Article
Multidisciplinary Sciences
Kyle R. Lennon, Gareth H. McKinley, James W. Swan
Summary: The development of data-driven models for complex fluid mechanics is essential for designing soft materials. This study presents a framework that allows rheologists to construct learnable models incorporating important physical information, without being dependent on specific experimental protocols or flow kinematics. These models enable rapid discovery of accurate constitutive equations from limited data and can describe more complex flows. The flexibility of this framework enables its application to a wide range of material systems and engineering problems.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Mechanics
Zhongqiang Xiong, Wei Yu
Summary: An orientation-stretch-coupled constitutive equation is proposed for symmetric Cayley tree-like dendrimers, which self-consistently describes the linear relaxation spectrum and nonlinear viscoelastic behavior. The molecular stress is determined by the orientation-stretch-coupled conformation tensors of all segments. The predictions on both linear and nonlinear rheological behaviors are consistent with experiments, validating the rationality in treating coupling problems.
JOURNAL OF RHEOLOGY
(2022)
Article
Construction & Building Technology
Meng Wang, Zhijing Zhu, Rentai Liu, Shucai Li, Chunyu Zhang, Yankai Liu, Lianzhen Zhang, Jiwen Bai
Summary: This study investigated the rheology of Portland cement under different water-cement ratios and temperatures, revealing that the flow pattern and rheological model of cement slurry in high ground temperature environments are controlled by the water-cement ratio. The research results provide necessary guidance for the establishment of grouting diffusion theory and numerical model in high ground temperature environment.
CONSTRUCTION AND BUILDING MATERIALS
(2021)
Article
Mechanics
Zhongqiang Xiong, Wei Yu
Summary: A new semi-empirical constitutive equation is proposed to describe the intrinsic medium amplitude oscillatory shear (MAOS) behaviors and transient behaviors in start-up elongational experiments of comb polymers. The model discusses the molecular stress and hierarchical relaxation based on the orientation-stretch coupled conformation tensor of both backbone and arm, and utilizes a discrete spectrum for the backbone relaxation. The analytical solution of the equation set under MAOS and numerical solution under start-up extensional flows show good consistency with experimental results for nonlinear rheological behaviors.
JOURNAL OF RHEOLOGY
(2021)
Article
Mechanics
J. Esteban Lopez-Aguilar, Hamid R. Tamaddon-Jahromi, Octavio Manero
Summary: This study focuses on the computational modeling of shear-banded wormlike micellar solutions in complex planar Couette flow. The model used is the BMP+_t(p) model, which reproduces conventional WLM features such as shear thinning, viscoelasticity, and shear banding. The flow structure is analyzed through velocity, stress, and fluidity, comparing banded and non-banded responses. The study finds that shear-banding fluids display less intense viscosity/stress features and exhibit different flow behaviors in the presence of constrictions.
Article
Nutrition & Dietetics
Du Ho Kwon, Young Gyu Cho, Hyun Ah Park, Ho Seok Koo
Summary: Physical activity and muscle strengthening are crucial for preventing and managing metabolic syndrome. This study found that meeting guidelines for aerobic physical activity and muscle strengthening exercise was associated with a lower prevalence of metabolic syndrome. Additionally, individuals who engaged in both aerobic physical activity and muscle strengthening exercise had the lowest prevalence of metabolic syndrome.
Article
Medicine, General & Internal
Yong Whi Jeong, Jun Hyuk Koo, Ji Hye Huh, Young-Jin Kim, Hoyeon Jeong, Eun Young Kim, Dae Ryong Kang
Summary: This study proposes a new equation for estimating low-density lipoprotein cholesterol in South Koreans, which showed significantly improved performance compared to existing estimation equations. It reduces the underestimation rate and provides more accurate measurements for low-density lipoprotein cholesterol levels.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Mechanics
Andre Pincot, F. John Burpo, Elahe Javadi, Safa Jamali, Sean Farrington, Matthew J. Armstrong
Summary: A distinctive stress hysteresis phenomenon is observed in human blood rheology, which is related to the longer characteristic time of shear-induced rouleaux breakdown. The hysteresis data is used to fit parameters of the t-ESSTV model, which can predict various blood flow characteristics under different conditions. The correlation between fitting parameters and physiological data helps interpret the model behavior in physical terms.
