期刊
HEPATOLOGY INTERNATIONAL
卷 12, 期 4, 页码 315-329出版社
SPRINGER
DOI: 10.1007/s12072-018-9884-8
关键词
Hepatitis B virus; Viral hepatitis; Global prevalence; Chronic liver disease; Seroprevalence
资金
- AASLD Foundation Clinical and Translational Research Award in Liver Diseases
Chronic hepatitis B virus infection (HBV) continues to pose a serious global health threat in many areas of the world, particularly in sub-Saharan Africa, the Western Pacific Region and areas of Eastern Europe. Endemicity is heterogeneous within and across regions owing to variable implementation of childhood and birth-dose vaccination programs, inconsistent screening of blood products, injection drug use, and poor education initiatives. This review aims to provide comprehensive up-to-date estimates of global seroprevalence of chronic HBV across six World Health Organization (WHO) regions, noting patterns of change over time and highlighting potential region-specific barriers to the diagnosis and elimination of HBV.
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