Article
Endocrinology & Metabolism
Iris Lee, Julia Vresilovic, Maryam Irfan, Robert Gallop, Anuja Dokras
Summary: The study found that there is a difference in the risk of metabolic syndrome in women with polycystic ovary syndrome between Black and White women, with Black women having a higher incidence rate. In addition to early cardiometabolic screening at the time of diagnosis, this population also requires ongoing and frequent screening.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Public, Environmental & Occupational Health
Xiao-Qin Wang, Xiao-Han Ren, Wen-Jing Kou, Yang Li, Zhao-Zhao Hui, Jia-Ru Sun, Ming-Xu Wang
Summary: This study found a positive association between housework and metabolic markers in women, including triglycerides, metabolic syndrome, and pre-hypertension. However, this relationship was not observed in men for any biomarkers considered. One possible explanation is that people who engage in high-intensity housework are more stressed and sleep less, which could be a mechanism by which housework becomes associated with metabolic disease.
Article
Endocrinology & Metabolism
Jiwon Kwak, In-Ho Seo, Yong-Jae Lee
Summary: In this study, we examined the relationship between serum GGT levels and the risk of developing MetS. Higher GGT levels were associated with an increased risk of MetS, and this association was stronger in men compared to women.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Medicine, Research & Experimental
Maryam Farahmand, Maryam Rahmati, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: This study compared the effect of breastfeeding (BF) in women with and without gestational diabetes mellitus (GDM) on metabolic syndrome (MetS) incidence. The findings showed that BF, especially exclusive BF, has a protective effect on MetS incidence risk, and it is more effective in reducing the risk of MetS among women with a history of GDM.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Nutrition & Dietetics
Anna Maria Cybulska, Daria Schneider-Matyka, Mateusz Bosiacki, Dariusz Chlubek, Mariusz Panczyk, Elzbieta Grochans
Summary: This study evaluated the relationship between element levels and the risk of metabolic syndrome in perimenopausal women. The results showed that low blood potassium levels were associated with an increased risk of metabolic syndrome, while higher copper levels were observed in overweight women, negatively correlating with total cholesterol, LDL, and systolic blood pressure.
Article
Psychology, Clinical
Camille Souama, Yuri Milaneschi, Femke Lamers, Christiaan H. Vinkers, Erik J. Giltay, Edith J. Liemburg, Brenda W. J. H. Penninx
Summary: Childhood trauma is associated with the development of metabolic syndrome over time. This association is related to the biological risk factors for cardiometabolic disease and is unaffected by lifestyle.
PSYCHOLOGICAL MEDICINE
(2023)
Review
Biochemistry & Molecular Biology
Vania Miloucheva Peneva, Dora Dimitrova Terzieva, Mitko Dimitrov Mitkov
Summary: Metabolic syndrome (MetS) is a combination of cardiometabolic risk factors that increase the chances of developing type 2 diabetes, cardiovascular diseases, and death. In women, an insulin-resistant state associated with polycystic ovarian syndrome and increased intra-abdominal fat deposition promotes the development of MetS and increases cardiovascular risk. The hormone melatonin, which is regulated by the suprachiasmatic nucleus, plays a role in this process. The relationship between melatonin and the main features of MetS in women, including glucose metabolism, lipid disturbances, hypertension, and vascular dysfunction, is discussed in this review.
Editorial Material
Endocrinology & Metabolism
Anju E. Joham, Helena J. Teede
Summary: A new paper investigates the genetic risk factors for PCOS and non-reproductive PCOS phenotypes, concluding that PCOS is a metabolic disorder and that ovarian function is not necessary for its cardiometabolic features. The study also highlights the implications of PCOS for both men and women.
