Article
Clinical Neurology
Norma Verdolini, Marta Moreno-Ortega, Pilar Salgado-Pineda, Gemma Monte, Ana Martinez de Aragon, Monica Dompablo, Peter J. McKenna, Raymond Salvador, Tomas Palomo, Edith Pomarol-Clotet, Roberto Rodriguez-Jimenez
Summary: This study examined the brain activity of bipolar disorder patients during the Stroop task and found that there were no differences in activation between the patients and healthy subjects. However, the patients showed significant failure of de-activation in specific brain regions. These findings suggest that the regulatory component of cognitive control remains intact in bipolar disorder, but there may be dysfunction in the default mode network.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Thomas D. Meram, Asadur Chowdury, Philip Easter, Tyler Attisha, Ellanya Kallabat, Gregory L. Hanna, Paul Arnold, David R. Rosenberg, Vaibhav A. Diwadkar
Summary: This study focused on the pathology of Obsessive-Compulsive Disorder and its association with brain network profiles of the dorsal Anterior Cingulate Cortex (dACC). The research found that motor control tasks triggered greater dACC modulation in OCD patients, with different relationships between obsessions and compulsions in terms of dACC modulation during different tasks. These results highlight the importance of dACC in OCD and the role of motor control tasks in evoking dACC pathology in the disorder.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Neurosciences
Yunjin Bak, Yoonjin Nah, Sanghoon Han, Seung-Koo Lee, Jiwoong Kim, Na-Young Shin
Summary: The study found that postpartum women display higher empathy towards babies and this is associated with specific brain regions. Over time, the empathizing process towards babies in postpartum period seems to become less cognitively demanding.
HUMAN BRAIN MAPPING
(2021)
Article
Neurosciences
Maite Crespo-Garcia, Yulin Wang, Mojun Jiang, Michael C. Anderson, Xu Lei
Summary: This study investigates how people limit awareness of unwanted memories and finds that dACC plays an important role in detecting the need for memory control, while rDLPFC counters intruding thoughts that penetrate awareness.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Benjamin P. Meek, Aryandokht Fotros, Mohamed Abo Aoun, Mandana Modirrousta
Summary: Low-frequency rTMS targeting the dACC has been shown to improve error-monitoring performance and OCD symptoms in patients, with significant symptom improvement observed at one-month follow-up for those who received active stimulation. The findings suggest a link between error monitoring impairment and OCD pathophysiology.
BRAIN AND COGNITION
(2021)
Article
Clinical Neurology
Rebecca Gruzman, Corinna Hartling, Ann-Kathrin Domke, Anna Stippl, Luisa Carstens, Malek Bajbouj, Matti Gaertner, Simone Grimm
Summary: Electroconvulsive therapy (ECT) is effective for treating depression, but the neural mechanisms underlying its efficacy and markers of treatment response are not well understood. Identifying neural markers that can predict individual response to ECT would improve treatment strategies and clinical efficacy.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Endocrinology & Metabolism
Esmeralda Hidalgo-Lopez, Isabel Noachtar, Belinda Pletzer
Summary: This study investigated the influence of anti-androgenic and progestin on the resting state functional connectivity (rs-FC) between the anterior cingulate cortex (ACC) and amygdala, while controlling for the androgenicity of progestin. The results showed that regardless of the androgenicity of progestin, rs-FC between the amygdala and frontal areas, as well as between ACC and temporoparietal areas, decreased with longer duration of HC use. However, the type of progestin had different effects on the gray matter volume of the left ACC and the connectivity between bilateral ACC and the right inferior frontal gyrus.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Psychology, Clinical
Xiaolong Peng, Xiaoping Wu, Ruxue Gong, Rui Yang, Xiang Wang, Wenzhen Zhu, Pan Lin
Summary: The study identified significant changes in functional connectivity (FC) of different anterior cingulate cortex (ACC) sub-regions in major depressive disorder (MDD) patients, associated with distinct symptoms of depression. The findings provide new insights into the role of ACC sub-regions and the default network (DN) in the pathophysiology of MDD.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Brian D. Kangas, Ann M. Iturra-Mena, Mykel A. Robble, Oanh T. Luc, David Potter, Stefanie Nickels, Jack Bergman, William A. Carlezon, Diego A. Pizzagalli
Summary: This study integrated electrophysiological recordings with rodent touchscreen-based cognitive testing, creating a rat flanker task that aligns with human cognitive control research. Purple and green photographic stimuli were found to efficiently train rats and elicit expected flanker interference effects.
