NATURE

Knockdown of SLBP results in nuclear retention of histone mRNA

(2009) K. D. Sullivan et al.   RNA

Restoring chromatin after replication: How new and old histone marks come together

(2009) Zuzana Jasencakova et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

On the nosology and pathogenesis of Wolf-Hirschhorn syndrome: Genotype-phenotype correlation analysis of 80 patients and literature review

(2008) Marcella Zollino et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Mouse models of Wolf-Hirschhorn syndrome

(2008) Ruth Simon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Pathogenic significance of deletions distal to the currently described Wolf-Hirschhorn syndrome critical regions on 4p16.3

(2008) Sarah T. South et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Update on the clinical features and natural history of Wolf-Hirschhorn (4p-) syndrome: Experience with 87 patients and recommendations for routine health supervision

(2008) Agatino Battaglia et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

The role of the DNA damage response pathways in brain development and microcephaly: Insight from human disorders

(2008) Mark O’Driscoll et al.   DNA REPAIR

NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly

(2008) D. A. Gilchrist et al.   GENES & DEVELOPMENT

MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

(2008) J. L.R. Brito et al.   HAEMATOLOGICA

Multiple Myeloma-Related WHSC1/MMSET Isoform RE-IIBP Is a Histone Methyltransferase with Transcriptional Repression Activity

(2008) J.-Y. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

(2008) William F. Marzluff et al.   NATURE REVIEWS GENETICS

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

(2007) J. Marango et al.   BLOOD