TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis

HIF2 α Is an Essential Molecular Brake for Postprandial Hepatic Glucagon Response Independent of Insulin Signaling

(2016) Sadeesh K. Ramakrishnan et al.   Cell Metabolism

SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.

(2015) Joseph P. Tiano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Artificial Biomelanin: Highly Light-Absorbing Nano-Sized Eumelanin by Biomimetic Synthesis in Chicken Egg White

(2014) Nicola Fyodor della Vecchia et al.   BIOMACROMOLECULES

Control of Gluconeogenesis by Metformin: Does Redox Trump Energy Charge?

(2014) Joseph A. Baur et al.   Cell Metabolism

AMPK and FoxO1 regulate catalase expression in hypoxic pulmonary arterial smooth muscle

(2013) Hanan Awad et al.   PEDIATRIC PULMONOLOGY

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: Implications for obesity

(2012) Hayley M. O’Neill et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

An Akt-independent pathway for regulation of gluconeogenesis

(2012) Joana Osório   Nature Reviews Endocrinology

Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling

(2011) Hariom Yadav et al.   Cell Metabolism

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

(2011) Russell A. Miller et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatitis C Virus Infection Promotes Hepatic Gluconeogenesis through an NS5A-Mediated, FoxO1-Dependent Pathway

(2011) L. Deng et al.   JOURNAL OF VIROLOGY

Metformin reduces intracellular reactive oxygen species levels by upregulating expression of the antioxidant thioredoxin via the AMPK-FOXO3 pathway

(2010) Xinguo Hou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK-dependent Repression of Hepatic Gluconeogenesis via Disruption of CREB·CRTC2 Complex by Orphan Nuclear Receptor Small Heterodimer Partner

(2010) Ji-Min Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase and FoxO Transcription Factors in Dietary Restriction-induced Longevity

(2009) Eric L. Greer et al.   Annals of the New York Academy of Sciences

Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach

(2009) J. R.B. Perry et al.   DIABETES

Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function

(2009) Huei-Min Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice

(2008) A. G. Gomez-Valades et al.   DIABETES