The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease
出版年份 2013 全文链接
标题
The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease
作者
关键词
Disease Penetrance, Cybrid Cell, Mitochondrial Malfunction, Haplogroup Background, Spindle Transfer
出版物
HUMAN GENETICS
Volume 133, Issue 4, Pages 435-458
出版商
Springer Nature
发表日期
2013-12-03
DOI
10.1007/s00439-013-1402-4
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- A novel diagnostic tool reveals mitochondrial pathology in human diseases and aging
- (2016) Morten Scheibye-Knudsen et al. Aging-US
- Mitochondrial Depletion Syndromes in Children and Adults
- (2014) Josef Finsterer et al. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
- Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts
- (2013) Chad Lerner et al. AGING CELL
- Mutations in FBXL4 Cause Mitochondrial Encephalopathy and a Disorder of Mitochondrial DNA Maintenance
- (2013) Penelope E. Bonnen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Severe infantile leigh syndrome associated with a rare mitochondrialND6mutation, m.14487T>C
- (2013) Mark Tarnopolsky et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Changes of mitochondria in atherosclerosis: Possible determinant in the pathogenesis of the disease
- (2013) Igor A. Sobenin et al. ATHEROSCLEROSIS
- Defective quality control mechanisms and accumulation of damaged mitochondria link Gaucher and Parkinson diseases
- (2013) Laura D Osellame et al. Autophagy
- Changes of haematic parameters, redox status and mitochondrial complex activity in the heart and liver of broilers fed with different density diets under low ambient temperature
- (2013) Y. Z. Peng et al. AVIAN PATHOLOGY
- Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload
- (2013) Jessica L. Fetterman et al. BIOCHEMICAL JOURNAL
- Mitochondrial quality control in neurodegenerative diseases
- (2013) Luc Dupuis BIOCHIMIE
- Association of decreased mitochondrial DNA content with the progression of colorectal cancer
- (2013) HaiHong Cui et al. BMC CANCER
- Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study
- (2013) M Cristina Kenney et al. BMC Medical Genetics
- Association of mitochondrial DNA copy number in peripheral blood leukocytes with risk of esophageal adenocarcinoma
- (2013) E. Xu et al. CARCINOGENESIS
- Calcium release microdomains and mitochondria
- (2013) Michael Kohlhaas et al. CARDIOVASCULAR RESEARCH
- The regulation of mitochondrial DNA copy number in glioblastoma cells
- (2013) A Dickinson et al. CELL DEATH AND DIFFERENTIATION
- Hereditary mtDNA Heteroplasmy: A Baseline for Aging?
- (2013) Michael Keogh et al. Cell Metabolism
- Mitochondrial Dysfunction Indirectly Elevates ROS Production by the Endoplasmic Reticulum
- (2013) Michael P. Murphy Cell Metabolism
- Epigenetic Silencing Mediates Mitochondria Stress-Induced Longevity
- (2013) Elizabeth A. Schroeder et al. Cell Metabolism
- The mitochondrial genome encodes abundant small noncoding RNAs
- (2013) Seungil Ro et al. CELL RESEARCH
- Mitochondrial DNA Damage Can Promote Atherosclerosis Independently of Reactive Oxygen Species Through Effects on Smooth Muscle Cells and Monocytes and Correlates With Higher-Risk Plaques in Humans
- (2013) Emma Yu et al. CIRCULATION
- Uncoupling Protein 2 Impacts Endothelial Phenotype via p53-Mediated Control of Mitochondrial Dynamics
- (2013) Yukio Shimasaki et al. CIRCULATION RESEARCH
- From evolutionary bystander to master manipulator: the emerging roles for the mitochondrial genome as a modulator of nuclear gene expression
- (2013) Martin P Horan et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Clinical, biochemical, cellular and molecular characterization of mitochondrial DNA depletion syndrome due to novel mutations in the MPV17 gene
- (2013) Johanna Uusimaa et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Oxidative stress response elicited by mitochondrial dysfunction: Implication in the pathophysiology of aging
- (2013) Chih-Hao Wang et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Mitochondrial-related gene expression profiles suggest an important role of PGC-1alpha in the compensatory mechanism of endemic dilated cardiomyopathy
- (2013) Shu-Lan He et al. EXPERIMENTAL CELL RESEARCH
- Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells
- (2013) Bo Wang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial Gene Polymorphisms That Protect Mice From Colitis
- (2013) Florian Bär et al. GASTROENTEROLOGY
- The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease
- (2013) Li Zuo et al. GENE
- Mitochondrial–Nuclear Interactions: Compensatory Evolution or Variable Functional Constraint among Vertebrate Oxidative Phosphorylation Genes?
