Article
Oncology
Jana Mekis, Primoz Strojan, Dusan Mekis, Irena Hocevar Boltezar
Summary: The study aimed to track the changes in voice quality for two years after radiotherapy (RT) for early glottic cancer. The results showed that only a minority of patients had a normal voice two years post-RT, mainly due to post-RT changes in the larynx, such as fibrosis and scarring of the vocal folds.
Article
Otorhinolaryngology
Chin-Hsuan Liu, Pei-Ju Chien, Li-Ting Hung, Li-Mei Wang, Ya-Chuan Kao, Yueh-Ju Tsai, Pen-Yuan Chu
Summary: The modified type III cordectomy has been proven to be an oncologically safe method with satisfactory voice outcomes after long-term follow-up in selected cases of early glottic cancer.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Article
Otorhinolaryngology
Taner Yilmaz
Summary: T-1a glottic cancer can be treated with TLM or RT. Dysphonia is a major drawback of TLM, while voice preservation is considered a key advantage of RT. Studies on the voice outcomes of both treatment options have conflicting results but suggest a tendency towards better voice outcomes after TLM compared to the past.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Otorhinolaryngology
Maarten C. Dorr, Aniel Sewnaik, Elrozy Andrinopoulou, Diako Berzenji, Emilie A. C. Dronkers, Simone E. Bernard, Arta Hoesseini, Lisa Tans, Dimitris Rizopoulos, Robert J. Baatenburg de Jong, Marinella P. J. Offerman
Summary: This study aimed to investigate the longitudinal trajectories for patient-reported voice quality after treatment for early-stage glottic cancer and identify associated risk factors. The results showed that different treatment modalities resulted in varying degrees of improvement in voice quality, but no significant differences were found in long-term outcomes.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Otorhinolaryngology
Maarten C. C. Dorr, Eleni-Rosalina Andrinopoulou, Aniel Sewnaik, Diako Berzenji, Kira S. S. van Hof, Emilie A. C. Dronkers, Simone E. E. Bernard, Arta Hoesseini, Dimitirs Rizopoulos, Robert J. Baatenburg J. de Jong, Marinella P. J. Offerman
Summary: This study aims to develop an individualized dynamic prediction model for patient-reported voice quality. The study found that the model can provide individualized predictions at every time point and can be used throughout the follow-up period. Increasing the number of measurements during prediction improves predictive performance, while adding more clinical and demographic variables does not provide better predictions.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Otorhinolaryngology
Beyhan Ceylaner Bicakci, Teuta Zoto Mustafayev, Oguz Cetinayak, Sefik Igdem, Sumerya Duru Birgi, Deniz Meydan, Fatih Demircioglu, Banu Atalar, Enis Ozyar, Fadime Akman
Summary: This study retrospectively analyzed the clinical outcomes of patients with early stage laryngeal cancer treated with carotid sparing intensity-modulated radiotherapy. The results showed excellent oncologic outcomes and acceptable side effects. Longer follow-up is needed to evaluate the long-term effect on stroke.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Review
Oncology
Amit Gupta, Kee Howe Wong, Kate Newbold, Shreerang Bhide, Chris Nutting, Kevin Joseph Harrington
Summary: Early-stage squamous cell cancer of the glottis has a good prognosis, but radiotherapy may lead to late toxicities. Current research focuses on the radiation dose received by carotid arteries and the risk of cerebrovascular events. Motion has limited the reduction of radiation treatment volume.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, Research & Experimental
Patrick O. McGarey, Ryan Bitar, Charlotte K. Hughes, Noah Hodson, Edward A. Harris, Laura M. Dominguez, Gregory R. Dion, C. Blake Simpson
Summary: This study aimed to investigate the relationship between the glottic gap area and severity of presbyphonia in relation to patient-reported outcomes and stroboscopic findings. The results showed that patients with presbyphonia had a larger glottic gap area and greater open-phase quotient on stroboscopy, but these metrics did not correlate with patient-reported vocal function or the presence of secondary muscle tension dysphonia (MTD). This suggests that dysphonia severity in presbyphonia is not solely explained by glottic gap or MTD.