NATURE REVIEWS ENDOCRINOLOGY
(2022)
Review
Food Science & Technology
Jing Yang, Huayi Suo, Jiajia Song
Summary: MitoQ reduces mitochondrial oxidative stress and promotes autophagy and mitochondrial biogenesis to alleviate MetS symptoms such as obesity, insulin resistance, hypertension, and cardiovascular disease. Its regulatory effect on mitochondrial homeostasis is mediated through AMPK and its downstream signaling pathways.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Review
Endocrinology & Metabolism
Lucas Bandeira Marchesan, Ramon Bossardi Ramos, Poli Mara Spritzer
Summary: The metabolic profiles of women with PCOS in Latin America are worse than those without PCOS in the same region, with higher anthropometric and metabolic parameters. Further studies evaluating metabolic comorbidities and distinct PCOS phenotypes in different Latin American countries are needed for primary and secondary prevention of PCOS in the region.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Nutrition & Dietetics
Emily Riseberg, Kenneth Chui, Katherine A. James, Rachel Melamed, Tanya L. Alderete, Laura Corlin
Summary: The association between manganese and metabolic syndrome is unclear. This study found a potential beneficial effect of manganese on diabetic markers, but no evidence of an association with incident metabolic syndrome.
Review
Nutrition & Dietetics
Fernanda Martins de Albuquerque, Milene Cristine Pessoa, Mariana De Santis Filgueiras, Danielle Soares Gardone, Juliana Farias de Novaes
Summary: This study evaluated the evidence on longitudinal associations between objectively measured retail food outlets and metabolic syndrome components. The findings suggest limited evidence for such associations, highlighting the need for further research to better understand the influence of the community food environment on metabolic syndrome.
Article
Cell Biology
Pernille B. Udesen, Anja E. Sorensen, Rikke Svendsen, Nanna L. S. Frisk, Anne L. Hess, Mubeena Aziz, Marie Louise M. Wissing, Anne Lis M. Englund, Louise T. Dalgaard
Summary: In a 6-year follow-up study, it was found that the levels of certain miRNAs in women with PCOS changed, indicating a shift towards a less hyperandrogenic profile. These findings contribute to our understanding of PCOS and provide potential biomarkers for future research.
Article
Pediatrics
Esther M. Gonzalez-Gil, Augusto Anguita-Ruiz, Anton Kalen, Carmela De las Lamas Perez, Azahara Ruperez, Rocio Vazquez-Cobela, Katherine Flores, Angel Gil, Mercedes Gil-Campos, Gloria Bueno, Rosaura Leis, Concepcion M. Aguilera
Summary: Puberty is a stage of considerable metabolic risk, especially for those with obesity. The low-grade systemic inflammatory status associated with obesity could be a connection with metabolic syndrome (MetS). Evaluating cardiometabolic and inflammatory status in children with obesity at an early stage is crucial in preventing future comorbidities. Children with obesity and high concentrations of total plasminogen activator inhibitor-1 (tPAI) have higher odds of developing MetS in the future.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Endocrinology & Metabolism
Ahmed Torky, Ninet Sinaii, Smita Jha, Jay Desai, Diala El-Maouche, Ashwini Mallappa, Deborah P. Merke
Summary: Patients with CAH have a higher prevalence of obesity, hypertension, insulin resistance, fasting hyperglycemia, and dyslipidemia during childhood and adulthood compared to the general US population, indicating an early onset of metabolic morbidity in this population. Treatment-related and familial factors play a role in the development of these metabolic conditions.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Psychology, Developmental
Sara Sammallahti, Elisa Holmlund-Suila, Runyu Zou, Saara Valkama, Jenni Rosendahl, Maria Enlund-Cerullo, Helena Hauta-Alus, Marius Lahti-Pulkkinen, Hanan El Marroun, Henning Tiemeier, Outi Makitie, Sture Andersson, Katri Raikkonen, Kati Heinonen
Summary: Higher maternal vitamin D concentration during pregnancy is associated with better child mental health, particularly in relation to negative affectivity, a trait indicating increased risk of psychopathology. The study found that higher maternal early/mid-pregnancy vitamin D levels were associated with lower negative affectivity in infants, while cord blood vitamin D levels showed less clear associations. These findings suggest that maternal vitamin D status during early- and mid-pregnancy may play a role in the behavioral development of offspring.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Review
Pediatrics
Rachel Robinson, Polina Girchenko, Anna Pulakka, Kati Heinonen, Anna Lahdepuro, Marius Lahti-Pulkkinen, Petteri Hovi, Marjaana Tikanmaki, Peter Bartmann, Aulikki Lano, Lex W. Doyle, Peter J. Anderson, Jeanie L. Y. Cheong, Brian A. Darlow, Lianne J. Woodward, L. John Horwood, Marit S. Indredavik, Kari Anne Evensen, Neil Marlow, Samantha Johnson, Marina Goulart de Mendonca, Eero Kajantie, Dieter Wolke, Katri Raikkonen
Summary: This study examined the differences in ADHD symptoms and diagnosis between preterm and term-born adults and found that while preterm adults may not report higher levels of ADHD symptoms, they have a higher risk of receiving an ADHD diagnosis in adulthood.
