Review
Biochemical Research Methods
Davood Khoeini, Timothy F. Scott, Adrian Neild
Summary: Research shows that environmental control offered by microfluidic systems can achieve non-equilibrium reaction conditions, leading to complex self-assembled structures. The study demonstrates that kinetically-controlled self-assembly can be achieved through alterations to the immediate microenvironment.
Article
Engineering, Chemical
Chuan-Fu Deng, Shi-Hao Yang, Rui Xie, Xiao-Jie Ju, Zhuang Liu, Da-Wei Pan, Jianhong Xu, Guangsheng Luo, Wei Wang, Liang-Yin Chu
Summary: A strategy based on stepwise nesting of basic fractal networks is proposed for modular microfluidic integration, which enables more flexible choices of microchannel dimensions for uniform flow distribution. Compared to the control group, the nested fractal networks can significantly improve the monodispersity of droplet size.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Biochemical Research Methods
Deepshika Gilbile, Megan L. Shelby, Artem Y. Lyubimov, Jennifer L. Wierman, Diana C. F. Monteiro, Aina E. Cohen, Silvia Russi, Matthew A. Coleman, Matthias Frank, Tonya L. Kuhl
Summary: The development of versatile, inexpensive, and robust polymer microfluidic chips for serial X-ray crystallography allows for efficient sample delivery and measurements at both synchrotrons and X-ray free electron lasers. The chips offer advantages such as low sample consumption, minimal background scattering, and precise control over sample flow, making them suitable for a wide range of protein crystallography experiments.
Article
Computer Science, Artificial Intelligence
Yazeed Alabdulkarim, Marwan Almaymoni, Shahram Ghandeharizadeh
Summary: Polygraph is a tool designed to quantify application anomalies caused by violating transaction properties. It is a plug-n-play framework with visualization tools for quick integration into existing applications and benchmark testing. Demonstrated using various benchmarks, Polygraph is highlighted as an online tool that scales efficiently for processing transaction logs faster than their production rate.
IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING
(2021)
Article
Engineering, Multidisciplinary
Dingguo Liang, Ying Yang, Rongchang Li, Zhengen Zhao
Summary: This paper studies a robust distributed fault estimation method for interconnected systems with process and measurement disturbances. By designing robust distributed fault estimators, the influence of disturbances on fault estimation errors is constrained, and the conditions for plug-and-play operations are analyzed. Simulation studies on two cases have been conducted to demonstrate the effectiveness of the proposed method.
IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING
(2022)
Article
Operations Research & Management Science
Hyun-Jung Kim, Jun-Ho Lee
Summary: The paper proposes an efficient robot task sequence for a flexible assembly system to minimize cycle time and produce multiple types of products simultaneously.
ANNALS OF OPERATIONS RESEARCH
(2021)
Article
Chemistry, Analytical
Ryota Ushiyama, Keiichiro Koiwai, Hiroaki Suzuki
Summary: In this study, a highly reproducible microfluidics-based method was established to generate monodisperse giant unilamellar vesicles (GUVs) without surface treatment or precise flow-rate adjustment. The success rate of GUV formation reached nearly 100% by stabilizing the oil-water co-flow and adjusting the curvature of the interface. Membrane-protein insertion assay confirmed the unilamellarity of GUVs and their shrinkage caused by osmosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Materials Science, Ceramics
Kai Jiang, Kangsen Li, Gang Xu, Feng Gong, Xiaoyu Wu, Dongfeng Diao, Likuan Zhu
Summary: This study proposes a new method for hot embossing of glass microfluidic channels, using a high-T-g glass mold insert to create flexible and reliable channels. Experimental results demonstrate that the high-T-g glass has good surface quality and high-temperature resistance, making it a suitable material for hot embossing mold inserts.