Article
Otorhinolaryngology
Lucia Stanikova, Karol Zelenik, Martin Formanek, Jana Seko, Radana Walderova, Peter Kantor, Pavel Kominek
Summary: Voice quality evolution post-TLC depends on the extent of surgery, with no significant improvement at 6 weeks post-surgery. Improvements in less extensive cordectomies occur between 6 weeks and 6 months post-surgery. Understanding the progression of voice quality over time is crucial for counseling patients considering phonosurgical procedures.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Otorhinolaryngology
Dursun Mehmet Mehel, Abdulkadir Ozgur, Nilgun Sahin, Asli Aybuke Vural, Tugba Yemis, Mehmet Celebi, Samet Aydemir, Dogukan Ozdemir, Gokhan Akgul
Summary: In early-stage glottic carcinoma patients, there was no significant difference in voice quality between radiotherapy and microsurgical cordectomy, with emotional and physiological scores significantly higher in the MC group and no significant difference found in functional scores.
ENT-EAR NOSE & THROAT JOURNAL
(2021)
Article
Oncology
Pihla Pakkanen, Heikki Irjala, Taru Ilmarinen, Elina Halme, Paula Lindholm, Antti Makitie, Tuija Wigren, Leena-Maija Aaltonen
Summary: This study compared the outcomes of transoral laser surgery (TLS) and radiation therapy (RT) in patients with glottic T1a laryngeal squamous cell carcinoma (LSCC). The study found that the oncological outcomes of both treatment modalities were similar.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2022)
Article
Oncology
Chen-Chi Wang, Wen-Jiun Lin, Jing-Jie Wang, Chien-Chih Chen, Kai-Li Liang, Yen-Jung Huang
Summary: Transoral robotic surgery (TORS) has shown promising results in the treatment of glottic cancer involving the anterior commissure (AC). It provides better exposure and can be used as a minimally invasive approach in patients with radiation failure to preserve the organ.
FRONTIERS IN ONCOLOGY
(2022)
Article
Medicine, Research & Experimental
Philipp Reinhardt, Roland Giger, Eberhard Seifert, Mohamed Shelan, Elena Riggenbach, Dario Terribilini, Andreas Joosten, Daniel H. Schanne, Daniel M. Aebersold, Peter Manser, Matthias S. Dettmer, Christian Simon, Esat M. Ozsahin, Raphael Moeckli, Andreas Limacher, Francesca Caparrotti, Deepa Nair, Jean Bourhis, Martina A. Broglie, Abrahim Al-Mamgani, Olgun Elicin
Summary: This study aims to compare the efficacy of single vocal cord irradiation (SVCI) and transoral CO2-laser microsurgical cordectomy (TLM) in treating early-stage glottic cancer (ESGC). The study will assess voice quality and other indicators to improve decision-making in the treatment of ESGC.
Article
Medicine, Research & Experimental
Rohith S. Voora, Bharat Panuganti, Mitchell Flagg, Abhishek Kumar, Alexander S. Qian, Nikhil V. Kotha, Edmund M. Qiao, Philip A. Weissbrod, Brent Rose, Ryan K. Orosco
Summary: Transoral laser microsurgery (TLM) is commonly used for early glottic cancer, and most patients do not require additional salvage therapy after TLM. For those who do require salvage therapy, there is no decrease in overall survival or cancer-specific survival.
Article
Otorhinolaryngology
Jacob T. Cohen, Tal Goldman, Miki Paker, Eran Fridman
Summary: The study aimed to examine the correlation between surgeon-reported depth of resection during transoral laser cordectomy for early glottic cancer and depth of resection defined by pathology specimens using staining techniques. The results showed that surgeons' estimations did not align with the staining techniques in determining depth of resection.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2022)
Review
Clinical Neurology
Anna L. Wrobel, Anuradhi Jayasinghe, Samantha E. Russell, Wolfgang Marx, Luis Alameda, Olivia M. Dean, Sue M. Cotton, Michael Berk, Alyna Turner
Summary: The review examined the impact of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for individuals with bipolar disorder. The findings suggested that childhood trauma may be associated with greater improvement in global functioning but not necessarily with treatment response. The overall quality of the evidence was deemed low, highlighting the need for further research to explore the role of childhood trauma in the treatment of bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Health Care Sciences & Services
Z. Liao, K. Allott, J. F. Anderson, E. Killackey, S. M. Cotton
Summary: This study identified three distinct subgroups of young people with first episode psychosis based on their quality of life profiles. One subgroup had good quality of life across all domains, another had poor quality of life particularly in Psychological and Social relationships domains, while the third 'intermediate' group had comparatively low Psychological quality of life. Depression, semantic verbal fluency, social inclusion, and social/occupational functioning were associated with group membership.
