Survival of pancreatic beta cells is partly controlled by a TCF7L2-p53-p53INP1-dependent pathway

Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells

(2011) Orkhontuya Tsedensodnom et al.   EXPERIMENTAL CELL RESEARCH

TCF7L2 splice variants have distinct effects on β-cell turnover and function

(2011) Olivier Le Bacquer et al.   HUMAN MOLECULAR GENETICS

Phosphorylation of TCF Proteins by Homeodomain-interacting Protein Kinase 2

(2011) Hiroki Hikasa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diabetes Genes and Prostate Cancer in the Atherosclerosis Risk in Communities Study

(2010) T. E. Meyer et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

(2010) Michael L. Stitzel et al.   Cell Metabolism

Molecular Function of TCF7L2: Consequences of TCF7L2 Splicing for Molecular Function and Risk for Type 2 Diabetes

(2010) Ola Hansson et al.   Current Diabetes Reports

Disease-associated loci are significantly over-represented among genes bound by transcription factor 7-like 2 (TCF7L2) in vivo

(2010) J. Zhao et al.   DIABETOLOGIA

A map of open chromatin in human pancreatic islets

(2010) Kyle J Gaulton et al.   NATURE GENETICS

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

(2010) Andreas Weise et al.   NUCLEIC ACIDS RESEARCH

Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors

(2010) Clare L. Kirkpatrick et al.   PLoS One

Diabetes and Cancer

(2010) T. A. Chowdhury   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action

(2009) D. T. Villareal et al.   DIABETES

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet  -Cells

(2009) G. da Silva Xavier et al.   DIABETES

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets

(2009) P. Osmark et al.   DIABETOLOGIA

Tissue-specific alternative splicing of TCF7L2

(2009) Ludmila Prokunina-Olsson et al.   HUMAN MOLECULAR GENETICS

Apoptotic, Regenerative, And Immune-Related Signaling in Human Islets from Type 2 Diabetes Individuals

(2009) Hanna K. Nyblom et al.   JOURNAL OF PROTEOME RESEARCH

HNF1B and JAZF1 genes, diabetes, and prostate cancer risk

(2009) Victoria L. Stevens et al.   PROSTATE

Akt and PTEN: β-cell mass and pancreas plasticity

(2009) Lynda Elghazi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

TCF7L2 controls insulin gene expression and insulin secretion in mature pancreatic β-cells

(2008) Merewyn K. Loder et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Transcription Factor 7-like 2 Polymorphism and Colon Cancer

(2008) M. L. Slattery et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The WNT signalling pathway and diabetes mellitus

(2008) T. Jin   DIABETOLOGIA

Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation

(2008) Zhengyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-Wide Pattern of TCF7L2/TCF4 Chromatin Occupancy in Colorectal Cancer Cells

(2008) P. Hatzis et al.   MOLECULAR AND CELLULAR BIOLOGY

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

Minireview: The Wnt Signaling Pathway Effector TCF7L2 and Type 2 Diabetes Mellitus

(2008) Tianru Jin et al.   MOLECULAR ENDOCRINOLOGY

Clinical Risk Factors, DNA Variants, and the Development of Type 2 Diabetes

(2008) Valeriya Lyssenko et al.   NEW ENGLAND JOURNAL OF MEDICINE