- (2013) Feifei Zhang et al. Genome Biology and Evolution
- Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool
- (2013) Xiao Wang et al. HUMAN MOLECULAR GENETICS
- Mutation dependance of the mitochondrial DNA copy number in the first stages of human embryogenesis
- (2013) Sophie Monnot et al. HUMAN MOLECULAR GENETICS
- A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin
- (2013) Maria Damiano et al. HUMAN MOLECULAR GENETICS
- Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation
- (2013) Yu-Chin Su et al. HUMAN MOLECULAR GENETICS
- Mitochondrial dysfunction and sarcopenia of aging: From signaling pathways to clinical trials
- (2013) Emanuele Marzetti et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Exploring the Role of Genetic Variability and Lifestyle in Oxidative Stress Response for Healthy Aging and Longevity
- (2013) Serena Dato et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Induction of a Tumor-associated Activating Mutation in Protein Tyrosine PhosphatasePtpn11(Shp2) Enhances Mitochondrial Metabolism, Leading to Oxidative Stress and Senescence
- (2013) Hong Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria-derived Hydrogen Peroxide Selectively Enhances T Cell Receptor-initiated Signal Transduction
- (2013) Tejpal Gill et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A mitochondrial bioenergetic etiology of disease
- (2013) Douglas C. Wallace JOURNAL OF CLINICAL INVESTIGATION
- The role of mitochondria in aging
- (2013) Ana Bratic et al. JOURNAL OF CLINICAL INVESTIGATION
- Amelioration of neurodegenerative diseases by cell death-induced cytoplasmic delivery of humanin
- (2013) Tae-Yoon Park et al. JOURNAL OF CONTROLLED RELEASE
- Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers
- (2013) Xinyuan Li et al. Journal of Hematology & Oncology
- Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase
- (2013) Martin Patrick Horan et al. JOURNAL OF HUMAN GENETICS
- Prevalence of rare mitochondrial DNA mutations in mitochondrial disorders
- (2013) Sylvie Bannwarth et al. JOURNAL OF MEDICAL GENETICS
- Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells
- (2013) Hye Jin Jung et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Reduced Mitochondrial DNA Content and Heterozygous Nuclear Gene Mutations in Patients With Acute Liver Failure
- (2013) Daniel Helbling et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- Identification of mitochondrial dysfunction in Hutchinson–Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture
- (2013) José Rivera-Torres et al. Journal of Proteomics
- Mitochondria and Tumor Progression in Ulcerative Colitis
- (2013) Cigdem Himmetoglu Ussakli et al. JNCI-Journal of the National Cancer Institute
- Behavioral and metabolic characterization of heterozygous and homozygous POLG mutator mice
- (2013) Ying Dai et al. MITOCHONDRION
- Study of insulin resistance in cybrid cells harboring diabetes-susceptible and diabetes-protective mitochondrial haplogroups
- (2013) Shao-Wen Weng et al. MITOCHONDRION
- Mitochondrial DNA haplogroup H as a risk factor for idiopathic dilated cardiomyopathy in Spanish population
- (2013) M. Fernández-Caggiano et al. MITOCHONDRION
- Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype
- (2013) Gaku Takibuchi et al. MITOCHONDRION
- Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics
- (2013) Manti Guha et al. MITOCHONDRION
- Mitochondrial DNA variation analysis in cervical cancer
- (2013) Shama Prasada Kabekkodu et al. MITOCHONDRION