Article
Endocrinology & Metabolism
Mehmet Kanbay, Sidar Copur, Dimitrie Siriopol, Abdullah Burak Yildiz, Abduzhappar Gaipov, Daniel H. Van Raalte, Katherine R. Tuttle
Summary: This study demonstrates that tirzepatide significantly reduces blood pressure and lipid levels, including total cholesterol, LDL cholesterol, and triglycerides, while increasing HDL cholesterol levels.
DIABETES OBESITY & METABOLISM
(2023)
Article
Polymer Science
Shijie Zhu, Xinsheng Xue, Jian Zhang, Shilun Zhang, Zhezhi Liu
Summary: Polymer flooding is a significant method for enhancing oil recovery globally. With optimized polymer synthesis, polymer solutions have improved performance and can adapt to complex oil and gas reservoirs. However, the improved properties of polymer solutions, such as enhanced elasticity and changed rheological behavior, pose challenges for the simulation of polymer flooding in reservoirs. Therefore, it is crucial to develop accurate modeling and precise limitation conditions for polymer flooding. Study results indicate that the rheological behavior of polymers can be described using the Carreau model, and the structural viscosity of hydrophobically associating polymer solutions greatly affects the elasticity and elastic modulus of the solution. Considering the influence of elastic characteristics on the rheological behavior, the relaxation time spectrum derived from small vibration experimental data is used to limit the characteristic relaxation time. By fully considering the relationship between different test parameters, the rheological constitutive equation of viscoelastic fluid can be optimized and improved.
Article
Clinical Neurology
Zhirong Yang, Duncan Edwards, Stephen Burgess, Carol Brayne, Jonathan Mant
Summary: This study investigated the potential associations between blood LDL-C, HDL-C, and triglycerides and post-stroke dementia. The results showed that higher LDL-C levels were associated with an increased risk of dementia, while lower triglyceride levels were associated with a decreased risk. There was no association between HDL-C levels and dementia.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Endocrinology & Metabolism
Amanda J. Berberich, Robert A. Hegele
Summary: We have been using DNA sequencing in our lipid clinic for more than 20 years. Dyslipidemia is usually determined biochemically. For moderate deviations in the lipid profile, the etiology is often a combination of a polygenic susceptibility component and secondary non-genetic factors. Severe dyslipidemia is more likely to have a monogenic etiology, although a specific single-gene cause is often not found. A severe phenotype can also result from a strong polygenic predisposition aggravated by secondary factors. An early age of onset, a family history of dyslipidemia or atherosclerotic cardiovascular disease may suggest a monogenic etiology. Clinical examination focuses on detecting manifestations of monogenic syndromic conditions for severe dyslipidemia. Secondary causes must be ruled out for all patients with dyslipidemia. Here we describe an experience-based practical approach to genetic testing of patients with severe deviations in low-density lipoprotein, triglycerides, high-density lipoprotein, as well as combined hyperlipidemia and dysbetalipoproteinemia.
BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Medical Laboratory Technology
Eduardo Martinez-Morillo, Maria Garcia-Garcia, Maria Angeles Luengo Concha, Luis Rello Varas
Summary: This study evaluated the Sampson equation for calculating LDL in comparison to the Friedewald and Martin-Hopkins equations, as well as a direct LDL method. Results showed that the Sampson equation provided similar LDL results to the Friedewald equation at certain triglyceride levels, but showed biases when compared to the Martin-Hopkins equation and the direct assay at different triglyceride levels. The study concluded that the Sampson equation may be a cost-efficient alternative for calculating LDL in clinical laboratories.