QUALITY OF LIFE RESEARCH
(2022)
Article
Psychiatry
Sarah E. Herniman, Stephen J. Wood, Susan M. Cotton, Kelly A. Allott, Christopher Davey, Michael Berk, Lisa J. Phillips
Summary: This study aimed to characterize and compare the profile and network of depressive symptoms in recent-onset schizophrenia spectrum disorders (SSD) and major depressive disorder (MDD) without psychotic features. The findings revealed differences in the profile and relative importance of individual depressive symptoms between SSD and MDD. While sadness was a primary hallmark of depression in both disorders, SSD patients were more likely to experience increased sleep, lower lassitude, and pessimism. The network analysis further identified additional important symptoms in SSD, including lassitude, sleep, appetite, concentration difficulties, and inability to feel.
SCHIZOPHRENIA RESEARCH
(2022)
Article
Psychiatry
Kate Filia, Caroline X. Gao, Henry J. Jackson, Jana Menssink, Amity Watson, Andrew Gardner, Sue M. Cotton, Eoin Killackey
Summary: This study aimed to refine and reduce the Filial Social Inclusion Measure (F-SIM) and evaluate its psychometric properties. The F-SIM was reduced from 135 items to 16 items and showed sound psychometric properties. The F-SIM16 is a reliable and brief self-report measure of social inclusion suitable for clinical and research settings.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2022)
Article
Psychiatry
Andrew M. Chanen, Jennifer K. Betts, Henry Jackson, Sue M. Cotton, John Gleeson, Christopher G. Davey, Katherine Thompson, Sharnel Perera, Victoria Rayner, Holly Andrewes, Louise McCutcheon
Summary: Effective early intervention for young people with BPD does not necessarily rely on specialist psychotherapy, but does require youth-oriented clinical case management and psychiatric care. A dedicated early intervention BPD service model (HYPE), with or without individual psychotherapy, achieved greater treatment attendance and completion, meeting service user, family, and community expectations of care.
Review
Psychology, Multidisciplinary
Greg Smith, Noelle Robertson, Sue Cotton
Summary: This study explores the opportunities for gender affirmation for TGNC individuals through their coping experiences with minority stress. Results show that coping responses for TGNC individuals can support psychological affirmation through defining their own gender identity, fostering self-belief, using information and knowledge, drawing upon other identities, as well as social affirmation through connecting with the TGNC community, cultivating allies, advocating for change, asserting oneself.
Article
Health Care Sciences & Services
Andrew Gumley, Simon Bradstreet, John Ainsworth, Stephanie Allan, Mario Alvarez-Jimenez, Maximillian Birchwood, Andrew Briggs, Sandra Bucci, Sue Cotton, Lidia Engel, Paul French, Reeva Lederman, Shon Lewis, Matthew Machin, Graeme MacLennan, Hamish McLeod, Nicola McMeekin, Cathy Mihalopoulos, Emma Morton, John Norrie, Frank Reilly, Matthias Schwannauer, Swaran P. Singh, Suresh Sundram, Andrew Thompson, Chris Williams, Alison Yung, Lorna Aucott, John Farhall, John Gleeson
Summary: The study investigates the feasibility of a digital intervention in recognizing and managing early warning signs of relapse in schizophrenia to prevent relapse.
HEALTH TECHNOLOGY ASSESSMENT
(2022)
Article
Psychiatry
Laura S. van Velzen, Yara J. Toenders, Akhil Kottaram, Belinsha Youzchalveen, Vita Pilkington, Sue M. Cotton, Abi Brooker, Ben McKechnie, Simon Rice, Lianne Schmaal
Summary: Prediction of suicide attempts during mental health care for young people is moderately accurate, and individual risk factors for suicidal behavior during care can be identified.
CRISIS-THE JOURNAL OF CRISIS INTERVENTION AND SUICIDE PREVENTION
(2023)
Article
Psychiatry
Kieran M. O'Gorman, Lianne Schmaal, Aswin Ratheesh, George Habib, Orania Tokatlidis, Jennifer Jackson-Simpson, Sue M. Cotton, Simon M. Rice
Summary: This study investigated the clinical characteristics of tertiary students and non-students attending a specialist clinic for severe mood disorders. The results showed that compared to non-students, tertiary students reported more severe depressive symptomatology, were more likely to experience suicidal ideation at intake and during treatment, and were more likely to be living separately from their family of origin but less likely to have experienced parental separation. Furthermore, 21.73% of tertiary students dropped out or deferred study during care.