SCIENTIFIC REPORTS
(2021)
Article
Geriatrics & Gerontology
Juan L. Terrasa, Pedro Montoya, Carolina Sitges, Marian van Der Meulen, Fernand Anton, Ana M. Gonzalez-Roldan
Summary: The study reveals that age-related changes in resting-state brain activity are associated with increased pain perception in older adults, with older participants showing increased beta2 and beta3 activity in certain brain regions. Furthermore, hyperactivity in the anterior cingulate cortex (ACC) may underlie the altered pain perception observed in older adults.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Psychology, Biological
Stefania Conte, John E. Richards, Nathan A. Fox, Emilio A. Valadez, Marco McSweeney, Enda Tan, Daniel S. Pine, Anderson M. Winkler, Lucrezia Liuzzi, Elise M. Cardinale, Lauren K. White, George A. Buzzell
Summary: This study investigated age differences in neural responses linked to performance monitoring using a multimodal approach. The results showed that the location of the neural generators of the performance monitoring components differed across age groups, with the 12-year-old group showing activation in the dorsal anterior cingulate cortex (dACC) and the 15-year-old and adult groups showing activation posteriorly. These findings suggest that developmental changes in performance monitoring are related to changes in the underlying neural mechanisms.
Article
Multidisciplinary Sciences
Jarrod Eisma, Eric Rawls, Stephanie Long, Russell Mach, Connie Lamm
Summary: The study found that frontal midline theta-band activity is a common mechanism for initiating and executing cognitive control, but also differentiates between cognitive control mechanisms. Higher frontal midline theta power was found for trials that required more cognitive control, with reactive control and inhibitory control having higher theta power than proactive control and response conflict, and proactive control having higher theta power than response conflict. Decoding analyses successfully showed that theta representations of cognitive control generalize across multiple cognitive control strategies.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Eliza Bliss-Moreau, Anthony C. Santistevan, Jeffrey Bennett, Gilda Moadab, David G. Amaral
Summary: The study investigates the causal role of ACC in affective responding to threat in primates. Results suggest that the primate ACC is necessary for maintaining appropriate affective responses towards potentially harmful and/or novel stimuli, and that ACC lesions can lead to a reduced reactivity towards these stimuli, with implications for mood disorders.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Neurosciences
Carlos Silva, Blake S. Porter, Kristin L. Hillman
Summary: Animals must continually assess effort and physiological states during tasks, with the ACC and anterior insular cortex implicated in cost-benefit decision-making. Contrary to predictions, stimulation of Cg1 did not increase persistence in the task, while stimulation of the anterior insula had little effect on effortful behavior.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Anatomy & Morphology
Jose Francis-Oliveira, Owen Leitzel, Minae Niwa
Summary: This article discusses the nomenclature of the medial prefrontal cortex (mPFC) subdivisions, proposing a change in the naming of the rodent cingulate cortex to anterior cingulate cortex (aCg) and mid-cingulate cortex (mCg). Based on data, the authors show evidence of distinct cortico-cortical projections from aCg and mCg to the PrL, as well as a sex difference in the aCg with males having a higher proportion of layer V neurons projecting to the PrL.
FRONTIERS IN NEUROANATOMY
(2022)
Article
Clinical Neurology
Julia O. Linke, Georgia Koppe, Vanessa Scholz, Philipp Kanske, Daniel Durstewitz, Michele Wessa
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Editorial Material
Behavioral Sciences
Philipp Kanske, Ryan J. Murray
Article
Neurosciences
Malin K. Hildebrandt, Emanuel Jauk, Konrad Lehmann, Lara Maliske, Philipp Kanske
Summary: This study reveals the ecological validity of lab-based social affect and cognition paradigms in everyday social interactions. Daily social affect is predicted by social affect experienced during the EmpaToM task, while daily social cognition is associated with neural activation differences in the medial prefrontal cortex.
Review
Psychology
Matthias Schurz, Joaquim Radua, Matthias G. Tholen, Lara Maliske, Daniel S. Margulies, Rogier B. Mars, Jerome Sallet, Philipp Kanske
Summary: This study integrates evidence of brain activation, brain organization, and behavior into a coherent model of social-cognitive processes, finding a multilevel model for understanding others' mental states from neuroimaging data. The model involves cognitive, affective, and combined functions, ultimately explained by an underlying principal gradient.
PSYCHOLOGICAL BULLETIN
(2021)
Review
Psychiatry
Marcel Kurtz, Pia Mohring, Katharina Foerster, Michael Bauer, Philipp Kanske
Summary: The reviewed studies indicate impairments in explicit emotion regulation in individuals at risk for bipolar disorder, patients with manic and depressive episodes, and euthymic patients. Behavioral and neural findings regarding explicit emotion regulation in individuals at risk for bipolar disorders and euthymic patients show discrepancies, with neural differences mainly found in frontostriatal networks.
INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS
(2021)
Article
Neurosciences
Pauline Favre, Philipp Kanske, Haakon Engen, Tania Singer
Summary: Meditation-based mental training interventions have shown benefits for physical and mental health, but different types of mental practices have varying effects on emotion processing. In the ReSource project, socio-affective skills training was found to be specifically effective in improving emotion regulation capabilities when facing adversity.
Article
Multidisciplinary Sciences
Julia Stietz, Lena Pollerhoff, Marcel Kurtz, Shu-Chen Li, Andrea M. F. Reiter, Philipp Kanske
Summary: As population ageing is expected to reach unprecedented levels in this century, research in various fields has shifted focus towards factors contributing to healthy ageing, particularly in promoting well-being until old age. The impact of human interactions on mental and physical health has led scientists to investigate the basic processes enabling successful social interactions, such as social affect and cognition. Reproducibility of findings in psychological science, amidst a replication crisis, remains crucial in understanding how social affect and cognition change across the adult lifespan. Our study aimed to replicate the effects of age on empathy, compassion, and Theory of Mind, confirming previous results of preservation or enhancement in socio-affective processes, alongside a decline in socio-cognitive processes for older adults, offering insights for intervention studies to foster successful social interactions and well-being into advanced old age.
ROYAL SOCIETY OPEN SCIENCE
(2021)
Article
Psychology, Social
Emanuel Jauk, Lisa Ulbrich, Paul Jorschick, Michael Hoefler, Scott Barry Kaufman, Philipp Kanske
Summary: Objective narcissism can manifest in grandiose and vulnerable patterns of experience and behavior. In individuals with clinically relevant narcissism, grandiosity and vulnerability traits are related at high levels. These findings help to link personality and clinical models.
JOURNAL OF PERSONALITY
(2022)
Article
Psychology, Experimental
Brennan McDonald, Anne Boeckler, Philipp Kanske
Summary: Music has the ability to influence our understanding and empathy towards others. Emotional music can enhance social affect and empathy, but does not have an impact on social cognition. These findings contribute to evidence for separable processes within the social mind.
Article
Neurosciences
Stefan Schulreich, Anita Tusche, Philipp Kanske, Lars Schwabe
Summary: This study investigates the impact of stress on altruistic decision-making and the underlying neurocognitive mechanisms. The findings suggest that the stress hormone cortisol modulates mentalizing-related processes, leading to a decrease in altruism.
JOURNAL OF NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Konrad Lehmann, Anne Boeckler, Olga Klimecki, Christian Mueller-Liebmann, Philipp Kanske
Summary: Cooperation is crucial in a world with increasing population and limited resources. Empathy and mentalizing both play a positive role in enhancing prosocial behavior.
SCIENTIFIC REPORTS
(2022)
Review
Clinical Neurology
Katharina Foerster, Lara. Z. Maliske, Matthias Schurz, Paula. M. Henneberg, Udo Dannlowski, Philipp Kanske
Summary: A systematic literature review and meta-analysis revealed that patients with manic bipolar disorder demonstrate increased emotional reactivity and decreased emotion regulation compared to healthy participants, particularly in the processing of negative stimuli. The findings emphasize the importance of longitudinal studies to further understand changes in emotion processing.
Article
Psychology, Experimental
Jost Ulrich Blasberg, Joana Jost, Philipp Kanske, Veronika Engert
Summary: The closeness of the parent-child relationship determines the likelihood of children spontaneously reproducing the emotional and physiological stress response of their mothers. This study investigated whether psychosocial stress in mothers is causally linked to empathic stress in children. The findings showed that children in the stress group were more likely to exhibit significant cortisol release, particularly boys. Watching stressed mothers also triggered stronger subjective and physiological stress responses in children, with the latter being influenced by cognitive empathy. Only in stressed parent-child pairs did the children's physiological responses resonate with those of their mothers. In conclusion, young children are capable of spontaneously reproducing their mother's stress response, even when mildly stressed.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2023)
Article
Psychology, Multidisciplinary
Tatjana Koepernik, Emanuel Jauk, Philipp Kanske
Summary: In public discourse, narcissism is often portrayed negatively but psychological theories suggest a more complex phenomenon. Research shows that people tend to attribute grandiose narcissism to feelings of superiority and vulnerable narcissism to feelings of inferiority. Endorsement of different implicit theories is related to prior knowledge of narcissism, while likability of narcissism is associated with perceivers' own narcissism levels. This suggests that people tend to employ a "it is what it seems" heuristic when facing narcissistic behaviors, and are less likely to attribute such behaviors to incongruent motivational states.
CURRENT PSYCHOLOGY
(2022)
Article
Psychology, Experimental
Fynn-Mathis Trautwein, Philipp Kanske, Anne Boeckler, Tania Singer
