Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice

Inhibition of heat shock protein 90 (HSP90) as a therapeutic strategy for the treatment of myeloma and other cancers

(2011) Paul G. Richardson et al.   BRITISH JOURNAL OF HAEMATOLOGY

A Phase I Study of the Heat Shock Protein 90 Inhibitor Alvespimycin (17-DMAG) Given Intravenously to Patients with Advanced Solid Tumors

(2011) Simon Pacey et al.   CLINICAL CANCER RESEARCH

Lipopolysaccharide binding protein inhibitory peptide protects against acetaminophen-induced hepatotoxicity

(2010) G. L. Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis

(2010) Julio Madrigal-Matute et al.   CARDIOVASCULAR RESEARCH

Febrile range temperature represses TNF-α gene expression in LPS-stimulated macrophages by selectively blocking recruitment of Sp1 to the TNF-α promoter

(2010) Zachary A. Cooper et al.   CELL STRESS & CHAPERONES

Novel therapeutic strategies in multiple myeloma: role of the heat shock protein inhibitors

(2010) Alessandro Allegra et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents

(2010) Le-Xing Yu et al.   HEPATOLOGY

The role of intestinal endotoxin in liver injury: A long and evolving history

(2010) James P. Nolan   HEPATOLOGY

EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity

(2010) T. J. Yun et al.   JOURNAL OF IMMUNOLOGY

Dual Role of Heat Shock Proteins as Regulators of Apoptosis and Innate Immunity

(2010) Anne-Laure Joly et al.   Journal of Innate Immunity

A human MAP kinase interactome

(2010) Sourav Bandyopadhyay et al.   NATURE METHODS

Heat-shock protein expression in leukemia

(2010) Lucie Sedlackova et al.   TUMOR BIOLOGY

Alcoholic liver disease and the gut-liver axis

(2010) Gyongyi Szabo   WORLD JOURNAL OF GASTROENTEROLOGY

Febrile-range temperature modifies cytokine gene expression in LPS-stimulated macrophages by differentially modifying NF-κB recruitment to cytokine gene promoters

(2009) Zachary A. Cooper et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Modulation of Hsf1 activity by novobiocin and geldanamycin

(2009) Renaud Conde et al.   Biochemistry and Cell Biology

CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

(2009) Yongke Lu et al.   Genes and Nutrition

Targeting heat shock protein 90 with non-quinone inhibitors: A novel chemotherapeutic approach in human hepatocellular carcinoma

(2009) Marco Breinig et al.   HEPATOLOGY

Heat-shock Protein 90 Is Essential for Stabilization of the Hepatitis C Virus Nonstructural Protein NS3

(2009) Saneyuki Ujino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide triggered TNF-α-induced hepatocyte apoptosis in a murine non-alcoholic steatohepatitis model

(2009) Hiroshi Kudo et al.   JOURNAL OF HEPATOLOGY

Heat Shock Transcription Factor 1 Inhibits Expression of IL-6 through Activating Transcription Factor 3

(2009) R. Takii et al.   JOURNAL OF IMMUNOLOGY

Heat Shock Co-Activates Interleukin-8 Transcription

(2008) Ishwar S. Singh et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Small molecule inhibitors of Hsp90 potently affect inflammatory disease pathways and exhibit activity in models of rheumatoid arthritis

(2008) John W. Rice et al.   ARTHRITIS AND RHEUMATISM

Innate immunity meets with cellular stress at the IKK complex: Regulation of the IKK complex by HSP70 and HSP90

(2008) Antero Salminen et al.   IMMUNOLOGY LETTERS

Alcohol exposure regulates heat shock transcription factor binding and heat shock proteins 70 and 90 in monocytes and macrophages: implication for TNF-α regulation

(2008) Pranoti Mandrekar et al.   JOURNAL OF LEUKOCYTE BIOLOGY