- Mitochondrial function and insulin secretion
- (2013) Pierre Maechler MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression
- (2013) Emily N Cronin-Furman et al. Molecular Neurodegeneration
- Mutations that affect mitochondrial functions and their association with neurodegenerative diseases
- (2013) Varinderpal S. Dhillon et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Germline mitochondrial DNA mutations aggravate ageing and can impair brain development
- (2013) Jaime M. Ross et al. NATURE
- Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease
- (2013) Cornelia Kornblum et al. NATURE GENETICS
- The clinical maze of mitochondrial neurology
- (2013) Salvatore DiMauro et al. Nature Reviews Neurology
- Mitochondrial DNA Depletion Syndromes: Review and Updates of Genetic Basis, Manifestations, and Therapeutic Options
- (2013) Ayman W. El-Hattab et al. Neurotherapeutics
- Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation
- (2013) Christopher A. Koczor et al. PHYSIOLOGICAL GENOMICS
- Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration
- (2013) M. Cristina Kenney et al. PLoS One
- Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin
- (2013) Youngnam N. Jin et al. PLoS One
- Mitochondrial DNA Copy Number and Risk of Oral Cancer: A Report from Northeast India
- (2013) Rosy Mondal et al. PLoS One
- Mitochondrial DNA Mutations in Mutator Mice Confer Respiration Defects and B-Cell Lymphoma Development
- (2013) Takayuki Mito et al. PLoS One
- Mitochondrial Telomerase Protects Cancer Cells from Nuclear DNA Damage and Apoptosis
- (2013) Chatchawan Singhapol et al. PLoS One
- Crosstalk from Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways
- (2013) Benny Abraham Kaipparettu et al. PLoS One
- Mitochondrial DNA Copy Number Is Associated with Breast Cancer Risk
- (2013) Bharat Thyagarajan et al. PLoS One
- Dysregulation of Mitochondrial Quality Control Processes Contribute to Sarcopenia in a Mouse Model of Premature Aging
- (2013) Anna-Maria Joseph et al. PLoS One
- The Polymorphic AluYb8 Insertion in the MUTYH Gene is Associated with Reduced Type 1 Protein Expression and Reduced Mitochondrial DNA Content
- (2013) Wenwen Guo et al. PLoS One
- Mitochondrial Haplogroups Modify the Risk of Developing Hypertrophic Cardiomyopathy in a Danish Population
- (2013) Christian M. Hagen et al. PLoS One
- The Plasma Mitochondrial DNA Is an Independent Predictor for Post-Traumatic Systemic Inflammatory Response Syndrome
- (2013) Xiaoling Gu et al. PLoS One
- Mitochondrial Inverted Repeats Strongly Correlate with Lifespan: mtDNA Inversions and Aging
- (2013) Jiang-Nan Yang et al. PLoS One
- Mitochondrial Haplotypes Associated with Biomarkers for Alzheimer’s Disease
- (2013) Perry G. Ridge et al. PLoS One
- Structural Analysis of Mitochondrial Mutations Reveals a Role for Bigenomic Protein Interactions in Human Disease
- (2013) Rhiannon E. Lloyd et al. PLoS One
- Frequency and Pattern of Heteroplasmy in the Complete Human Mitochondrial Genome
- (2013) Amanda Ramos et al. PLoS One
- Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup
- (2013) Kevin A. Strauss et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Systems Approach for Decoding Mitochondrial Retrograde Signaling Pathways
- (2013) S. Chae et al. Science Signaling
- Mitochondrial DNA Haplotypes Define Gene Expression Patterns in Pluripotent and Differentiating Embryonic Stem Cells
- (2013) Richard D.W. Kelly et al. STEM CELLS
- Humanin: a harbinger of mitochondrial-derived peptides?
