Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway

Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes

(2014) Masao Honda et al.   HEPATOLOGY

Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

(2013) James C. Lee et al.   CELL

Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890

(2013) Christophe Hézode et al.   JOURNAL OF HEPATOLOGY

Treatment decisions and contemporary versus pending treatments for hepatitis C

(2013) Paul M. Trembling et al.   Nature Reviews Gastroenterology & Hepatology

HCV NS3 protease enhances liver fibrosis via binding to and activating TGF-β type I receptor

(2013) Kotaro Sakata et al.   Scientific Reports

Efficacy and safety of boceprevir plus peginterferon–ribavirin in patients with HCV G1 infection and advanced fibrosis/cirrhosis

(2012) Savino Bruno et al.   JOURNAL OF HEPATOLOGY

Non-Smad signaling pathways

(2011) Yabing Mu et al.   CELL AND TISSUE RESEARCH

Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C

(2011) Masao Honda et al.   GASTROENTEROLOGY

Auto-activation of c-JUNGene by Amino Acid Deprivation of Hepatocellular Carcinoma Cells Reveals a Novel c-JUN-mediated Signaling Pathway

(2011) Lingchen Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissection of Wnt5a-Ror2 Signaling Leading to Matrix Metalloproteinase (MMP-13) Expression

(2011) Kaoru Yamagata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential interferon signaling in liver lobule and portal area cells under treatment for chronic hepatitis C

(2010) Masao Honda et al.   JOURNAL OF HEPATOLOGY

Identification of a Novel Amino Acid Response Pathway Triggering ATF2 Phosphorylation in Mammals

(2009) C. Chaveroux et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

Suppression of Programmed Cell Death 4 (PDCD4) Protein Expression by BCR-ABL-regulated Engagement of the mTOR/p70 S6 Kinase Pathway

(2008) Nathalie Carayol et al.   JOURNAL OF BIOLOGICAL CHEMISTRY