PEDIATRIC RESEARCH
(2023)
Article
Psychology, Developmental
Anna Lahdepuro, Marius Lahti-Pulkkinen, Riikka Pyhala, Soile Tuovinen, Jari Lahti, Kati Heinonen, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Eero Kajantie, Polina Girchenko, Katri Raikkonen
Summary: The study found that positive maternal mental health during pregnancy is associated with a reduced risk of mental and behavioral disorders in children. This association is also seen in children of mothers facing mental health issues.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Psychology, Social
Sointu Leikas, Marius Lahti-Pulkkinen, Katri Raikkonen
Summary: This study investigated the effects of parenthood on mothers' personality development and found that mothers experienced changes in neuroticism and extraversion from early pregnancy to 6 months post-partum. Furthermore, mother-perceived child difficult temperament attenuated desirable personality change and amplified the increases in impulsivity.
EUROPEAN JOURNAL OF PERSONALITY
(2023)
Article
Health Care Sciences & Services
Linda C. Gallo, Addie L. Fortmann, Taylor L. Clark, Scott C. Roesch, Julia I. Bravin, Samantha Spierling R. Bagsic, Haley Sandoval, Kimberly L. Savin, Todd Gilmer, Gregory A. Talavera, Athena Philis-Tsimikas
Summary: This study tested the effectiveness of a culturally appropriate care transitions program for Latino adults with multiple cardiometabolic conditions and behavioral health concerns. The program did not reduce hospital utilization or improve patient-reported outcomes.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Biochemistry & Molecular Biology
Jolien Rijlaarsdam, Marta Cosin, Laura Schellhas, Sarina Abrishamcar, Anni Malmberg, Alexander Neumann, Janine F. Felix, Jordi Sunyer, Kristine B. Gutzkow, Regina Grazuleviciene, John Wright, Mariza Kampouri, Heather J. Zar, Dan J. Stein, Kati Heinonen, Katri Raikkonen, Jari Lahti, Anke Huels, Doretta Caramaschi, Silvia Alemany, Charlotte A. M. Cecil
Summary: The general psychopathology factor (GPF) has been proposed as a way to capture variance shared between psychiatric symptoms. In this study, epigenome-wide meta-analyses were conducted to identify associations of DNA methylation (DNAm) with school-age general psychopathology, revealing evidence of an association between DNAm at school-age and GPF.
MOLECULAR PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Suvi Alenius, Eero Kajantie, Reijo Sund, Markku Nurhonen, Peija Haaramo, Pieta Nasanen-Gilmore, Sakari Lemola, Katri Raikkonen, Daniel D. Schnitzlein, Dieter Wolke, Mika Gissler, Petteri Hovi
Summary: Attendance in special education is more common among individuals born preterm. However, the minor differences in school grades according to gestational age do not translate into educational differences in young adulthood.
SCIENTIFIC REPORTS
(2023)
Review
Psychology, Clinical
Taylor L. Clark, Kimberly L. Savin, Perla Perez-Ramirez, Tania Valdez, Gloria Toba, Linda C. Gallo
Summary: This review examines the effectiveness of eHealth weight loss interventions for adults with low income and the strategies used to tailor them. The results suggest that eHealth interventions can lead to modest weight reductions, but the evidence is limited. Further research is needed to determine the effectiveness of eHealth interventions in this population.
