Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C

Relationship between polymorphisms of the inosine triphosphatase gene and anaemia or outcome after treatment with pegylated interferon and ribavirin

(2011) Masayuki Kurosaki et al.   ANTIVIRAL THERAPY

Inosine Triphosphate Protects Against Ribavirin-Induced Adenosine Triphosphate Loss by Adenylosuccinate Synthase Function

(2011) Yuki Hitomi et al.   GASTROENTEROLOGY

ITPA Polymorphism Affects Ribavirin-Induced Anemia and Outcomes of Therapy—A Genome-Wide Study of Japanese HCV Virus Patients

(2010) Hidenori Ochi et al.   GASTROENTEROLOGY

Hepatitis C pharmacogenetics: State of the art in 2010

(2010) Nezam H. Afdhal et al.   HEPATOLOGY

Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan

(2010) Hiromitsu Kumada et al.   HEPATOLOGY RESEARCH

λ-Interferons and the single nucleotide polymorphisms: A milestone to tailor-made therapy for chronic hepatitis C

(2010) Yasuhito Tanaka et al.   HEPATOLOGY RESEARCH

ITPA gene variant protects against anemia induced by pegylated interferon-α and ribavirin therapy for Japanese patients with chronic hepatitis C

(2010) Naoya Sakamoto et al.   HEPATOLOGY RESEARCH

A Novel C53/LZAP-interacting Protein Regulates Stability of C53/LZAP and DDRGK Domain-containing Protein 1 (DDRGK1) and Modulates NF-κB Signaling

(2010) Jianchun Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C

(2010) Jacques Fellay et al.   NATURE

Rapid loss of hepatitis C virus genotype 1b from serum in patients receiving a triple treatment with telaprevir (MP-424), pegylated interferon and ribavirin for 12 weeks

(2009) Fumitaka Suzuki et al.   HEPATOLOGY RESEARCH

An Open Pilot Study Exploring the Efficacy of Fluvastatin, Pegylated Interferon and Ribavirin in Patients with Hepatitis C Virus Genotype 1b in High Viral Loads

(2009) Hitomi Sezaki et al.   INTERVIROLOGY

New therapeutic approaches to hepatitis C virus

(2009) Naoya Sakamoto et al.   JOURNAL OF GASTROENTEROLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Telaprevir and Peginterferon with or without Ribavirin for Chronic HCV Infection

(2009) Christophe Hézode et al.   NEW ENGLAND JOURNAL OF MEDICINE

Telaprevir with Peginterferon and Ribavirin for Chronic HCV Genotype 1 Infection

(2009) John G. McHutchison et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical, virologic, histologic, and biochemical outcomes after successful HCV therapy: A 5-year follow-up of 150 patients

(2008) Sarah L. George et al.   HEPATOLOGY

Thrombocytopenia associated with chronic liver disease

(2008) Nezam Afdhal et al.   JOURNAL OF HEPATOLOGY