Čedomir Stevčić

Serbia n/a

论文

评论了 Novel mechanism of hypoxic neuronal injury mediated by non‐excitatory amino acids and astroglial swelling
The authors found that a set of amino acids, which normally maintain brain function, play a crucial role in the brain deterioration that could occur after a stroke or traumatic brain injury. For the first time, there is astonishing evidence that four common nonexcitatory amino acids cause permanent and destructive swelling of both the astrocytes and the neurons.

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评论了 If you don’t let it in, you don’t have to get it out: Thought preemption as a method to control unwanted thoughts
By analyzing how 80 English-speaking adults came up with new associations to common words, the authors discovered that proactively avoiding an association in the first place can be a much more efficient means of avoiding an unwanted thought and that can also help prevent the repetitive looping of unwanted thoughts.

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评论了 Amyloid‐beta misfolding and GFAP predict risk of clinical Alzheimer's disease diagnosis within 17 years
The results obtained here with the immuno-infrared sensor are backed by a comparative study that was conducted using complementary single-molecule array (SIMOA) technology, and the authors analyzed blood plasma from 68 participants (aged between 50 and 75) for potential Alzheimer’s biomarkers during the 17-year follow-up to 240 control subjects who had not received such a diagnosis. This approach could lead to a non-invasive and cost-effective multifactorial diagnostic tool for prescreening older adults regarding the risk of developing Alzheimer’s disease.

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评论了 Second law of information dynamics
The authors discovered a potential way to predict genetic mutations before they occur by using a new physics law (i.e. the second law of information dynamics, or “infodynamics,”), which behaves differently from the second law of thermodynamics, and the results can also be applied for computing, big data, evolutionary biology, physics, and cosmology develop in the future.

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评论了 Gastric antiulcer, antisecretory and cytoprotective properties of celery (Apium graveolens) in rats
The authors examined the impact of celery extract on the treatment of stomach ulcers and the overall protective benefits on the gastrointestinal system of rats and they discovered that celery extract consumption before the developed stomach ulcers caused much less gastric damage, most likely due to the antioxidant properties of celery.

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评论了 Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens) in Rats
The authors discovered that consuming celery extract for 60 days caused a significant decrease in the blood lipids of rats, including triglycerides, total cholesterol, and LDL “bad” cholesterol - common heart disease biomarkers can improve by eating celery.

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评论了 PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE
The authors found that the loss of the protein pigment epithelium-derived factor (PEDF), which protects retinal support cells, is a driver of aging-related changes in the retina such as age-related macular degeneration (AMD).

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评论了 Multimodal perception links cellular state to decision-making in single cells
The authors extended the concept of contextual, multimodal perception found in humans to individual cells as they discovered that single cells make decisions much more autonomously than previously thought.

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评论了 High‐dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression
The study on the effects of high dosages of Vitamin B6 on young adults (over 300 participants) showed that high-dose Vitamin B6 supplements can decrease depression and anxiety by altering brain activity levels for the prevention or treatment of mood disorders

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评论了 Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers
The authors investigated the link between belly fat and the risk of metabolic illness - how epigenetic marks in fat tissue (from 538 TwinsUK participants) change as belly fat builds up. They discovered nine genes that are highly relevant to the risk of metabolic disease among which was a gene with detected epigenetic alterations that were identified as a possible method by which diet might impact belly fat accumulation.

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评论了 Hypocotyls of Lepidium meyenii (maca), a plant of the Peruvian highlands, prevent ultraviolet A-, B-, and C-induced skin damage in rats
The authors discovered that maca contains compounds that may prevent ultraviolet damage to the skin because the rats who had maca extract topically applied to their skin received protection from UV rays, compared to the commercial sunscreen control group.

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评论了 A recipe for success? Sustaining creativity among first-time creative producers.
The study showed one factor that may explain why some first-time creators find it difficult to repeat their initial creative productions while others continue to produce creative works – the authors found that rewarding first-time creators of novel ideas with awards or other forms of recognition can significantly decrease their likelihood to produce future creative work.

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评论了 Remodeling of the m6A RNA landscape in the conversion of acute lymphoblastic leukemia cells to macrophages
The authors explain how changing the chemical modifications (i.e. epigenetics) of a specific type of leukemia cell’s genetic material (i.e. the messenger RNA) causes the transformation of highly proliferative leukemia cells into normal cells that no longer multiply.

论文

评论了 Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine
The authors found a new signaling molecule, a key molecule named inosine, that forces brown fat cells to consume more energy so they believe that this finding could one day be used as a treatment for obesity.

论文

评论了 Fab-compatible Processed Transparent Organic Photodiodes for High-Detectivity CMOS Image Sensors
The authors fabricated green absorbing transparent organic photodetectors that are highly sensitive and compatible with CMOS fabrication methods by combining one of these green organic photodetectors with a silicon photodiode with red and blue filters, and this new green-light absorbing photodetectors could be useful for light-based heart-rate monitoring, fingerprint recognition, and devices that detect the presence of nearby objects.