Bone morphogenetic protein-4: a novel therapeutic target for pathological cardiac hypertrophy/heart failure

BMP4 Increases Canonical Transient Receptor Potential Protein Expression by Activating p38 MAPK and ERK1/2 Signaling Pathways in Pulmonary Arterial Smooth Muscle Cells

(2013) Xiaoyan Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Bone morphogenetic protein-4 contributes to the down-regulation of Kv4.3 K+ channels in pathological cardiac hypertrophy

(2013) Bo Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis

(2013) Paolo Poggio et al.   CARDIOVASCULAR RESEARCH

SMAD1 Deficiency in Either Endothelial or Smooth Muscle Cells Can Predispose Mice to Pulmonary Hypertension

(2013) Chul Han et al.   HYPERTENSION

Therapeutic Impact of Follistatin-Like 1 on Myocardial Ischemic Injury in Preclinical Models

(2012) Yasuhiro Ogura et al.   CIRCULATION

LRP1-Dependent Endocytic Mechanism Governs the Signaling Output of the Bmp System in Endothelial Cells and in Angiogenesis

(2012) Xinchun Pi et al.   CIRCULATION RESEARCH

BMP signaling in vascular diseases

(2012) Jie Cai et al.   FEBS LETTERS

Bone Morphogenetic Protein-4 Mediates Cardiac Hypertrophy, Apoptosis, and Fibrosis in Experimentally Pathological Cardiac Hypertrophy

(2012) Bo Sun et al.   HYPERTENSION

Endothelial Dysfunction in Diabetes and Hypertension

(2012) Wing Tak Wong et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Abcc6 Deficiency Causes Increased Infarct Size and Apoptosis in a Mouse Cardiac Ischemia-Reperfusion Model

(2011) Imran N. Mungrue et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Heart Disease and Stroke Statistics—2012 Update

(2011) et al.   CIRCULATION

Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation

(2011) Rachana Sainger et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Bone morphogenic protein-4 induces endothelial cell apoptosis through oxidative stress-dependent p38MAPK and JNK pathway

(2011) Xiao Yu Tian et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Calcineurin and Electrical Remodeling in Pathologic Cardiac Hypertrophy

(2011) Hui-Bin Liu et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Bone Morphogenic Protein-4 Impairs Endothelial Function Through Oxidative Stress–Dependent Cyclooxygenase-2 Upregulation

(2010) Wing Tak Wong et al.   CIRCULATION RESEARCH

Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway

(2010) Alok S. Pachori et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies

(2010) Bianca C. Bernardo et al.   PHARMACOLOGY & THERAPEUTICS

In VivoStructure−Activity Relationship Study of Dorsomorphin Analogues Identifies Selective VEGF and BMP Inhibitors

(2009) Jijun Hao et al.   ACS Chemical Biology

Site-specific Cleavage of BMP4 by Furin, PC6, and PC7

(2009) Sylvia M. Nelsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells

(2008) Anna Csiszar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

BMP-2/4 and BMP-6/7 Differentially Utilize Cell Surface Receptors to Induce Osteoblastic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells

(2008) Karen Lavery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic interaction between Bmp2 and Bmp4 reveals shared functions during multiple aspects of mouse organogenesis

(2008) Devorah C. Goldman et al.   MECHANISMS OF DEVELOPMENT