- (2013) Changhan Lee et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease
- (2013) D. C. Wallace et al. Cold Spring Harbor Perspectives in Biology
- Mitochondrial DNA damage induces apoptosis in senescent cells
- (2013) R-M Laberge et al. Cell Death & Disease
- Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage
- (2013) Scott R. Kennedy et al. PLoS Genetics
- Associations of Mitochondrial Haplogroups B4 and E with Biliary Atresia and Differential Susceptibility to Hydrophobic Bile Acid
- (2013) Mao-Meng Tiao et al. PLoS Genetics
- Haplogroup T Is an Obesity Risk Factor: Mitochondrial DNA Haplotyping in a Morbid Obese Population from Southern Italy
- (2013) Carmela Nardelli et al. Biomed Research International
- Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging
- (2013) Jenny K. Ngo et al. Redox Biology
- Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts
- (2013) Nady Braidy et al. Translational Neurodegeneration
- Circulating humanin levels are associated with preserved coronary endothelial function
- (2012) R. J. Widmer et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Construction of two novel reciprocal conplastic rat strains and characterization of cardiac mitochondria
- (2012) Sivarajan Kumarasamy et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- AMPK and GCN2–ATF4 signal the repression of mitochondria in colon cancer cells
- (2012) Inmaculada Martínez-Reyes et al. BIOCHEMICAL JOURNAL
- Oxidative phosphorylation differences between mitochondrial DNA haplogroups modify the risk of Leber's hereditary optic neuropathy
- (2012) Aurora Gómez-Durán et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- What is influencing the phenotype of the common homozygous polymerase-γ mutation p.Ala467Thr?
- (2012) Vivienne C. M. Neeve et al. BRAIN
- Adults with RRM2B-related mitochondrial disease have distinct clinical and molecular characteristics
- (2012) Robert D. S. Pitceathly et al. BRAIN
- Mitochondrial Copy Number is Associated with Colorectal Cancer Risk
- (2012) B. Thyagarajan et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer
- (2012) Jian Hu et al. CELL
- Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness
- (2012) Nuno Raimundo et al. CELL
- Mitochondrial regulation of epigenetics and its role in human diseases
- (2012) Sheroy Minocherhomji et al. Epigenetics
- Charcot-Marie-Tooth hereditary neuropathy due to a mitochondrial ATP6 mutation
- (2012) Matthis Synofzik et al. EUROPEAN JOURNAL OF NEUROLOGY
- Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease
- (2012) Michael H. Yan et al. FREE RADICAL BIOLOGY AND MEDICINE
- A novel mitochondrial mutation m.8989G>C associated with neuropathy, ataxia, retinitis pigmentosa — The NARP syndrome
- (2012) Morten Duno et al. GENE
- A role for mitochondria in gestational diabetes mellitus?
- (2012) Francesca Crovetto et al. GYNECOLOGICAL ENDOCRINOLOGY
- Novel mitochondrial DNA mutations responsible for maternally inherited nonsyndromic hearing loss
- (2012) Nicolás Gutiérrez Cortés et al. HUMAN MUTATION
- Role of Mitochondrial Translocation of Telomerase in Hepatocellular Carcinoma Cells with Multidrug Resistance
- (2012) Xianlong Ling et al. International Journal of Medical Sciences
- Mitochondrial dysfunction and cancer metastasis
- (2012) Emily I. Chen JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- The Amerindian mtDNA haplogroup B2 enhances the risk of HPV for cervical cancer: de-regulation of mitochondrial genes may be involved
- (2012) Mariano Guardado-Estrada et al. JOURNAL OF HUMAN GENETICS
- Impaired mitochondrial respiration and decreased fatigue resistance followed by severe muscle weakness in skeletal muscle of mitochondrial DNA mutator mice
- (2012) Takashi Yamada et al. JOURNAL OF PHYSIOLOGY-LONDON
- Clinical and molecular characterization of a Han Chinese family with high penetrance of essential hypertension
- (2012) Lili Teng et al. Mitochondrial DNA
- The Mitochondrial ATPase Inhibitory Factor 1 Triggers a ROS-Mediated Retrograde Prosurvival and Proliferative Response
- (2012) Laura Formentini et al. MOLECULAR CELL
- Mitochondrial Localization of Telomeric Protein TIN2 Links Telomere Regulation to Metabolic Control
