Perturbation of U2AF65/NXF1-mediated RNA nuclear export enhances RNA toxicity in polyQ diseases

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1

(2011) Wing Man Chan et al.   HUMAN MOLECULAR GENETICS

Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference

(2011) Mateusz de Mezer et al.   NUCLEIC ACIDS RESEARCH

Long Tract of Untranslated CAG Repeats Is Deleterious in Transgenic Mice

(2011) Ren-Jun Hsu et al.   PLoS One

Muscleblind participates in RNA toxicity of expanded CAG and CUG repeats in Caenorhabditis elegans

(2010) Li-Chun Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

(2010) Chantal Sellier et al.   EMBO JOURNAL

Roles of trinucleotide-repeat RNA in neurological disease and degeneration

(2010) Ling-Bo Li et al.   TRENDS IN NEUROSCIENCES

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

Bridging the gap: From protein misfolding to protein misfolding diseases

(2009) Leila M. Luheshi et al.   FEBS LETTERS

mRNA nuclear export at a glance

(2009) S. R. Carmody et al.   JOURNAL OF CELL SCIENCE

Human receptor for activated protein kinase C1 associates with polyglutamine aggregates and modulates polyglutamine toxicity

(2008) Wun Lam et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sodium dodecyl sulfate-insoluble oligomers are involved in polyglutamine degeneration

(2008) S. L. Alan Wong et al.   FASEB JOURNAL

RNA toxicity is a component of ataxin-3 degeneration in Drosophila

(2008) Ling-Bo Li et al.   NATURE

Polyglutamine neurodegeneration: protein misfolding revisited

(2008) Aislinn J. Williams et al.   TRENDS IN NEUROSCIENCES