AUSTRALASIAN PSYCHIATRY
(2023)
Article
Psychiatry
Andrew Thompson, Joanna Fitzsimons, Eoin Killackey, Susannah Ahern, Paul Amminger, Mario Alvarez-Jimenez, Michael Berk, Sue Cotton, John McNeil, Patrick McGorry, Barnaby Nelson, Brian O'Donoghue, Aswin Ratheesh, Debra Rickwood, Alison Yung, Stephen Wood
Summary: The field of early psychosis has expanded rapidly over the past few decades with a strong evidence base. However, there is a need for early psychosis services to consistently provide higher quality care. The establishment of the Australian Early Psychosis Collaborative Consortium (AEPCC) aims to address this through the implementation of a clinical research infrastructure.
AUSTRALASIAN PSYCHIATRY
(2023)
Article
Psychiatry
Sue M. Cotton, Kate M. Filia, Matthew P. Hamilton, Caroline X. Gao, Jana M. Menssink, Nic Telford, Patrick McGorry, Debra Rickwood
Summary: This research program in Australia aims to address the lack of routine outcome measures and understanding of complexity and heterogeneity in youth mental health service research. The study identifies better routine outcome measures designed for young people aged 12-25, taking into account their developmental nuances and being meaningful to both young people and service providers. These measures, alongside new tools for assessing complexity and heterogeneity, will help service providers meet the needs of young people with mental health problems.
AUSTRALASIAN PSYCHIATRY
(2023)
Article
Psychiatry
John Gleeson, Ashleigh Lin, Peter Koval, Liza Hopkins, Paul Denborough, Reeva Lederman, Helen Herrman, Sarah Bendall, Dina Eleftheriadis, Sue Cotton, Yael Perry, Michael Kaess, Mario Alvarez-Jimenez
Summary: This study evaluated the effectiveness of a web-based intervention for family carers of youth recovering from early psychosis. The intervention did not show significant effects in reducing perceived stress, but the frequency of use was associated with reductions in stress and improvements in social support. Further improvements are needed in problem-solving, communication, and self-care outcomes.
JMIR MENTAL HEALTH
(2023)
Article
Neurosciences
Samantha E. Russell, Anna L. Wrobel, Melanie M. Ashton, Alyna Turner, Mohammadreza Mohebbi, Michael Berk, Sue Cotton, Seetal Dodd, Chee H. Ng, Gin S. Malhi, Olivia M. Dean
Summary: This study aimed to investigate the impact of post-traumatic stress disorder on treatment outcomes in patients with bipolar disorder. The results showed no significant differences in symptoms and functioning between patients with bipolar disorder alone and those with comorbid bipolar disorder and post-traumatic stress disorder.
CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
(2023)
Article
Substance Abuse
Sue M. Cotton, Sonia Sharmin, Caroline X. Gao, Ellie Brown, Jana M. Menssink, Debra Rickwood, Gillinder Bedi, Ian Hickie, Sarah E. Hetrick, Alexandra G. Parker, Helen Herrman, Nic Telford, Patrick D. McGorry, Kate M. Filia
Summary: This study aimed to investigate the rates and correlates of tobacco use in Australian youth with mental illness at their first presentation to primary mental health services. The results showed that nearly a quarter of young people with mental illness had used tobacco in the past 3 months. Age, gender, relationship status, and poorer functioning were predictors of tobacco use in adolescents, whereas living in a regional location and not studying were predictors in young adults. Having a diagnosed mental illness other than depression and/or anxiety predicted tobacco use in both age groups.
NICOTINE & TOBACCO RESEARCH
(2023)
Article
Psychiatry
Sue M. Cotton, Matthew P. Hamilton, Kate Filia, Jana M. Menssink, Lidia Engel, Cathrine Mihalopoulos, Debra Rickwood, Sarah E. Hetrick, Alexandra G. Parker, Helen Herrman, Nic Telford, Ian Hickie, Patrick D. McGorry, Caroline X. Gao
Summary: This study aimed to explore the utility of quality of life as an outcome measure in youth-specific primary mental health care settings. The findings revealed distinct groups based on levels of impairment in quality of life and identified demographic and clinical differences among these groups.
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2022)
