Blockade of 2-arachidonoylglycerol hydrolysis produces antidepressant-like effects and enhances adult hippocampal neurogenesis and synaptic plasticity

Endocannabinoid Signaling in the Etiology and Treatment of Major Depressive Illness

(2014) Cecilia Hillard et al.   CURRENT PHARMACEUTICAL DESIGN

Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice

(2014) Balapal S. Basavarajappa et al.   HIPPOCAMPUS

Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling

(2014) Peng Zhong et al.   NEUROPSYCHOPHARMACOLOGY

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

(2013) Alline C. Campos et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

mTOR Inhibition Ameliorates Cognitive and Affective Deficits Caused by Disc1 Knockdown in Adult-Born Dentate Granule Neurons

(2013) Miou Zhou et al.   NEURON

Functional circuits of new neurons in the dentate gyrus

(2013) Carmen Vivar et al.   Frontiers in Neural Circuits

A Dysregulated Endocannabinoid-Eicosanoid Network Supports Pathogenesis in a Mouse Model of Alzheimer's Disease

(2012) Justin R. Piro et al.   Cell Reports

Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

(2012) Rongqing Chen et al.   Cell Reports

Differential Role of Anandamide and 2-Arachidonoylglycerol in Memory and Anxiety-like Responses

(2011) Arnau Busquets-Garcia et al.   BIOLOGICAL PSYCHIATRY

Alterations of Endocannabinoid Signaling, Synaptic Plasticity, Learning, and Memory in Monoacylglycerol Lipase Knock-out Mice

(2011) B. Pan et al.   JOURNAL OF NEUROSCIENCE

Depression, Antidepressants and Neurogenesis: A Critical Reappraisal

(2011) Nicola D Hanson et al.   NEUROPSYCHOPHARMACOLOGY

Reversible Gating of Endocannabinoid Plasticity in the Amygdala by Chronic Stress: A Potential Role for Monoacylglycerol Lipase Inhibition in the Prevention of Stress-Induced Behavioral Adaptation

(2011) Joshua J Sumislawski et al.   NEUROPSYCHOPHARMACOLOGY

Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats

(2011) Natale R. Sciolino et al.   PHARMACOLOGICAL RESEARCH

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

(2010) Susanne A Wolf et al.   Cell Communication and Signaling

Loss of Retrograde Endocannabinoid Signaling and Reduced Adult Neurogenesis in Diacylglycerol Lipase Knock-out Mice

(2010) Y. Gao et al.   JOURNAL OF NEUROSCIENCE

Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

(2010) Steven G. Kinsey et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

(2010) N. Li et al.   SCIENCE

The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair

(2009) Nina S. Corsini et al.   Cell Stem Cell

Characterization of Monoacylglycerol Lipase Inhibition Reveals Differences in Central and Peripheral Endocannabinoid Metabolism

(2009) Jonathan Z. Long et al.   CHEMISTRY & BIOLOGY

Reduced expression of glutamate receptors and phosphorylation of CREB are responsible forin vivoΔ9-THC exposure-impaired hippocampal synaptic plasticity

(2009) Ni Fan et al.   JOURNAL OF NEUROCHEMISTRY

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

DISC1 Regulates New Neuron Development in the Adult Brain via Modulation of AKT-mTOR Signaling through KIAA1212

(2009) Ju Young Kim et al.   NEURON

The Therapeutic Potential of the Endocannabinoid System for the Development of a Novel Class of Antidepressants

(2009) Matthew N. Hill et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The cannabinoid CB1receptor and the endocannabinoid anandamide: possible antidepressant targets

(2008) Francis Rodriguez Bambico et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

(2008) J.-W. Wang et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid Signaling Mediates Cocaine-Induced Inhibitory Synaptic Plasticity in Midbrain Dopamine Neurons

(2008) B. Pan et al.   JOURNAL OF NEUROSCIENCE

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology