期刊
HUMAN & EXPERIMENTAL TOXICOLOGY
卷 30, 期 2, 页码 165-170出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0960327110368694
关键词
blood cancer; chromosomal aberrations; arsenic
类别
资金
- Council of Scientific and Industrial Research, New Delhi, India [110012]
- [09/945/( 0001)/2005-EMR-I]
Arsenic is a naturally occurring metalloid that has been associated with increased incidence of human cancers in certain highly exposed populations. This present work aimed to study whether arsenic plays any role in the increased incidence of blood cancer among residents of West Bengal, India, which is one of the worst arsenic-affected areas of the world. Our study group included both blood cancer patients and age-, sex-matched healthy controls. We studied the arsenic concentration in the hair and nail samples of our study group. We found significantly higher arsenic concentration in the biological tissues of patients, which also correlated with their greater incidence of chromosomal aberrations. Thus, arsenic may act as a predisposing factor for blood cancer.
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