Editorial Material
Chemistry, Multidisciplinary
Qian Miao
Summary: Recent findings on the skeletal rearrangement of polycyclic aromatics under oxidative and acidic conditions are expected to advance the development of Scholl reactions into a more rational design-based method for synthesizing polycyclic aromatics with greater utility and versatility.
NATURE REVIEWS CHEMISTRY
(2021)
Article
Chemistry, Organic
Cristian Cavedon, Eric T. Sletten, Amiera Madani, Olaf Niemeyer, Peter H. Seeberger, Bartholomaeus Pieber
Summary: A visible-light-mediated debenzylation method has been proposed to make benzyl ethers temporary protective groups, enabling new orthogonal protection strategies and compatibility with multiple functional groups simultaneously.
Article
Multidisciplinary Sciences
M. Rbaa, A. Hichar, P. Dohare, El H. Anouar, Y. Lakhrissi, B. Lakhrissi, M. Berredjem, F. Almalki, V. Rastija, M. Rajabi, T. Ben Hadda, A. Zarrouk
Summary: The study introduces the synthesis of a new family of organic compounds based on 8-hydroxyquinoline using a simple and efficient method. The compounds show potent antibacterial activity against both Gram-positive and Gram-negative strains, with effectiveness at low concentrations. The antibacterial activity has also been optimized through bioinformatics studies.
ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
(2021)
Article
Chemistry, Organic
Heesun Yu, Ryangha Lee, Hyoungsu Kim, Dongjoo Lee
Summary: This study presents a diastereoselective synthesis method for trans-2-alkyl-6-aryl-3,6-dihydro-2H-pyrans, with good yield and moderate to excellent diastereoselectivity. The utility of this method was demonstrated in the total synthesis of two natural products.
Article
Chemistry, Organic
Abhishek Kar, Baitan Chakraborty, Sandip Kundal, Gopal Rana, Umasish Jana
Summary: A series of diverse and complex hybrid structures containing fluorene were successfully obtained with high regioselectivity from biaryl tethered 3-(methylene)indoline under mild conditions. The addition of additives such as FeCl3 and molecular sieves significantly improved the yield of the products. The strategy involves tandem allylic Csp(3)-H oxidation and subsequent intramolecular carbon-carbon bond formation.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Psychiatry
Jing Song Wang, Jing Lin Liu, Jun Zhang, Jun Tan, Ting Huang, Chun Xia Lu, Xi Yang Peng, Yin Guo, Lan Zheng
Summary: The study investigated the association between peripheral blood oxytocin and social anxiety disorder in female heroin addicts, as well as the impact of exercise on SAD and oxytocin levels. The results showed that exercise significantly increased oxytocin levels and reduced the severity of social anxiety disorder and cravings in female heroin addicts.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Chemistry, Organic
Tanumoy Mandal, Aznur Azim, Sanju Das, Suman De Sarkar
Summary: An efficient method for the E-selective synthesis of nitroolefins has been developed using DDQ as the organophotoredox catalyst, with tert-BuONO (TBN) as the nitrating agent under visible-light irradiation. The green transition metal-free approach utilizes aerial oxygen as the terminal oxidant and occurs at room temperature. A total of 41 different olefins with a broad diversity of substituents were nitrated successfully using this established protocol.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Mingliang Wang, Dongping Cheng, Yueqi Pu, Xiaoliang Xu
Summary: A DDQ-mediated tandem annulation of 2-aminochromones with 1,3-diarylpropenes is described for the synthesis of azaxanthones in moderate to good yields. The reaction involves oxidative coupling, intramolecular cyclization, and dehydro-aromatization, showcasing high atom efficiency.
TETRAHEDRON LETTERS
(2021)
Article
Chemistry, Organic
Samuzal Bhuyan, Abhijit Gogoi, Joneswar Basumatary, Biswajit Gopal Roy
Summary: An atom-economic visible-light photocatalytic approach has been developed for the synthesis of diverse aryl alcohols, ethers, and esters through direct C-H functionalization. This method uses DDQ as a photocatalyst and TBN as a co-catalyst, allowing for the substitution of aromatic C-H by neutral nucleophile oxygen and utilizing aerobic oxygen as the terminal oxidant to produce water as the sole by-product.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Asim Kumar Ghosh, Sukanya Neogi, Krishna Kanta Das, Alakananda Hajra
Summary: An efficient, metal-free, and direct oxidative amination of aldehyde-derived hydrazones with azoles has been developed using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone as an organocatalyst at ambient temperature. This protocol provides a wide range of aminated hydrazone derivatives in a step and atom economical fashion. The reaction possibly follows a radical mechanism.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Plant Sciences
Chao Xue, Guanqing Liu, Shang Sun, Xiaoyu Liu, Rui Guo, Zhukuan Cheng, Hengxiu Yu, Minghong Gu, Kai Liu, Yong Zhou, Tao Zhang, Zhiyun Gong
Summary: This research discovered the formation of neocentromeres in rice, which are assembled at DNA loci not previously associated with CenH3 nucleosomes. Neocentromeres can rescue rearranged chromosomes that have lost a functional centromere and avoid chromosomal regions containing functional genes. It was also found that canonical histone H3 was replaced by CENH3 in regions with low CENH3 levels.
Article
Spectroscopy
C. Balraj, S. Balaji, M. Karthikeyan
Summary: A study on the molecular charge-transfer interaction between a series of electron pi-acceptors and selected donors reveals consistent results between experimental and theoretical analyses. The order of complex formation strengths between donors and acceptors is observed, along with the identification of interaction sites on the donor molecules complexed with acceptors.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Organic
Tianci Li, Jiangyu Yang, Xin Yin, Jinhua Shi, Qun Cao, Miaomiao Hu, Xiaowen Xu, Meichao Li, Zhenlu Shen
Summary: A metal-free photocatalytic Ritter-type C-H amination utilizing molecular oxygen as a terminal oxidant has been developed, offering a cost-effective and sustainable method for synthesizing a broad range of secondary amides under mild conditions.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Microbiology
Xinhong Peng, Beilei Wu, Shuaihu Zhang, Mei Li, Xiliang Jiang
Summary: Trichoderma species are widely used biocontrol agents with antagonistic properties against various plant pathogens. Chlamydospores, produced by many fungi, have thick walls and high resistance to adverse conditions. Chlamydospores of Trichoderma spp. have better application potential and longer shelf life, but large-scale production remains difficult. By conducting a comprehensive analysis of transcriptome dynamics during chlamydospore formation, important pathways and genes involved in each stage were identified.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Engineering, Chemical
A. F. M. Motiur Rahman, Ahmed H. Bakheit, Shofiur Rahman, Gamal A. E. Mostafa, Haitham Alrabiah
Summary: In this study, two new charge transfer (CT) complexes, procainamide-chloranilic acid (PA-ChA) and procainamide-2,3-dichloro-5,6-dicyano-1,4-benzoquinone (PA-DDQ), were synthesized and characterized using various spectroscopic methods. The stability of each complex was investigated using spectroscopic parameters, and the formation of CT complexes in solution was confirmed by spectrophotometric determination. Density functional theory (DFT) calculations supported the experimental results, showing consistent interaction energies and Gibbs free energies.