- (2012) Liuh-Yow Chen et al. MOLECULAR CELL
- A new phenotype of brain iron accumulation with dystonia, optic atrophy, and peripheral neuropathy
- (2012) Rita Horvath et al. MOVEMENT DISORDERS
- Towards germline gene therapy of inherited mitochondrial diseases
- (2012) Masahito Tachibana et al. NATURE
- Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine
- (2012) Kook Hwan Kim et al. NATURE MEDICINE
- Genetic dysfunction of MT-ATP6 causes axonal Charcot-Marie-Tooth disease
- (2012) R. D. S. Pitceathly et al. NEUROLOGY
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A
- (2012) Richard D. W. Kelly et al. NUCLEIC ACIDS RESEARCH
- PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations
- (2012) Z Yao et al. ONCOGENE
- Association of Mitochondrial DNA Variations with Lung Cancer Risk in a Han Chinese Population from Southwestern China
- (2012) Shizhen Zheng et al. PLoS One
- Mitochondrial Haplogroups and Control Region Polymorphisms in Age-Related Macular Degeneration: A Case-Control Study
- (2012) Edith E. Mueller et al. PLoS One
- Humanin, a Cytoprotective Peptide, Is Expressed in Carotid Artherosclerotic Plaques in Humans
- (2012) David G. Zacharias et al. PLoS One
- Mitochondrial DNA Copy Number, but Not Haplogroup, Confers a Genetic Susceptibility to Leprosy in Han Chinese from Southwest China
- (2012) Dong Wang et al. PLoS One
- Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging
- (2012) Perry G. Ridge et al. PLoS One
- Mitochondrial Haplogroups H and J: Risk and Protective Factors for Ischemic Cardiomyopathy
- (2012) Mariana Fernández-Caggiano et al. PLoS One
- Molecular and Clinical Characterization of the Variable Phenotype in Korean Families with Hearing Loss Associated with the Mitochondrial A1555G Mutation
- (2012) Jae Woong Bae et al. PLoS One
- A Case-Control Study of Peripheral Blood Mitochondrial DNA Copy Number and Risk of Renal Cell Carcinoma
- (2012) Mark P. Purdue et al. PLoS One
- Functional Differences between Mitochondrial Haplogroup T and Haplogroup H in HEK293 Cybrid Cells
- (2012) Edith E. Mueller et al. PLoS One
- The effect of ethidium bromide and chloramphenicol on mitochondrial biogenesis in primary human fibroblasts
- (2012) Li-Pin Kao et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Reduced mitochondrial DNA copy number in Chinese patients with osteosarcoma
- (2012) Man Yu et al. Translational Research
- Global DNA methylation levels are modulated by mitochondrial DNA variants
- (2012) Dina Bellizzi et al. Epigenomics
- Rapid Mitochondrial DNA Segregation in Primate Preimplantation Embryos Precedes Somatic and Germline Bottleneck
- (2012) Hyo-Sang Lee et al. Cell Reports
- An Inherited Heteroplasmic Mutation in Mitochondrial Gene COI in a Patient with Prostate Cancer Alters Reactive Oxygen, Reactive Nitrogen and Proliferation
- (2012) Rebecca S. Arnold et al. Biomed Research International
- Mutational hotspots in the mitochondrial genome of lung cancer
- (2011) So-Jung Choi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Animal models of human mitochondrial DNA mutations
- (2011) David A. Dunn et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- A mitochondrial etiology of Alzheimer and Parkinson disease
- (2011) Pinar Coskun et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- mtDNA haplogroup J Modulates telomere length and Nitric Oxide production
- (2011) Mercedes Fernández-Moreno et al. BMC MUSCULOSKELETAL DISORDERS
- Association between mitochondrial DNA content in leukocytes and colorectal cancer risk
- (2011) Falin Qu et al. CANCER
- Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands
- (2011) Heather M. O'Hagan et al. CANCER CELL
- Mitochondrial DNA Copy Number and Pancreatic Cancer in the Alpha-Tocopherol Beta-Carotene Cancer Prevention Study
- (2011) S. M. Lynch et al. Cancer Prevention Research
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- The Human Mitochondrial Transcriptome
- (2011) Tim R. Mercer et al. CELL
- Mitochondrial Haplogroup X is associated with successful aging in the Amish
- (2011) Monique D. Courtenay et al. HUMAN GENETICS
- Complete loss of expression of theANT1gene causing cardiomyopathy and myopathy
- (2011) Andoni Echaniz-Laguna et al. JOURNAL OF MEDICAL GENETICS
