期刊
HEARING RESEARCH
卷 303, 期 -, 页码 1-11出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.heares.2012.10.010
关键词
-
资金
- Royal Society University Research Fellowship [516002.K5746.KK]
- BBSRC [BB/D009669/1]
- Deafness Research UK [561:UEL:DJ]
- BBSRC [BB/D009669/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/D009669/1] Funding Source: researchfish
- Rosetrees Trust [M58-F1] Funding Source: researchfish
Despite their curious morphology prompting numerous hypotheses of their normal function, the root cells lining the cochlear outer sulcus have long evaded physiological characterization. A growing body of evidence now suggests that they regulate the solute content of the endolymph and/or the perilymph, and may be essential in safe-guarding the global homeostasis of the cochlea. Immuno-labeling experiments have demonstrated polarized expression of key ion transport proteins, and recent electrophysiological recordings have identified specific membrane conductances. These studies have painted a clearer picture of how this unusual cell type may contribute to the maintenance of sound transduction, and how they may be central to pathological processes associated with various forms of hearing loss. This article is part of a Special Issue entitled Annual Reviews 2013. (C) 2012 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据