CERAMICS INTERNATIONAL
(2021)
Article
Computer Science, Information Systems
Daniele Passaretti, Max Steiger, Thilo Pionteck
Summary: Cyber-Physical Systems (CPSs) combine computation, networking, and physical processes. This paper proposes a Centralized Control Unit (CCU) and Communication Infrastructure for CPSs, enabling support for plug-and-play subsystem components. To ensure reliable and flexible communication between components from different vendors, the communication infrastructure is modeled in layers with communication classes. Additionally, three vendor-agnostic application protocols are proposed.
Article
Chemistry, Multidisciplinary
Rujie Sun, Xin Song, Kun Zhou, Yuyang Zuo, Richard Wang, Omar Rifaie-Graham, David J. Peeler, Ruoxiao Xie, Yixuan Leng, Hongya Geng, Giulia Brachi, Yun Ma, Yutong Liu, Lorna Barron, Molly M. Stevens
Summary: This study presents a versatile platform for fabricating fillable microrobots using microfluidic loading and dip sealing (MLDS), which allows for encapsulating different types of cargoes within hollow microrobots and protecting the cargo integrity. The technique is supported by high-resolution 3D printing and an integrated microfluidic loading system, enabling a highly precise loading process and improved cargo loading capacity. The MLDS platform offers new opportunities for targeted drug delivery, environmental sensing, and chemically powered micromotor applications.
ADVANCED MATERIALS
(2023)
Article
Nuclear Science & Technology
M. Pineda, D. Tsaoulidis, P. I. O. Filho, T. Tsukahara, P. Angeli, E. S. Fraga
Summary: This study focuses on the development of an optimization-based design procedure for continuous analysis systems to detect radionuclides in nuclear waste, using microfluidic solvent extraction and online measurement. The importance of using computer-aided optimization procedures in designing microsystems is highlighted.
NUCLEAR ENGINEERING AND DESIGN
(2021)
Article
Chemistry, Multidisciplinary
Dehong Wang, Yingxiang Liu, Jie Deng, Shijing Zhang, Jing Li, Weiyi Wang, Junkao Liu, Weishan Chen, Qiquan Quan, Gangfeng Liu, Hui Xie, Jie Zhao
Summary: This article introduces a miniature amphibious robot based on vibration-driven locomotion mechanism, which features innovative rigid-flexible hybrid modules and fast movements, making it suitable for narrow amphibious environments.
Article
Physics, Applied
Jacob L. Binsley, Stefano Pagliara, Feodor Y. Ogrin
Summary: Integrating miniature pumps within microfluidic devices is crucial for advancing point-of-care diagnostics. This study simulates and evaluates the performance of an elastic-magnetic integrated microfluidic pump, revealing the correlation between the emergence of flow behavior and variables such as frequency and proximity, and providing important insights for the design and optimization of the pump.
JOURNAL OF APPLIED PHYSICS
(2022)
Article
Chemistry, Analytical
Sajad Yazdanparast, Pouya Rezai, Alidad Amirfazli
Summary: A co-flow microfluidic droplet-generation device with flexible walls was developed, allowing for the adjustment of continuous phase channel width to control droplet sizes. Two different droplet-generation regimes were observed at low dispersed phase Weber numbers. Reducing the channel width produced smaller droplets and a wider range of droplet sizes compared to current technology.
Article
Mechanics
A. Alexandre, T. Guerin, D. S. Dean
Summary: The study focuses on Taylor dispersion of tracer particles in microfluidic channels with strong confinement, highlighting the influence of channel walls on diffusivity and interactions with the tracer particles. A simple and general formula is provided for calculating the effective diffusion constant along the channel and the first non-trivial finite time correction, applicable to various flow conditions, interaction potentials, and diffusion tensors. The formulas are particularly useful for numerical implementation and comparison with experiments.
