Čedomir Stevčić

Serbia n/a

论文

评论了 Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: results of a meta-analysis
This meta-analysis of 15 placebo-controlled studies concluded that “neither soy foods nor isoflavone supplements alter the measures of bioavailable testosterone concentrations in men.” Many other studies have shown that soy consumption does not affect estrogen and testosterone levels.

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评论了 Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway
The authors discussed how glyceollins, which are produced by certain leguminous plants as defense molecules in response to stress, may trigger antioxidant activity that can have neuroprotective effects against glutamate-induced damage and attenuated scopolamine-induced memory deficits.

论文

评论了 Origin and function of activated fibroblast states during zebrafish heart regeneration
The authors simulated myocardial infarction injuries in the hearts of their zebrafish and found that zebrafish may repair heart tissue after an injury as connective tissue cells play a significant role in heart regeneration by temporarily entering an activated state.

论文

评论了 Soy isoflavones prevent bone resorption and loss, a systematic review and meta-analysis of randomized controlled trials
This meta-analysis analyzed 52 research trials to understand if there was an association between soy isoflavone consumption and bone mineral density, and it concluded that soy isoflavones could help prevent osteoporosis in people of all weights.

讨论圈

评论了 Medical Advancements
Researchers from Norway and Denmark discovered that loperamide, which is a commonly used medication for diarrhea, is a potential treatment medication for the core symptoms of autism spectrum disorder (ASD), and their study is the first to use protein interaction networks to study whether existing drugs could treat autism: 🔗https://doi.org/10.3389/fphar.2022.995439🔗

论文

评论了 A Synthetic Hydrogel Composite with a Strength and Wear Resistance Greater than Cartilage
The authors created a gel-based cartilage replacement (composed of water-absorbing polymers) for sore knees that is stronger and more durable than the real cartilage, and they hope to conduct clinical trials next year.

论文

评论了 Glyceollin-Elicited Soy Protein Consumption Induces Distinct Transcriptional Effects As Compared to Standard Soy Protein
The study shows that glyceollins, which are produced by certain leguminous plants as defense molecules in response to stress, have distinct bioactive properties that may lower LDL “bad” cholesterol and high triglyceride levels.

论文

评论了 Habitual consumption of soy protein and isoflavones and risk of metabolic syndrome in adults ≥ 40 years old: a prospective analysis of the Korean Multi-Rural Communities Cohort Study (MRCohort)
By analyzing the connection between regular consumption of soy protein/isoflavones with metabolic syndrome risk among 5,500 Korean men and women over 40 (no metabolic syndrome at the start), the authors discovered that regular consumption of soy foods is protective against metabolic syndrome (i.e. a cluster of chronic conditions that commonly occur together such as high blood sugar and high blood pressure).

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评论了 Genistein as Potential Therapeutic Candidate for Menopausal Symptoms and Other Related Diseases
The results from this study show how isoflavone genistein from soy could have therapeutic effects on menopause symptoms like hot flashes (sudden feeling of warmth in the upper body such as the face, neck, and chest) and many other menopause-related diseases, and there are few or no adverse side effects.

论文

评论了 Soy intake and vasomotor menopausal symptoms among midlife women: a pooled analysis of five studies from the InterLACE consortium
The authors discovered a lower incidence of hot flashes, which are a common complaint among women during menopause, among menopausal women who consumed soy foods (but not soy milk) compared to those who did not.

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评论了 Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
The authors discovered why some smokers, against the odds, manage to avoid lung cancer (i.e. only 10-20% of lifelong smokers will develop lung cancer) - some smokers may have a robust mechanism or resilience that helps to limit mutations in the lungs that protect them from lung cancer (i.e. the results show significantly more mutations in the lung cells of smokers as opposed to non-smokers). Moreover, the number of cell mutations was closely associated with the amount the person had smoked but once the person had smoked 23 “pack years” (i.e. one pack of cigarettes smoked per day for one year) the increase in cell mutations stopped.

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评论了 Agriculture and climate change are reshaping insect biodiversity worldwide
There are alarming links between insect population decline and higher temperatures as authors discovered that the more the average temperature in a region has increased the greater the ecological damage, and the more evidence of insect population collapse (reductions of almost 50% in the abundance and 27% in the number of species within insect assemblages).

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评论了 Crop production in the USA is frequently limited by a lack of pollinators
The authors examined seven crops grown in 13 states across America (at 131 locations) and found that five of them (such as apples, blueberries, and cherries) generated decreased yields due to a lack of native bees. Therefore, they estimated that over $1.5 billion is the nationwide annual production value of wild pollinators just for these seven crops, so this value for all pollinator-dependent crops would be much greater.

论文

评论了 Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders
Appropriate and safe daily lycopene intake can vary from 2 to 20 mg for most healthy people, which is easily obtained through the diet, but people with cancer or cardiovascular disease can benefit from higher doses (i.e. 35-75 mg/day range).

论文

评论了 Lycopene presence in facial skin corneocytes and sebum and its association with circulating lycopene isomer profile: Effects of age and dietary supplementation
The authors discovered that young people have more lycopene in their skin cells than older people and that supplementation increased the concentrations in both groups.