The Energy Metabolism Dysfunction in Psychiatric Disorders Postmortem Brains: Focus on Proteomic Evidence

Psychiatric disorders biochemical pathways unraveled by human brain proteomics

(2016) Verônica M. Saia-Cereda et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Differential proteome and phosphoproteome may impact cell signaling in the corpus callosum of schizophrenia patients

(2016) Verônica M. Saia-Cereda et al.   SCHIZOPHRENIA RESEARCH

Effect of MK-801 and Clozapine on the Proteome of Cultured Human Oligodendrocytes

(2016) Juliana S. Cassoli et al.   Frontiers in Cellular Neuroscience

Proteomic analysis of the postsynaptic density implicates synaptic function and energy pathways in bipolar disorder

(2016) M Föcking et al.   Translational Psychiatry

Brain membrane lipids in major depression and anxiety disorders

(2015) Christian P. Müller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Proteomics of the corpus callosum unravel pivotal players in the dysfunction of cell signaling, structure, and myelination in schizophrenia brains

(2015) Verônica M. Saia-Cereda et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Proteomic Enrichment Analysis of Psychotic and Affective Disorders Reveals Common Signatures in Presynaptic Glutamatergic Signaling and Energy Metabolism

(2015) Michael G. Gottschalk et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Glucose metabolism alterations in patients with bipolar disorder

(2015) Gianluca Rosso et al.   JOURNAL OF AFFECTIVE DISORDERS

Distinct proteomic profiles in post-mortem pituitary glands from bipolar disorder and major depressive disorder patients

(2015) Viktoria Stelzhammer et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Mitochondrial function in the brain links anxiety with social subordination

(2015) Fiona Hollis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteomic pathway analysis of the hippocampus in schizophrenia and bipolar affective disorder implicates 14-3-3 signaling, aryl hydrocarbon receptor signaling, and glucose metabolism: Potential roles in GABAergic interneuron pathology

(2015) Klaus Oliver Schubert et al.   SCHIZOPHRENIA RESEARCH

Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy

(2015) Hans-Gert Bernstein et al.   SCHIZOPHRENIA RESEARCH

MK-801 treatment affects glycolysis in oligodendrocytes more than in astrocytes and neuronal cells: insights for schizophrenia

(2015) Paul C. Guest et al.   Frontiers in Cellular Neuroscience

Mortality in Mental Disorders and Global Disease Burden Implications

(2015) Elizabeth Reisinger Walker et al.   JAMA Psychiatry

Schizophrenia

(2015) René S. Kahn et al.   Nature Reviews Disease Primers

Targeted Multiplexed Selected Reaction Monitoring Analysis Evaluates Protein Expression Changes of Molecular Risk Factors for Major Psychiatric Disorders

(2015) Hendrik Wesseling et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Clozapine promotes glycolysis and myelin lipid synthesis in cultured oligodendrocytes

(2015) Johann Steiner et al.   Frontiers in Cellular Neuroscience

Staging systems in bipolar disorder: an International Society for Bipolar Disorders Task Force Report

(2014) F. Kapczinski et al.   ACTA PSYCHIATRICA SCANDINAVICA

Glutamate Metabolism in Major Depressive Disorder

(2014) Chadi G. Abdallah et al.   AMERICAN JOURNAL OF PSYCHIATRY

2DE: The Phoenix of Proteomics

(2014) Bruno M. Oliveira et al.   Journal of Proteomics

Proteomic and genomic evidence implicates the postsynaptic density in schizophrenia

(2014) M Föcking et al.   MOLECULAR PSYCHIATRY

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

(2014) Rachel J Perry et al.   NATURE MEDICINE

Downregulation of Transketolase Activity Is Related to Inhibition of Hippocampal Progenitor Cell Proliferation Induced by Thiamine Deficiency

(2014) Yanling Zhao et al.   Biomed Research International

Metabolic Syndrome and Metabolic Abnormalities in Bipolar Disorder: A Meta-Analysis of Prevalence Rates and Moderators

