Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines

Ene‐Reductase: A Multifaceted Biocatalyst in Organic Synthesis

(2022) Debabrata Maiti et al.   CHEMISTRY-A EUROPEAN JOURNAL

Unlocking New Reactivities in Enzymes by Iminium Catalysis

(2022) Guangcai Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic Carbene Transfer Using Diazirines

(2022) Nicholas J. Porter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir

(2022) Ashleigh J. Burke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Proton Transfer Catalysis by Stereocomplementary Old Yellow Enzymes for C═C Bond Isomerization Reaction

(2022) Marina S. Robescu et al.   ACS Catalysis

Enzymatic Nitrogen Insertion into Unactivated C–H Bonds

(2022) Soumitra V. Athavale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ground-State Electron Transfer as an Initiation Mechanism for Biocatalytic C–C Bond Forming Reactions

(2021) Haigen Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unlocking the Stereoselectivity and Substrate Acceptance of Enzymes: Proline‐Induced Loop Engineering Test

(2021) Ge Qu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Creation of an Engineered Amide Synthetase Biocatalyst by the Rational Separation of a Two‐Step Nitrile Synthetase

(2021) Alexis J. A. Hennessy et al.   CHEMBIOCHEM

Biocatalysis making waves in organic chemistry

(2021) Ulf Hanefeld et al.   CHEMICAL SOCIETY REVIEWS

Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction

(2021) Rebecca Crawshaw et al.   Nature Chemistry

Conventional and microwave prompted synthesis of aryl(alkyl)azole oximes, 1H-NMR spectroscopic determination of E/Z isomer ratio and HOMO-LUMO analysis

(2021) Irem Bozbey et al.   JOURNAL OF MOLECULAR STRUCTURE

Selective Enzymatic Oxidation of Silanes to Silanols

(2020) Susanne Bähr et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic reductions ‐ A Chemist's perspective

(2020) Frank Hollmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoenzymatic Hydrogenation of Heteroaromatic Olefins using ‘Ene’‐Reductases with Photoredox Catalysts

(2020) Todd Hyster et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Biocatalysis: Using Non-Natural Single Electron Transfer Mechanisms to Access New Enzymatic Functions

(2019) Todd K. Hyster   SYNLETT

Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases

(2018) Kathrin Heckenbichler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biocatalytic reduction of activated C C-bonds and beyond: emerging trends

(2018) Christoph K Winkler et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Discovery, Characterization, Engineering, and Applications of Ene-Reductases for Industrial Biocatalysis

(2018) Helen S. Toogood et al.   ACS Catalysis

Investigating Saccharomyces cerevisiae alkene reductase OYE 3 by substrate profiling, X-ray crystallography and computational methods

(2018) Robert W. Powell et al.   Catalysis Science & Technology

Origin of Remarkably Different Acidity of Hydroxycoumarins—Joint Experimental and Theoretical Studies

(2017) Paweł Mateusz Nowak et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase

(2017) Tobias Werther et al.   Nature Communications

Old Yellow Enzyme-Catalysed Asymmetric Hydrogenation: Linking Family Roots with Improved Catalysis

(2017) Anika Scholtissek et al.   Catalysts

Synthesis of pyrazine via chemoselective reduction of β-keto-α-oximino ester using baker’s yeast

(2016) Kilwoong Mo et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Reduction of α,β-Unsaturated Ketones by Old Yellow Enzymes: Mechanistic Insights from Quantum Mechanics/Molecular Mechanics Calculations

(2015) Richard Lonsdale et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An evolutionary biochemist's perspective on promiscuity

(2015) Shelley D. Copley   TRENDS IN BIOCHEMICAL SCIENCES

Structural and Functional Consequences of Circular Permutation on the Active Site of Old Yellow Enzyme

(2015) Ashley B. Daugherty et al.   ACS Catalysis

New developments in ‘ene’-reductase catalysed biological hydrogenations

(2014) Helen S Toogood et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Brønsted Acid Catalyzed Benzylic C–H Bond Functionalization of Azaarenes: Nucleophilic Addition to Nitroso Compounds

(2014) Xu Gao et al.   ORGANIC LETTERS

Unusual reactions mediated by FMN-dependent ene- and nitro-reductases

(2013) Katharina Durchschein et al.   GREEN CHEMISTRY

A One-Pot Preparation of 5-Oxo 2,4-Disubstituted 2,5-Dihydro-1H-imidazol-2-carboxylates from α-Bromo Esters

(2011) Dariusz Cież et al.   SYNLETT

The flavoprotein-catalyzed reduction of aliphatic nitro-compounds represents a biocatalytic equivalent to the Nef-reaction

(2010) Katharina Durchschein et al.   GREEN CHEMISTRY

Determinants of Substrate Binding and Protonation in the Flavoenzyme Xenobiotic Reductase A

(2010) Olivia Spiegelhauer et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinetic Characterization of Xenobiotic Reductase A fromPseudomonas putida86

(2009) Olivia Spiegelhauer et al.   BIOCHEMISTRY

Structural Basis of Substrate Specificity of Plant 12-Oxophytodienoate Reductases

(2009) Constanze Breithaupt et al.   JOURNAL OF MOLECULAR BIOLOGY

HOLLOW: Generating Accurate Representations of Channel and Interior Surfaces in Molecular Structures

(2008) Bosco K Ho et al.   BMC STRUCTURAL BIOLOGY

Reduction of aliphatic nitro groups using an obligately anaerobic whole cell biocatalyst

(2007) Hassan Korbekandi et al.   ENZYME AND MICROBIAL TECHNOLOGY