Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats

Comparison of Constitutional and Replication Stress-Induced Genome Structural Variation by SNP Array and Mate-Pair Sequencing

(2011) M. F. Arlt et al.   GENETICS

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers

(2011) Anne Blumrich et al.   HUMAN MOLECULAR GENETICS

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

(2011) Efrat Ozeri-Galai et al.   MOLECULAR CELL

lincRNAs act in the circuitry controlling pluripotency and differentiation

(2011) Mitchell Guttman et al.   NATURE

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

Mechanisms of Genomic Instabilities Underlying Two Common Fragile-Site-Associated Loci, PARK2 and DMD, in Germ Cell and Cancer Cell Lines

(2010) Jun Mitsui et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Breakages at common fragile sites set boundaries of amplified regions in two leukemia cell lines K562 – Molecular characterization of FRA2H and localization of a new CFS FRA2S

(2010) Franca Pelliccia et al.   CANCER LETTERS

DNA Instability at Chromosomal Fragile Sites in Cancer

(2010) Laura W. Dillon et al.   CURRENT GENOMICS

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

(2010) Martin F. Arlt et al.   DNA REPAIR

Deletion at Fragile Sites Is a Common and Early Event in Barrett's Esophagus

(2010) L. A. Lai et al.   MOLECULAR CANCER RESEARCH

Signatures of mutation and selection in the cancer genome

(2010) Graham R. Bignell et al.   NATURE

Systematic identification of fragile sites via genome-wide location analysis of γ-H2AX

(2010) Rachel K Szilard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Secondary structure formation and DNA instability at fragile site FRA16B

(2010) Allison A. Burrow et al.   NUCLEIC ACIDS RESEARCH

DNA breaks at fragile sites generate oncogenic RET/PTC rearrangements in human thyroid cells

(2010) M Gandhi et al.   ONCOGENE

Functional and Clinical Significance of Variants Localized to 8q24 in Colon Cancer

(2009) M. S. Cicek et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Common fragile sites are characterized by histone hypoacetylation

(2009) Yanwen Jiang et al.   HUMAN MOLECULAR GENETICS

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics

Stably transfected common fragile site sequences exhibit instability at ectopic sites

(2008) Ryan L. Ragland et al.   GENES CHROMOSOMES & CANCER

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings

(2008) Mitch McVey et al.   TRENDS IN GENETICS