Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signaling

(2009) Rudolf Fuchshofer et al.   EXPERIMENTAL EYE RESEARCH

The ataxia protein sacsin is a functional co-chaperone that protects against polyglutamine-expanded ataxin-1

(2009) David A. Parfitt et al.   HUMAN MOLECULAR GENETICS

siah-1 Protein Is Necessary for High Glucose-induced Glyceraldehyde-3-phosphate Dehydrogenase Nuclear Accumulation and Cell Death in Müller Cells

(2009) E. Chepchumba K. Yego et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of cellular networks on disease comorbidity

(2009) Juyong Park et al.   Molecular Systems Biology

Dynamic modularity in protein interaction networks predicts breast cancer outcome

(2009) Ian W Taylor et al.   NATURE BIOTECHNOLOGY

Genetic address book for retinal cell types

(2009) Sandra Siegert et al.   NATURE NEUROSCIENCE

Loss of yata, a Novel Gene Regulating the Subcellular Localization of APPL, Induces Deterioration of Neural Tissues and Lifespan Shortening

(2009) Masaki Sone et al.   PLoS One

A Dynamic Network Approach for the Study of Human Phenotypes

(2009) César A. Hidalgo et al.   PLoS Computational Biology

Motor coordination defects in mice deficient for the Sam68 RNA-binding protein

(2008) Kiven E. Lukong et al.   BEHAVIOURAL BRAIN RESEARCH

The art of community detection

(2008) Natali Gulbahce et al.   BIOESSAYS

Align human interactome with phenome to identify causative genes and networks underlying disease families

(2008) Xuebing Wu et al.   BIOINFORMATICS

A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis

(2008) Mike Boxem et al.   CELL

Atrophins’ emerging roles in development and neurodegenerative disease

(2008) Y. Shen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration

(2008) Gwenn A. Garden et al.   CEREBELLUM

Altered expression of HSPA5, HSPA8 and PARK7 in spinocerebellar ataxia type 17 identified by 2-dimensional fluorescence difference in gel electrophoresis

(2008) Li-Ching Lee et al.   CLINICA CHIMICA ACTA

Protein networks in disease

(2008) T. Ideker et al.   GENOME RESEARCH

Androgen receptor knockout and knock-in mouse models

(2008) S Kerkhofs et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

THG-1pit moves to nucleus at the onset of cerebellar granule neurons apoptosis

(2008) Sonia Canterini et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

(2008) Janghoo Lim et al.   NATURE

Deletion of Mecp2 in Sim1-Expressing Neurons Reveals a Critical Role for MeCP2 in Feeding Behavior, Aggression, and the Response to Stress

(2008) Sharyl L. Fyffe et al.   NEURON

High-Quality Binary Protein Interaction Map of the Yeast Interactome Network

(2008) H. Yu et al.   SCIENCE