Article
Oncology
Andrea Marchetti, Matteo Rosellini, Giacomo Nuvola, Elisa Tassinari, Veronica Mollica, Alessandro Rizzo, Matteo Santoni, Alessia Cimadamore, Andrea Farolfi, Rodolfo Montironi, Stefano Fanti, Francesco Massari
Summary: Prostate cancer remains a significant health issue in men, with new treatment options such as PARP inhibitors and radiometabolic approaches showing promising clinical benefits. The evolving understanding of molecular characteristics in prostate cancer is expanding treatment possibilities, particularly for patients with altered DNA repair genes. Ongoing clinical trials are focused on further exploring and expanding the use of these treatments in advanced prostate cancer.
Article
Neurosciences
Amanda M. Fullerton, Deborah A. Vickers, Robert Luke, Addison N. Billing, David McAlpine, Heivet Hernandez-Perez, Jonathan E. Peelle, Jessica J. M. Monaghan, Catherine M. McMahon
Summary: This study aims to understand the responses and functional connectivity of auditory and visual cortices to speech and non-speech stimuli in postlingually deaf cochlear implant users and found that they show beneficial effects in cross-modal activity. Specifically, an increase in connectivity between the left auditory and visual cortices is positively correlated with their abilities to understand speech in background noise.
Article
Linguistics
Victoria R. Poulton, Mante S. Nieuwland
Summary: Prediction-based theories of language comprehension suggest that listeners predict the meaning and phonological form of upcoming words. Previous studies have shown controversial results regarding the classification and replicability of the phonological prediction-mismatch effect (PMN) in event-related potential (ERP) demonstrations. In this study, we attempted to replicate the PMN effect and differentiate it from the N400 using a larger participant sample. The results revealed negative ERP responses to unpredictable words in both the early and N400 time windows, with no significant scalp distribution differences between the two.
NEUROBIOLOGY OF LANGUAGE
(2022)
Article
Neurosciences
Negin Nadvar, Noelle Stiles, Jeiran Choupan, Vivek Patel, Hossein Ameri, Yonggang Shi, Zhongming Liu, John Jonides, James Weiland
Summary: Resting-state functional connectivity analysis can evaluate the impact of vision loss on brain plasticity. This study found a partial reversal of functional connectivity changes in Argus II retinal prosthesis patients following blindness.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Medicine, General & Internal
Daisuke Sawamura, Yoshinobu Tanabe, Satoshi Sakuraba, Jiahong Cui, Hiroshi Miura, Ryuji Saito, Masaaki Sugi, Akihiro Watanabe, Yukina Tokikuni, Kazuhiro Sugawara, Mitsunori Miyazaki, Reiko Miyamoto, Shinya Sakai
Summary: This study investigated the impact of cross-modal conflicts between auditory and visual stimuli on working memory tasks and brain activities. The results showed that visual cross-modal conflict significantly impairs auditory working memory task performance, regardless of the presence of semantic or nonsemantic distractors. The right ventrolateral prefrontal cortex may play a crucial role in inhibiting visual nonsemantic information in cross-modal conflict situations, and the bilateral inferior parietal cortex may be closely associated with the inhibition of visual cross-modal distractors.
Article
Substance Abuse
Iain McPhee, Barry Sheridan, Andrew Horne, Steph Keenan, Fiona Houston
Summary: This study provides data on substance use among young people in Scotland, aiming to inform policy and practices for a group who do not typically access specialized alcohol and drug services. The study found that the substance use patterns of the respondents differed from those who currently use specialist services. The most commonly used substances were cannabis and cocaine. The study also identified a lack of knowledge on how and where to seek help for substance use problems among the respondents.
DRUGS HABITS AND SOCIAL POLICY
(2022)
Article
Engineering, Biomedical
Jichi Chen, Hong Wang, Enqiu He
Summary: Driving under unfavorable driving state is the primary cause of road accidents. To address this issue, a framework combining model-driven and data-driven approaches is proposed, using EEG recordings and a customized CNN model. The framework achieves excellent results in UDS detection.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2023)
Article
Thermodynamics
Hu Hao, Biao Hao, Weihang Kong, Jiliang Chen, Xiaodan Zhang
Summary: This study presents the design and development of an integrated optical-electrical coaxial cross-modal probe sensor (IOECCMPS) for measuring phase volume fraction in oil-water-gas flow. The results demonstrate that the IOECCMPS is capable of accurately measuring the phase volume fraction in multi-phase flows, providing valuable insights for oil production monitoring technology.
EXPERIMENTAL THERMAL AND FLUID SCIENCE
(2024)
Article
Chemistry, Applied
Yaxing Guo, Juntao Wang, Weihua Liu, Jiajia Liu, Chun Wang, Qiuhua Wu, Zhi Wang
Summary: A novel magnetic material was developed for efficient extraction of trace plant growth regulators from water and food samples. The established method, combined with high performance liquid chromatography-fluorescence detection, showed good linearity, accuracy, and precision. The results demonstrate that this method is sensitive and efficient for the determination of PGRs in real samples.
Article
Chemistry, Physical
Jennifer A. Clark, Erik E. Santiso
Summary: This work presents predictive combining rules within the SAFT-gamma-Mie framework by deriving them from density functional theory calculations of molecular fragments. The resulting model accounts for various effects such as ionization energies, partial charges, dipole moments, and quadrupole moments, leading to realistic cross-interaction energies without the need for experimental data. Good qualitative agreement was obtained for phase equilibria calculations of various binary mixtures, showing the potential of the proposed methodology.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Hospitality, Leisure, Sport & Tourism
Igor O. Garnov, Tatyana P. Loginova, Nina G. Varlamova, Natalya N. Potolitsyna, Alexey A. Chernykh, Evgeniy R. Bojko
Summary: The study found that the comprehensive program during the summer-autumn training period helps improve the functional status of professional Russian cross-country skiers, enhancing physical power, endurance, upper limb strength, and speed on roller skis, as well as promoting faster and more complete recovery of physiological and biochemical parameters.
PEDAGOGY OF PHYSICAL CULTURE AND SPORTS
(2021)