Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1

ATM and the Molecular Pathogenesis of Ataxia Telangiectasia

(2011) Peter J. McKinnon   Annual Review of Pathology-Mechanisms of Disease

Mechanisms Limiting Body Growth in Mammals

(2011) Julian C. Lui et al.   ENDOCRINE REVIEWS

Mechanisms and pathways of growth failure in primordial dwarfism

(2011) A. Klingseisen et al.   GENES & DEVELOPMENT

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR

(2011) Philip M Reaper et al.   Nature Chemical Biology

Novel CENPJ mutation causes Seckel syndrome

(2010) M. S. Al-Dosari et al.   JOURNAL OF MEDICAL GENETICS

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

(2010) Ersan Kalay et al.   NATURE GENETICS

DNA Distress: Just Ring 9-1-1

(2009) Michael Kemp et al.   CURRENT BIOLOGY

Mouse models for ATR deficiency

(2009) Mark O’Driscoll   DNA REPAIR

A tale of two tails: Activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1

(2009) Vasundhara M. Navadgi-Patil et al.   DNA REPAIR

Growth hormone supplementation increased latency to tumourigenesis inAtm-deficient mice

(2009) Ralf Schubert et al.   GROWTH FACTORS

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

(2009) Matilde Murga et al.   NATURE GENETICS

Dual inactivation of Hus1 and p53 in the mouse mammary gland results in accumulation of damaged cells and impaired tissue regeneration

(2009) Stephanie A. Yazinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haploinsufficiency of DNA Damage Response Genes and their Potential Influence in Human Genomic Disorders

(2008) Mark O'Driscoll   CURRENT GENOMICS

Tissue-specific accelerated aging in nucleotide excision repair deficiency

(2008) Laura J. Niedernhofer   MECHANISMS OF AGEING AND DEVELOPMENT

Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function

(2008) Natalie C Jones et al.   NATURE MEDICINE

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism

(2008) A. Rauch et al.   SCIENCE