Daphnane-Type Diterpenoids from the Flower Buds of Daphne genkwa

Three new daphnane-type diterpenoids, genkwanines M-O (1-3, resp.), together with seven known daphnane-type diterpenoids, genkwanines D and H, genkwaine F, genkwadaphnine, yuanhuatine, yuanhuafine, and yuanhuapine (4-10, resp.), were isolated from the flower buds of Daphne genkwa during a phytochemical investigation. The structures of the new compounds were elucidated on the basis of spectroscopic analyses, especially 2D-NMR spectra (HSQC, HMBC, and NOESY).