Article
Chemistry, Multidisciplinary
Nan-Nan Deng, Maaruthy Yelleswarapu, Lifei Zheng, Wilhelm T. S. Huck
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2017)
Article
Chemistry, Physical
Jing Zhang, Zhijun Meng, Ji Liu, Christoph Schlaich, Ziyi Yu, Xu Deng
JOURNAL OF MATERIALS CHEMISTRY A
(2017)
Article
Chemistry, Multidisciplinary
Nan-Nan Deng, Mahesh A. Vibhute, Lifei Zheng, Hui Zhao, Maaruthy Yelleswarapu, Wilhelm T. S. Huck
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Article
Chemistry, Multidisciplinary
Chuan-Lin Mou, Wei Wang, Zhi-Lu Li, Xiao-Jie Ju, Rui Xie, Nan-Nan Deng, Jie Wei, Zhuang Liu, Liang-Yin Chu
Article
Nanoscience & Nanotechnology
Jing Zhang, Zhijun Meng, Ji Liu, Su Chen, Ziyi Yu
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Nanoscience & Nanotechnology
Zhi-Jun Meng, Ji Liu, Ziyi Yu, Hantao Zhou, Xu Deng, Chris Abell, Oren A. Scherman
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Nanoscience & Nanotechnology
Shaobo Jin, Xueyong Wei, Ziyi Yu, Juan Ren, Zhijun Meng, Zhuangde Jiang
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Biochemical Research Methods
Nan-Nan Deng
Article
Multidisciplinary Sciences
Amit Nagarkar, Won-Kyu Lee, Daniel J. Preston, Markus P. Nemitz, Nan-Nan Deng, George M. Whitesides, L. Mahadevan
Summary: The experiment demonstrates how symmetry-breaking action in space-time can lead to locomotion of a thin circular sheet, allowing it to walk on land and swim in water. The shape asymmetry of the sheet in different modes of locomotion leads to asymmetric interactions with the environment, resulting in different modes of movement.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Multidisciplinary
Qi-Hong Zhao, Fang-Hao Cao, Zhen-Hong Luo, Wilhelm T. S. Huck, Nan-Nan Deng
Summary: This study successfully achieved photoswitchable molecular transport between programmable membraneless DNA coacervates in synthetic microcompartments using droplet microfluidics, mimicking controlled bi-directional communication inside cells and providing a promising new route for assembling multicompartment artificial cells with functional networks.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Engineering, Chemical
Xu-Chun Song, Zi-Han Zhou, Ya-Lan Yu, Nan-Nan Deng
Summary: A simple microfluidic approach to preparing monodisperse liposomes from oil-in-water droplets is presented, eliminating the need for complex microfluidic devices and tedious manipulation. This method provides a new platform for controllable preparation of liposomes.
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Dong-Yu Li, Wei Wang, Liang-Yin Chu, Nan-Nan Deng
Summary: Tunable structural coloration can be achieved in colorless water-in-oil-in-water double emulsion droplets through total internal reflection and interference at microscale concave interfaces. The shell thickness and eccentricity of the core-shell structures are found to be critical for the formation of iridescent structural colors. Only eccentric thin-shell water-in-oil-in-water droplets exhibit structural colors. Importantly, structural colors based on water-oil interfaces are highly responsive to various environmental stimuli including osmotic pressure, temperature, magnetic fields, and light composition. This work expands the applications of droplet-based structural colors to aqueous systems.
Review
Chemistry, Multidisciplinary
Mu-Yueh Chang, Hirotaka Ariyama, Wilhelm T. S. Huck, Nan-Nan Deng
Summary: The bottom-up construction of a living cell using non-living materials is a major challenge in science and technology. Reproduction of cells into similar offspring is crucial for life, and therefore, building a synthetic cell that can autonomously divide is a fundamental task in bottom-up synthetic biology. In this review, we summarize the strategies of inducing synthetic division using physical, chemical, and biological stimuli, and highlight the future challenges in constructing autonomous synthetic cell division.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Analytical
Zhen Liu, Yingfeng Lei, Ziyi Yu, Zhijun Meng, Shaobo Jin, Xiaoli Qu, Zhuangde Jiang, Fanglin Zhang, Xueyong Wei
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Chemistry, Multidisciplinary
Zhi-Jun Meng, Jing Zhang, Xu Deng, Ji Liu, Ziyi Yu, Chris Abell
MATERIALS HORIZONS
(2019)