Article
Hematology
Lilli Arndt, Ileana Hernandez-Resendiz, Doreen Moos, Janine Dokas, Silvana Mueller, Franziska Jeromin, Richard Wagner, Uta Ceglarek, Iris M. Heid, Marcus Hoering, Gerhard Liebisch, Sonja C. Stadler, Ralph Burkhardt
Summary: This study demonstrates that deficiency of Trib1 promotes the formation of atherosclerotic lesions and increases plasma cholesterol and triglyceride levels in Ldlr(-/-) mice. It also suggests that Trib1 deficiency alters hepatic lipid metabolism and induces inflammation.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Multidisciplinary Sciences
B. Pialot, J. Gachelin, J. Provost, O. Couture
Summary: New processing techniques for manipulating blood at a microfluidic scale are being implemented, with a focus on in-line evaluation and monitoring of blood properties during extracorporeal circulation being a challenging task. This study demonstrates a non-invasive method for measuring blood hematocrit in a sub-millimeter medical tube using the non-Newtonian behavior of blood velocity profile, with promising results on human blood. The simplicity and effectiveness of this approach suggest its potential impact on in-vitro blood processing.
SCIENTIFIC REPORTS
(2021)
Article
Polymer Science
Ricardo Perez-Chavez, Jons Sanchez-Aguilar, Fausto Calderas, Lorenza Maddalena, Federico Carosio, Guadalupe Sanchez-Olivares
Summary: This study investigates the effects of compounding variables on flame retardant polymer composites using a statistical approach. By replacing aluminum trihydroxide with keratin fibers, the content is reduced while producing biocomposites with both flame retardancy and mechanical strength.
POLYMER DEGRADATION AND STABILITY
(2022)
Article
Mechanics
Luis Medina-Torres, Fausto Calderas, Luis Antonio Ramirez-Torres, Diola-Marina Nunez-Ramirez, Andres Navarrete Castro, Ma Josefa Bernad-Bernad, Octavio Manero
Summary: This study evaluates the effect of total cholesterol on the rheological behavior of rat blood through in vitro experiments. The results show that there are strong interactions between total cholesterol levels and blood cells.
KOREA-AUSTRALIA RHEOLOGY JOURNAL
(2022)
Article
Engineering, Chemical
Luis Antonio Ramirez-Torres, Luis Medina-Torres, Fausto Calderas, Diola Marina Nunez-Ramirez, Octavio Manero
Summary: The study analyzed the rheological response and computational hydrodynamic behavior to enhance understanding of the bioleaching process in mineral pulps. The results showed that smaller particle size increased the rheological parameters, decreased process time, and indirectly increased bacteria concentration in the medium, leading to higher gel strength. It was also found that a Rushton (top)/Maxflo (bottom) configuration in a dual-impeller bioreactor achieved the best performance, resulting in approximately 9% power savings. Enhanced hydrodynamic conditions were observed at a stirring speed of 400 rpm based on analysis of apparent viscosity maps, velocity fields, and streamlines.
CHEMICAL ENGINEERING & TECHNOLOGY
(2023)
Article
Chemistry, Applied
J. L. Perez-Salas, M. R. Moreno-Jimenez, N. E. Rocha-Guzman, W. Rosas-Flores, R. F. Gonzalez-Laredo, L. Medina-Torres, J. A. Gallegos-Infante
Summary: Bigels are biphasic systems formed by hydrogels and organogels and have been studied for use in bioactives delivery in food, pharmaceutical and cosmetic applications. The mechanical and microstructural properties of bigels can be influenced by the proportion of castor oil organogel, the concentration of organogelator, and the storage time. Increasing the proportion of organogel improves the mechanical response of bigels, while the use of castor oil results in higher values for centrifugal stability and rheological properties compared to other organogels.
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
(2023)
Article
Pharmacology & Pharmacy
Ramon Andres Pineda-Alvarez, Carolina Flores-Avila, Luis Medina-Torres, Jesus Gracia-Mora, Jose Juan Escobar-Chavez, Gerardo Leyva-Gomez, Mohammad-Ali Shahbazi, Maria Josefa Bernad-Bernad
Summary: This study evaluates the performance of Laponite in lecithin/gelatin composites and maltodextrin/sodium ascorbate mixtures. Nanoparticles were prepared using the gelatin desolvation method and turned into films via the solvent-casting method. The optimal composites were developed with 8.8 mg of Laponite, reducing particle size and avoiding agglomeration. Drug release in LGL MAS was fitted to first-order and Korsmeyer-Peppas models.
