Topical metformin 30 % gel in the treatment of acne vulgaris: A split face, placebo controlled study

作者

Nermeen Bedair¹ , Rehab Shamma² , Nesma Abdo³ , Mohammed Elkomy⁴

1. Department of dermatology, Faculty of medicine, Helwan Univesity
2. Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University
3. National Hepatology and Tropical Medicine Institute, Cairo, Egypt
4. Department of Dermatology, Faculty of Medicine, Cairo University

会议/活动

American Academy of Dermatology Meeting 2023, March 2023 (New orleans, United States)

海报摘要

This split face study was designed to evaluate the efficacy and safety of 12 weeks application of daily topical metformin in comparison to placebo in the treatment of 21 adolescent female patients suffering from acne vulgaris. Papules were the first lesions to start showing significant improvement by week 4, while comedones took 12 weeks to show significant improvement. Conclusion:Topical metformin nanoemulsion gel can be a promising safe and effective treatment of acne vulgaris.

关键词

Acne, Metformin, Topical

研究领域

Medicine

参考文献

1. Chernyshov P v., Zouboulis CC, Tomas-Aragones L, Jemec GB, Manolache L, Tzellos T, et al. Quality of life measurement in acne. Position Paper of the European Academy of Dermatology and Venereology Task Forces on Quality of Life and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa. Vol. 32, Journal of the European Academy of Dermatology and Venereology. Blackwell Publishing Ltd; 2018. p. 194–208.

基金

1. None

补充材料

暂无数据

附加信息

利益冲突

No competing interests were disclosed.

数据可用性声明

The datasets generated during and / or analyzed during the current study are available from the corresponding author on reasonable request.

知识共享许可协议

Copyright © 2023 Bedair et al. This is an open access work distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.