期刊
TETRAHEDRON LETTERS
卷 53, 期 24, 页码 3086-3090出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.04.037
关键词
Bis-Betti base; Condensation; Multi-component reaction; Aldehydes; 3-Amino-5-methylisoxazole; Dihydroxynaphthalene
资金
- Center of Excellence of Chemistry
- Research Council of the University of Isfahan
A novel, diastereoselective, one-pot synthesis of new bis-Betti bases via condensation of dihydroxynaphthalene, two equivalents of aryl aldehydes, and two equivalents of 3-amino-5-methylisoxazole is reported. Conversion into the adducts was almost quantitative without the use of solvent or catalyst. The reaction conditions are very simple and enable easy isolation of the product. (C) 2012 Elsevier Ltd. All rights reserved.
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