Article
Materials Science, Multidisciplinary
Perla Garcia-Guzman, Luis Medina-Torres, Ma. Josefa Bernad-Bernad, Fausto Calderas, Octavio Manero
Summary: In recent years, there has been a growing interest in dietary and pharmacological agents that inhibit cholesterol intestinal absorption. These compounds have various mechanisms to inhibit cholesterol absorption, such as affecting cholesterol solubilization, interfering with cholesterol diffusion, and inhibiting molecular mechanisms responsible for cholesterol absorption. This study investigated the characterization of different clays and their cholesterol adsorption capacity. The results showed that MMT Nanoclay has the highest cation exchange capacity and lowest Z potential, while MMT K10 and K30 have the highest cholesterol adsorption due to their high surface area. Isothermal studies also suggested that MMT allows for multilayer adsorption of cholesterol through hydrophobic sites.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Food Science & Technology
Migdalia S. Navidad-Murrieta, Hector A. Lopez-Munoz, Luis Medina Torres, Inocencio Higuera-Ciapara, Milton Vazquez-Lepe, Jose L. Garcia-Rivas, Beatriz Garcia-Gaitan, Sonia G. Sayago-Ayerdi, Gabriel Luna-Barcenas
Summary: This study encapsulated eight Hibiscus sabdariffa extracts with different concentrations, solvents, and decoction processes using spray-drying. Maltodextrin and gum arabic were used as carrying agents in aqueous and ethanolic media. Phenolic compounds were released under pH-controlled media. The study found strong molecular interactions between the carrying agents and phenolic compounds, indicating the potential for developing nutraceutical products.
ACS FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Abraham Osiris Martinez-Olivo, Victor Manuel Zamora-Gasga, Luis Medina-Torres, Alejandro Perez-Larios, Sonia Guadalupe Sayago-Ayerdi, Jorge Alberto Sanchez-Burgos
Summary: The health benefits provided by plant matrices are attributed to certain compounds that have been shown to have biological activity in vitro and in vivo. These compounds, which have been identified and studied, can be enhanced through structural chemical modifications or incorporation into polymer matrices. This review discusses the extraction of bioactive compounds from plant sources, their functionalization through double emulsions and nanoemulsions, toxicity, and pharmacokinetic aspects of encapsulation systems.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2023)
Article
Engineering, Chemical
L. Medina-Torres, I. H. Gonzalez Guillen, D. M. Nunez-Ramirez, P. Garcia-Guzman, F. Calderas, R. F. Gonzalez Laredo, M. A. Gonzalez Lozano, L. A. Ramirez Torres, O. Manero
Summary: This study analyzed the effect of the ultrafiltration (UF) process on the mechanical and rheological properties of Aloe vera mucilage. The results showed that when the mucilage was supplied as a diluted shear-thinning fluid, the UF efficiency was better. The findings provide an interesting and promising application for estimating the properties of Aloe vera using more realistic rheological models.
JOURNAL OF FOOD PROCESS ENGINEERING
(2023)
Review
Pharmacology & Pharmacy
Juan Luis Perez-Salas, Martha Rocio Moreno-Jimenez, Nuria Elizabeth Rocha-Guzman, Ruben Francisco Gonzalez-Laredo, Luis Medina-Torres, Jose Alberto Gallegos-Infante
Summary: This report provides an updated review of non-animal study models for screening anti-inflammatory drugs, including description of basic methods and three in vitro assay methods for enzymes relevant to skin inflammation. It also describes the development of cell culture models, including two-dimensional and three-dimensional models, as well as vascularized 3D skin models. Additionally, ex vivo skin models that better represent human skin in terms of structure, cell signaling mechanisms, and absorption effects are presented.
SCIENTIA PHARMACEUTICA
(2023)
Article
Chemistry, Applied
Abraham Osiris Martinez-Olivo, Victor Manuel Zamora-Gasga, Luis Medina-Torres, Alejandro Perez-Larios, Jorge Alberto Sanchez-Burgos
Summary: A double emulsion was developed to encapsulate and release mango seed extract, which showed diffusion-controlled release and zero-order kinetics. However, the double emulsion had limited inhibitory activity against Staphylococcus aureus and Saccharomyces cerevisiae.
FOOD HYDROCOLLOIDS FOR HEALTH
(2023)