Article
Medicine, General & Internal
Marco Bucci, Patricia Iozzo, Harri Merisaari, Ville Huovinen, Heta Lipponen, Katri Raikkonen, Riitta Parkkola, Minna Salonen, Samuel Sandboge, Johan Gunnar Eriksson, Lauri Nummenmaa, Pirjo Nuutila
Summary: This study aimed to investigate the effects of maternal obesity on brain structure and metabolism in frail women and their reversibility in response to exercise. The results showed that offspring of lean/normal-weight mothers had higher white matter density compared to offspring of obese/overweight mothers. Exercise intervention resulted in an increase in white matter density, with a greater effect observed in offspring of lean/normal-weight mothers. These findings suggest that exercise has an impact on brain morphology and cognition in elderly frail women.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Samuel Sandboge, Katri Raikkonen, Marius Lahti-Pulkkinen, Helena Hauta-alus, Elisa Holmlund-Suila, Polina Girchenko, Eero Kajantie, Outi Makitie, Sture Andersson, Kati Heinonen
Summary: This study found that high-dose (1200 IU) vitamin D-3 supplementation during the first 2 years reduced the risk of internalizing problems in children aged 6 to 8 years, especially in those with lower maternal vitamin D-3 levels.
Article
Pediatrics
Ingrid Marie Husby Hollund, Kristina Anna Djupvik Aakvik, Silje Dahl Benum, Sigrid Hegna Ingvaldsen, Stian Lydersen, Marjaana Tikanmaki, Petteri Hovi, Katri Raikkonen, Eero Kajantie, Samantha Johnson, Neil Marlow, Nicole Baumann, Dieter Wolke, Marit S. Indredavik, Kari Anne I. Evensen
Summary: The associations between mental health, pain, and tiredness in adults are independent of gestation or birthweight. Further research should explore other potential mechanisms to explain the increased risk of mental health problems in the preterm population.
Article
Multidisciplinary Sciences
Lourdes R. R. Guerrero, Suzi Hong, Wassim Tarraf, Krista Perreira, Alvaro Camacho, Jordan N. N. Kohn, Daniel E. E. Jimenez, Gregory A. A. Talavera, Linda Gallo, Matthew A. A. Allison, Sylvia Wassertheil-Smoller, Hector M. M. Gonzalez
Summary: This study examined the association between anxiety and depressive symptoms with hsCRP levels in a diverse Hispanic/Latino population, and found a positive correlation between anxiety, depressive symptoms, and hsCRP levels. However, this association was not significant after considering cardiovascular disease risk factors and medications.
Article
Cardiac & Cardiovascular Systems
Kyndaron Reinier, Jee-Young Moon, Harpriya S. Chugh, Arayik Sargsyan, Kotoka Nakamura, Faye L. Norby, Audrey Uy-Evanado, Gregory A. Talavera, Linda C. Gallo, Martha L. Daviglus, Katy Hadduck, Daniel Shepherd, Angelo Salvucci, Robert C. Kaplan, Sumeet S. Chugh
Summary: This study provides population-based evidence on risk factors for sudden cardiac arrest (SCA) among Hispanic or Latino adults. It shows that chronic kidney disease is the strongest risk factor for SCA in this population, followed by established cardiovascular disease.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Psychology, Developmental
Anna Lahdepuro, Marius Lahti-Pulkkinen, Polina Girchenko, Pia M. Villa, Kati Heinonen, Jari Lahti, Riikka Pyhala, Hannele Laivuori, Eero Kajantie, Katri Raikkonen
Summary: Positive maternal mental health during pregnancy has a positive impact on children's psychiatric problems. This study found that higher positive maternal mental health scores during pregnancy were associated with lower total psychiatric problem scores in both early and late childhood.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Oncology
Margaret S. Pichardo, Catherine M. Pichardo, Gregory A. Talavera, Linda C. Gallo, Charlene C. Kuo, Sheila F. Castaneda, Earle C. Chambers, Martha L. Daviglus, Amber Pirzada, Krista M. Perreira, Daniela Sotres-Alvarez, Tania Yadhira Pena Ortiz, Jesse J. Plascak
Summary: This study examines the association between neighborhood socioeconomic factors and cancer preventive behaviors, finding that neighborhood deprivation is negatively associated with adherence to cancer prevention guidelines while gentrification is positively associated with dietary recommendations.
CANCER RESEARCH COMMUNICATIONS
(2023)