4.7 Article

Synthesis and characterization of small circular double-stranded RNAs

Journal

CHEMICAL COMMUNICATIONS
Volume 47, Issue 7, Pages 2125-2127

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc04551a

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Small circular double-stranded RNAs (dsRNAs) were synthesized. The structural analysis by atomic force microscopy gave direct images for the interpretation of the structural strain present in circular dsRNAs. Finally, we demonstrated that circular dsRNA caused RNAi effect in cells.

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