- Evaluation of respiratory chain activity in lymphocytes of patients with Alzheimer disease
- (2011) Pollyana Feldhaus et al. METABOLIC BRAIN DISEASE
- PGC-1 family coactivators and cell fate: Roles in cancer, neurodegeneration, cardiovascular disease and retrograde mitochondria–nucleus signalling
- (2011) Aleck W.E. Jones et al. MITOCHONDRION
- SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities
- (2011) L. Peng et al. MOLECULAR AND CELLULAR BIOLOGY
- The ageing systemic milieu negatively regulates neurogenesis and cognitive function
- (2011) Saul A. Villeda et al. NATURE
- Telomere dysfunction induces metabolic and mitochondrial compromise
- (2011) Ergün Sahin et al. NATURE
- S14G-Humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice
- (2011) Wenjun Zhang et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Gene Expression Pattern in Transmitochondrial Cytoplasmic Hybrid Cells Harboring Type 2 Diabetes-Associated Mitochondrial DNA Haplogroups
- (2011) Seungwoo Hwang et al. PLoS One
- Modes of Metabolic Compensation during Mitochondrial Disease Using the Drosophila Model of ATP6 Dysfunction
- (2011) Alicia M. Celotto et al. PLoS One
- Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins
- (2011) O. Rackham et al. RNA
- Evolution Meets Disease: Penetrance and Functional Epistasis of Mitochondrial tRNA Mutations
- (2011) Raquel Moreno-Loshuertos et al. PLoS Genetics
- Mitochondrial–nuclear epistasis: Implications for human aging and longevity
- (2010) Gregory J. Tranah AGEING RESEARCH REVIEWS
- Cost of a Naturally Occurring Two–Amino Acid Deletion in Cytochrome c Oxidase Subunit 7A in Drosophila simulans
- (2010) J. William O. Ballard et al. AMERICAN NATURALIST
- Somatic Mitochondrial DNA Mutations in Mammalian Aging
- (2010) Nils-Göran Larsson Annual Review of Biochemistry
- Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets
- (2010) Manti Guha et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome
- (2010) Federico V. Pallardó et al. BIOGERONTOLOGY
- DNA methylation status of nuclear-encoded mitochondrial genes underlies the tissue-dependent mitochondrial functions
- (2010) Masaki Takasugi et al. BMC GENOMICS
- A novel role for mitochondria in regulating epigenetic modifications in the nucleus
- (2010) Dominic Smiraglia et al. CANCER BIOLOGY & THERAPY
- Selection of cancer cells with repressed mitochondria triggers colon cancer progression
- (2010) María Sánchez-Aragó et al. CARCINOGENESIS
- Mitochondrial DNA copy number and lung cancer risk in a prospective cohort study
- (2010) H. D. Hosgood et al. CARCINOGENESIS
- TTR familial amyloid polyneuropathy: does a mitochondrial polymorphism entirely explain the parent-of-origin difference in penetrance?
- (2010) Bernard Bonaïti et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- EARLY LIFE BENEFITS AND LATER LIFE COSTS OF A TWO AMINO ACID DELETION IN DROSOPHILA SIMULANS
- (2010) J. William O. Ballard et al. EVOLUTION
- Up-regulation of the ATPase Inhibitory Factor 1 (IF1) of the Mitochondrial H+-ATP Synthase in Human Tumors Mediates the Metabolic Shift of Cancer Cells to a Warburg Phenotype
- (2010) Laura Sánchez-Cenizo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease
- (2010) Larissa Arning et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Xenomitochondrial mice: Investigation into mitochondrial compensatory mechanisms
- (2010) M.V. Cannon et al. MITOCHONDRION
- Tissue-specific differences in mitochondrial activity and biogenesis
- (2010) Erika Fernández-Vizarra et al. MITOCHONDRION
- Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences
- (2010) Undraga Schagdarsurengin et al. Molecular Cancer
- Linking functional decline of telomeres, mitochondria and stem cells during ageing
- (2010) Ergün Sahin et al. NATURE
- Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice
- (2010) Asimina Hiona et al. PLoS One
- Evidence for Sub-Haplogroup H5 of Mitochondrial DNA as a Risk Factor for Late Onset Alzheimer's Disease
- (2010) Aurelia Santoro et al. PLoS One
- Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage
- (2009) Judith Haendeler et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Somatic mutations in mitochondrial genome and their potential roles in the progression of human gastric cancer
