4.2 Article

CYCLOADDITION REACTIONS OF AZIDE, FURAN, AND PYRROLE UNITS WITH BENZYNES GENERATED BY THE HEXADEHYDRO-DIELS ALDER (HDDA) REACTION

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HETEROCYCLES
卷 88, 期 2, 页码 1191-1200

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-13-S(S)83

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  1. National Cancer Institute [CA76497]
  2. National Institute of General Medical Sciences of the United States Department of Health and Human Services (DHHS) [GM65597]

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Benzynes can be generated by the intramolecular thermal cycloisomerization of triynes the title HDDA reaction. We report here that these can be trapped by cycloaddition reaction with trimethylsilyl azide (1,3-dipolar) or a furan or pyrrole (4+2 Diels-Alder).

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