(2013) Davy Vancampfort et al.   AMERICAN JOURNAL OF PSYCHIATRY

Excess Early Mortality in Schizophrenia

(2013) Thomas Munk Laursen et al.   Annual Review of Clinical Psychology

Structural Abnormalities in Bipolar Euthymia: A Multicontrast Molecular Diffusion Imaging Study

(2013) Erick Jorge Canales-Rodríguez et al.   BIOLOGICAL PSYCHIATRY

A pilot study of alterations in high energy phosphoryl compounds and intracellular pH in unmedicated adolescents with bipolar disorder

(2013) Wade A. Weber et al.   JOURNAL OF AFFECTIVE DISORDERS

Mitochondrial respiration in blood platelets of depressive patients

(2013) Jana Hroudová et al.   MITOCHONDRION

Bipolar Disorder and Metabolic Syndrome: A Systematic Review

(2013) Letícia Czepielewski et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function

(2012) Daniel Martins-de-Souza et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

The neuroprogressive nature of major depressive disorder: pathways to disease evolution and resistance and therapeutic implications

(2012) S Moylan et al.   MOLECULAR PSYCHIATRY

Impaired mitochondrial function in psychiatric disorders

(2012) Husseini Manji et al.   NATURE REVIEWS NEUROSCIENCE

Creatine metabolism and psychiatric disorders: Does creatine supplementation have therapeutic value?

(2012) Patricia J. Allen   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients

(2012) D Martins-de-Souza et al.   Translational Psychiatry

Brain Connectivity and Mental Illness

(2012) Alex Fornito et al.   Frontiers in Psychiatry

Activity of mitochondrial respiratory chain is increased by chronic administration of antidepressants.

(2011) Giselli Scaini et al.   ACTA NEUROPSYCHIATRICA

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

Common Proteomic Changes in the Hippocampus in Schizophrenia and Bipolar Disorder and Particular Evidence for Involvement of Cornu Ammonis Regions 2 and 3

(2011) Melanie Föcking et al.   ARCHIVES OF GENERAL PSYCHIATRY

Prevalence and Correlates of Bipolar Spectrum Disorder in the World Mental Health Survey Initiative

(2011) Kathleen R. Merikangas et al.   ARCHIVES OF GENERAL PSYCHIATRY

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Insulin dysfunction and allostatic load in bipolar disorder

(2011) Elisa Brietzke et al.   Expert Review of Neurotherapeutics

The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes

(2011) Lucia Lisi et al.   Journal of Neuroinflammation

Abnormalities in Mitochondrial Structure in Cells from Patients with Bipolar Disorder

(2010) Anne M. Cataldo et al.   AMERICAN JOURNAL OF PATHOLOGY

The Role of Energy Metabolism Dysfunction and Oxidative Stress in Schizophrenia Revealed by Proteomics

(2010) Daniel Martins-de-Souza et al.   ANTIOXIDANTS & REDOX SIGNALING

The Neuroproteomics of Schizophrenia

(2010) Jane A. English et al.   BIOLOGICAL PSYCHIATRY

Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia

(2010) Hayley B. Clay et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Phospholipid profile in the postmortem hippocampus of patients with schizophrenia and bipolar disorder: No changes in docosahexaenoic acid species

(2010) Kei Hamazaki et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia

(2010) Daniel Martins-de-Souza et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia

(2010) Daniel Martins-de-Souza et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Depressive behaviour in children diagnosed with a mitochondrial disorder

(2010) E. Morava et al.   MITOCHONDRION

Increased levels of circulating insulin-related peptides in first-onset, antipsychotic naïve schizophrenia patients

(2010) P C Guest et al.   MOLECULAR PSYCHIATRY

Rethinking schizophrenia

(2010) Thomas R. Insel   NATURE

In vitro findings of alterations in intracellular calcium homeostasis in schizophrenia

(2010) Lukasz Bojarski et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Beyond the serotonin hypothesis: Mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders

(2010) Ann Gardner et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Quantitative proteomics for investigating psychiatric disorders

(2010) Michaela D. Filiou et al.   Proteomics Clinical Applications

Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia

(2009) Jun-Feng Wang et al.   BIPOLAR DISORDERS

Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation

(2009) Daniel Martins-de-Souza et al.   BMC Psychiatry

Metabolic profile of antipsychotic-naive individuals with non-affective psychosis

(2009) Emilio Fernandez-Egea et al.   BRITISH JOURNAL OF PSYCHIATRY

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia

(2009) Daniel Martins-de-Souza et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Glial cells in schizophrenia: pathophysiological significance and possible consequences for therapy

(2009) Hans-Gert Bernstein et al.   Expert Review of Neurotherapeutics

The interplay between mitochondrial complex I, dopamine and Sp1 in schizophrenia

(2009) Dorit Ben-Shachar   JOURNAL OF NEURAL TRANSMISSION

Automated 2D Peptide Separation on a 1D Nano-LC-MS System

(2009) Paul Taylor et al.   JOURNAL OF PROTEOME RESEARCH

Brain lipid concentrations in bipolar disorder

(2009) Miki Igarashi et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Neuroproteomics: understanding the molecular organization and complexity of the brain

(2009) Alex Bayés et al.   NATURE REVIEWS NEUROSCIENCE

Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

(2009) Brandi Rollins et al.   PLoS One

2-D DIGE analysis implicates cytoskeletal abnormalities in psychiatric disease

(2009) Jane A. English et al.   PROTEOMICS

Energy-Efficient Action Potentials in Hippocampal Mossy Fibers

(2009) H. Alle et al.   SCIENCE

Mitochondrial involvement in psychiatric disorders

(2008) Ling Shao et al.   ANNALS OF MEDICINE

N-Acetyl Cysteine for Depressive Symptoms in Bipolar Disorder—A Double-Blind Randomized Placebo-Controlled Trial

(2008) Michael Berk et al.   BIOLOGICAL PSYCHIATRY

Major depression in adolescent children consecutively diagnosed with mitochondrial disorder

(2008) S. Koene et al.   JOURNAL OF AFFECTIVE DISORDERS

Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis

(2008) Daniel Martins-de-Souza et al.   JOURNAL OF NEURAL TRANSMISSION

Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia

(2008) Daniel Martins-de-Souza et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Proteomic analysis of membrane microdomain-associated proteins in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder reveals alterations in LAMP, STXBP1 and BASP1 protein expression

(2008) ÁT Behan et al.   MOLECULAR PSYCHIATRY

A glimmer of light for neuropsychiatric disorders

(2008) Steven E. Hyman   NATURE

Inhibition of mitochondrial respiratory chain in brain of rats subjected to an experimental model of depression

(2008) Gislaine T. Rezin et al.   NEUROCHEMISTRY INTERNATIONAL

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neuroanatomical Pattern of Mitochondrial Complex I Pathology Varies between Schizophrenia, Bipolar Disorder and Major Depression

(2008) Dorit Ben-Shachar et al.   PLoS One

Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia

(2008) Maurício Kunz et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Proteomic analysis reveals protein changes within layer 2 of the insular cortex in schizophrenia

(2008) Kyla Pennington et al.   PROTEOMICS

The pre-omics era: The early days of two-dimensional gels

(2008) Patrick H. O'Farrell   PROTEOMICS

Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder

(2008) Robert K. McNamara et al.   PSYCHIATRY RESEARCH

Glucose abnormalities in the siblings of people with schizophrenia

(2008) Emilio Fernandez-Egea et al.   SCHIZOPHRENIA RESEARCH

The prevalence of metabolic syndrome in patients with bipolar disorder

(2007) Maria P. Garcia-Portilla et al.   JOURNAL OF AFFECTIVE DISORDERS

Hepatic Insulin Resistance in Antipsychotic Naive Schizophrenic Patients: Stable Isotope Studies of Glucose Metabolism

(2007) Lonneke J. M. van Nimwegen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM