Article
Chemistry, Organic
Man Ki Sit, Hui Hui Cao, Yan-Dong Wu, Tsz Chun Yip, Lars Eric Bendel, Wen Zhang, Wei-Min Dai
Summary: The synthesis of C19-truncated maltepolide E was achieved using a diene-ene ring-closing metathesis strategy, while preserving the integrity of the C11-C14 alkenyl epoxy unit. Removal of the C17-OH group resulted in its attack at the C14 position, causing double bond migration and epoxide ring opening to produce C19-truncated maltepolides A and B, which are proposed intermediates in the biosynthesis of maltepolides.
Review
Biochemistry & Molecular Biology
Martin Kalnik, Peter Gabko, Maros Bella, Miroslav Koos
Summary: Hydantoins and their hybrids with other molecules play important roles in medicinal and agrochemical applications due to their diverse biological and pharmacological activities. The Bucherer-Bergs reaction provides an efficient and simple method for the synthesis of hydantoins, which can be used in the preparation of important natural products and new organic compounds.
Article
Chemistry, Multidisciplinary
You-Cai Xiao, Xiao-Pan Chen, Ji Deng, Yu-Hang Yan, Kai-Rong Zhu, Gen Li, Jun-Lin Yu, Jurgen Brem, Fener Chen, Christopher J. Schofield, Guo-Bo Li
Summary: Chiral 3-substituted benzoxaboroles were synthesized as carbapenemase inhibitors and some were found to efficiently restore the activity of meropenem in bacteria harboring carbapenemases. The combination of structure-based design approach with asymmetric catalysis leads to potent beta-lactamase inhibitors, offering a potential starting point for developing drugs combating carbapenemases.
CHEMICAL COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Zhenxing Liu, Fangjie Deng, Yuan Zhou, Yanjie Liang, Cong Peng, Bing Peng, Feiping Zhao, Zhihui Yang, Liyuan Chai
Summary: The effect of iodine-containing transport agents I-2 and boron triiodide (BI3) on the synthesis and growth of BAs was investigated. It was found that BI3 accelerates the synthesis and improves the quality of BAs crystals. The coordinated effect of BI3 enhances the anisotropy and element uniformity of BAs crystals and facilitates the preparation of high-quality BAs crystal seeds.
INTERNATIONAL JOURNAL OF MINERALS METALLURGY AND MATERIALS
(2022)
Article
Chemistry, Organic
Hayato Tsurugi, Minami Matsuno, Tomomi Kawakami, Kazushi Mashima
Summary: N,N'-Bis(trimethylsilyl)-1,4-dihydropyrazines can be used to synthesize alkylpyrazines by combining with aldehydes and tetra(n-butyl)ammonium fluoride. Various sources of alkyl substituents, such as aryl, heteroaryl, and alkyl aldehydes, can be utilized with good yields obtained from reactions with electron-rich aldehydes. DFT calculations clarified the overall reaction sequence, with the key steps being the activation of the N-trimethylsilyl moiety by fluoride and the subsequent C-C bond formation with aldehydes.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Luka Baresic, Davor Margetic, Zoran Glasovac
Summary: The reaction of furfuryl guanidines with dienophiles showed a strong reaction dependence on the nucleophilicity of the counterion and the structure of guanidine, allowing for control over the selectivity of the reaction products.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Organic
Sushree Ranjan Sahoo, Vinod K. Singh
Summary: Here, we report an enantioselective Bronsted acid catalyzed addition of naphthols to in situ generated naphthol-derived ortho-quinone methides (o-QMs) followed by intramolecular cyclization, which provides a one-pot synthesis of substituted chiral xanthene derivatives under mild conditions. The use of chiral phosphoric acid (CPA) catalyst allows for the conversion of naphthol-derived ortho-hydroxyl benzylic alcohols into reactive naphthol-derived o-QMs, enabling control over the enantioselectivity of the carbon-carbon bond-forming event via hydrogen-bonding and intramolecular cyclization. Additionally, we demonstrate a Bronsted acid catalyzed C(sp2)-C(sp3) bond cleavage of naphthol-derived ortho-hydroxyl benzylic alcohols for the first time, providing a synthetic route to achiral xanthene derivatives in good to excellent yields.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Majharul Haque Khan, Chao Han, Xuefei Wang, Weijie Li, Guojin Zhang, Zhenguo Huang
Summary: This research presents a simple and effective method for preparing silver closo dodecaborate (Ag2B12H12) films using an electrochemical route. The size of the Ag2B12H12 particles in the films can be controlled by adjusting the electrochemical parameters. Ag nanoclusters with controllable sizes can be generated by electrochemical reduction reactions or thermal anneal. These Ag nanoparticles show promising performance for hydrogen evolution reaction (HER) in an acidic solution. This study provides new insights into the synthesis of [B12H12](2-) based thin films, the generation of metal nano-powders, and their application in HER or other applications.
Article
Chemistry, Physical
Chunhua Du, Yue Chen, Song He, Chichi Ruan, Xinyu Liu, Chunxiang He, Xin Jin, Qilin Chen, Yuansheng Ma, Guanyu Chen
Summary: This study reported a method for preparing ultra-flexible silica aerogels using the diene synthesis reaction. These aerogels exhibit high strain, super hydrophobicity, and higher adsorption capacity compared to conventional silica aerogels. They also demonstrate efficient cycle performance for adsorption and filtration.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Applied
Jana Sendra, Oriol Salvado, Manuel Pedron, Efraim Reyes, Tomas Tejero, Elena Fernandez, Pedro Merino, Jose L. Vicario
Summary: The ability of cyclooctatetraene oxide to undergo ring contraction events under mild conditions using Bronsted acid catalysis has been investigated. Selectivity was found to be controlled by catalyst acidity and temperature, leading to either cycloheptatriene carbaldehyde or phenylacetaldehyde products. A mechanistic understanding of the reaction and the influence of the catalyst has been provided through experimental and computational data. Moreover, the acid-catalyzed ring contraction has been combined with in situ enantioselective allylation reaction, resulting in enantioenriched cycloheptatrienyl-substituted homoallylic alcohols. These alcohols have further been converted to enantioenriched oxaborinanes through copper-catalyzed nucleophilic borylation/cyclization protocol.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Materials Science, Ceramics
Raman Mnatsakanyan, Artur Aghoyan, Davit Davtyan
Summary: Boron monoposphide (BP) has unique physical and chemical characteristics, making it suitable for various practical applications. However, the difficult synthesis of the single phase of boron monophosphide limits its usage. Additionally, existing methods for synthesizing nanoscale BP often require high temperatures and long synthesis durations. This paper presents a simple, energy-efficient, and straightforward microwave activation synthesis method, which successfully produces pure single-phase BP nanopowder with a narrow size distribution (70-90 nm) in a short synthesis time (10 min).
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Applied
Shujuan Wang, Lu Wang, Hongzhe Su, Chenhui Li, Wei Fan, Xinli Jing
Summary: By adding boron-containing phenolic resin (BPR) to ethylene-propylene-diene monomer (EPDM), the char yield and ablation performance of EPDM were significantly improved. The formation of boron oxide (B2O3) during pyrolysis played a crucial role in inhibiting the formation of carbon oxides and reducing carbon loss. Additionally, the addition of BPR also improved the graphitization degree of carbonization product.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Chemistry, Multidisciplinary
Hui Fu, Nan Zhang, Feili Lai, Longsheng Zhang, Zhenzhong Wu, Hanjun Li, Haiyan Zhu, Tianxi Liu
Summary: A novel B-doped Ni-based catalyst with surface strain modulation is reported for high selective and productive two-electron ORR to produce H2O2. The catalyst exhibits excellent activity, stability, and Faraday efficiency, providing a new direction for the design of highly active and stable catalysts.
Article
Chemistry, Physical
Chi Nghia Nguyen, Thuy Tien Nguyen Tran, Thuy-Kieu Truong, Thi Anh Le, Thong Nguyen-Minh Le, Linh Ho Thuy Nguyen, Chi Cuong Nguyen, Ngoc Quang Tran
Summary: Seawater electrolysis is a sustainable method for mass production of high-purity hydrogen fuel. However, the slow kinetics of the cathodic hydrogen evolution reaction (HER) limits its efficiency for large-scale applications. In this study, a general strategy to activate three-dimensional (3D) NiCoP hollow nanorod arrays through boron doping was proposed, resulting in improved water dissociation. The boron-doped NiCoP hollow nanorod arrays exhibited high cathodic current densities and long-term stability, demonstrating excellent HER activity in seawater.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Crystallography
Junkai Li, Donghan Jia, Guoliang Niu, Peiyang Mu, Huiyang Gou
Summary: Hexagonal boron nitride (h-BN) with tubular-like features can be synthesized at room temperature and high pressure by compressing ammonium azide and boron powder. The obtained h-BN has a size of 70 nanometers in length and 27 nanometers in width. This method shows promise for the preparation of other nitrides at high pressure and room temperature.
