Pharmacogenomics of adverse drug reactions: implementing personalized medicine

The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

(2012) R A Wilke et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Direct interaction between HLA-B and carbamazepine activates T cells in patients with Stevens-Johnson syndrome

(2012) Chun-Yu Wei et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Statins Personalized

(2012) H. Robert Superko et al.   MEDICAL CLINICS OF NORTH AMERICA

Clinical utility of pharmacogenetic biomarkers in cardiovascular therapeutics: a challenge for clinical implementation

(2012) Frank S Ong et al.   PHARMACOGENOMICS

Pharmacogenetics and pharmacogenomics: role of mutational analysis in anti-cancer targeted therapy

(2012) A Savonarola et al.   PHARMACOGENOMICS JOURNAL

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

(2011) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

(2011) M. Isabel Lucena et al.   GASTROENTEROLOGY

HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans

(2011) Mark McCormack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic involvement in statins induced myopathy. Preliminary data from an observational case–control study

(2010) Luca Puccetti et al.   ATHEROSCLEROSIS

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

(2010) N. A. Limdi et al.   BLOOD

Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI

(2010) Jessica L. Mega et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury

(2010) Jonathan B Singer et al.   NATURE GENETICS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

HLA-B*5901is strongly associated with methazolamide-induced Stevens–Johnson syndrome/toxic epidermal necrolysis

(2010) Sae-Hoon Kim et al.   PHARMACOGENOMICS

The SLCO1B1*5Genetic Variant Is Associated With Statin-Induced Side Effects

(2009) Deepak Voora et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

(2009) Ann K Daly et al.   NATURE GENETICS

Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data

(2009)   NEW ENGLAND JOURNAL OF MEDICINE

HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients

(2009) Soranun Chantarangsu et al.   Pharmacogenetics and Genomics

APOE gene polymorphisms and response to statin therapy

(2009) E Zintzaras et al.   PHARMACOGENOMICS JOURNAL

A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose

(2009) Fumihiko Takeuchi et al.   PLoS Genetics

Integration and use of biomarkers in drug development, regulation and clinical practice: a US regulatory perspective

(2008) Shashi Amur et al.   Biomarkers in Medicine

A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose

(2008) G. M. Cooper et al.   BLOOD

Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response

(2008) Deepak Voora et al.   Circulation-Cardiovascular Genetics

Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population

(2008) Chaichon Locharernkul et al.   EPILEPSIA

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

A European study of HLA-B in Stevens???Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

(2008) Christine Lonjou et al.   Pharmacogenetics and Genomics

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease

(2008) Tuomo Nieminen et al.   PHARMACOGENOMICS

HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens–Johnson syndrome and toxic epidermal necrolysis

(2008) Nahoko Kaniwa et al.   PHARMACOGENOMICS