- (2009) Wen-Yi Hung et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer
- (2009) Peng Xia et al. BMC CANCER
- The Critical Role of the Class III Histone Deacetylase SIRT1 in Cancer
- (2009) T. Liu et al. CANCER RESEARCH
- Mitochondrial dysfunction-induced amphiregulin upregulation mediates chemo-resistance and cell migration in HepG2 cells
- (2009) C.-J. Chang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Modulation of mitochondrial protein phosphorylation by soluble adenylyl cyclase ameliorates cytochrome oxidase defects
- (2009) Rebeca Acin-Perez et al. EMBO Molecular Medicine
- A common mutation of the MYH gene is associated with increased DNA oxidation and age-related diseases
- (2009) Caixia Sun et al. FREE RADICAL BIOLOGY AND MEDICINE
- Evidence for potential functionality of nuclearly-encoded humanin isoforms
- (2009) Marek Bodzioch et al. GENOMICS
- Mitochondrial DNA background modifies the bioenergetics of NARP/MILS ATP6 mutant cells
- (2009) M. D'Aurelio et al. HUMAN MOLECULAR GENETICS
- Mitochondrial DNA depletion and fatal infantile hepatic failure due to mutations in the mitochondrial polymerase γ (POLG) gene: a combined morphological/enzyme histochemical and immunocytochemical/biochemical and molecular genetic study
- (2009) J. Müller-Höcker et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Number matters: control of mammalian mitochondrial DNA copy number
- (2009) Laura L. Clay Montier et al. Journal of Genetics and Genomics
- Mitochondrial copy number and risk of breast cancer: A pilot study
- (2009) Jie Shen et al. MITOCHONDRION
- Identification of ataxia-associated mtDNA mutations (m.4052T>C and m.9035T>C) and evaluation of their pathogenicity in transmitochondrial cybrids
- (2009) Marianna Sikorska et al. MUSCLE & NERVE
- Mitochondrial gene replacement in primate offspring and embryonic stem cells
- (2009) Masahito Tachibana et al. NATURE
- Humanin: A Novel Central Regulator of Peripheral Insulin Action
- (2009) Radhika H. Muzumdar et al. PLoS One
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA hypomethylation in cancer cells
- (2009) Melanie Ehrlich Epigenomics
- Pathogenic Mitochondrial DNA Mutations Are Common in the General Population
- (2008) Hannah R. Elliott et al. AMERICAN JOURNAL OF HUMAN GENETICS
- How mitochondria produce reactive oxygen species
- (2008) Michael P. Murphy BIOCHEMICAL JOURNAL
- A prospective study of mitochondrial DNA copy number and risk of non-Hodgkin lymphoma
- (2008) Q. Lan et al. BLOOD
- Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype
- (2008) B. Kumar et al. CANCER RESEARCH
- A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
- (2008) David J. Pagliarini et al. CELL
- Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?
- (2008) Leonard Guarente CELL
- Mitochondrial biogenesis and healthy aging
- (2008) Guillermo López-Lluch et al. EXPERIMENTAL GERONTOLOGY
- Mitochondria as Chi: Figure 1.—
- (2008) Douglas C. Wallace GENETICS
- Mitochondrial DNA background modulates the assembly kinetics of OXPHOS complexes in a cellular model of mitochondrial disease
- (2008) Rosa Pello et al. HUMAN MOLECULAR GENETICS
- Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress
- (2008) S. Ahmed et al. JOURNAL OF CELL SCIENCE
- Mitochondrial DNA Content: Its Genetic Heritability and Association With Renal Cell Carcinoma
- (2008) J. Xing et al. JNCI-Journal of the National Cancer Institute
- Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications
- (2008) Xiang-Jiao Yang et al. MOLECULAR CELL
- DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
- (2008) Marc Vermulst et al. NATURE GENETICS
- Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment
- (2008) Rebecca S. Arnold et al. PROSTATE
- Mitochondrial DNA Mutations May Contribute to Aging Via Cell Death Caused by Peptides that Induce Cytochrome c Release
- (2008) Steven J. Dubec et al. REJUVENATION RESEARCH
- ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
- (2008) K. Ishikawa et al. SCIENCE
- Inherited Mitochondrial Diseases of DNA Replication
- (2007) William C. Copeland Annual Review of Medicine
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