Adaptive designs for clinical trials assessing biomarker-guided treatment strategies

A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study

(2013) C.A. Drukker et al.   INTERNATIONAL JOURNAL OF CANCER

Comparison of PAM50 Risk of Recurrence Score With Oncotype DX and IHC4 for Predicting Risk of Distant Recurrence After Endocrine Therapy

(2013) Mitch Dowsett et al.   JOURNAL OF CLINICAL ONCOLOGY

Selecting Breast Cancer Patients for Chemotherapy: The Opening of the UK OPTIMA Trial

(2012) J. Bartlett et al.   CLINICAL ONCOLOGY

A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

(2011) Martin Filipits et al.   CLINICAL CANCER RESEARCH

Prognostic Value of a Combined Estrogen Receptor, Progesterone Receptor, Ki-67, and Human Epidermal Growth Factor Receptor 2 Immunohistochemical Score and Comparison With the Genomic Health Recurrence Score in Early Breast Cancer

(2011) Jack Cuzick et al.   JOURNAL OF CLINICAL ONCOLOGY

Prediction of Risk of Distant Recurrence Using the 21-Gene Recurrence Score in Node-Negative and Node-Positive Postmenopausal Patients With Breast Cancer Treated With Anastrozole or Tamoxifen: A TransATAC Study

(2010) Mitch Dowsett et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Clinical Trials With Biomarkers: Design Issues

(2010) B. Freidlin et al.   JNCI-Journal of the National Cancer Institute

Clinical Trial Designs for Predictive Biomarker Validation: Theoretical Considerations and Practical Challenges

(2009) Sumithra J. Mandrekar et al.   JOURNAL OF CLINICAL ONCOLOGY

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial

(2009) Kathy S Albain et al.   LANCET ONCOLOGY

Clinical trial designs for evaluating the medical utility of prognostic and predictive biomarkers in oncology

(2009) Richard Simon   Personalized Medicine

A Mixed Approach for Proving Non-Inferiority in Clinical Trials with Binary Endpoints

(2008) Valentin Rousson et al.   BIOMETRICAL JOURNAL

Bayesian adaptive design for targeted therapy development in lung cancer — a step toward personalized medicine

(2008) Xian Zhou et al.   Clinical Trials