Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathy
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Toll-like receptor 4 stimulation with monophosphoryl lipid A ameliorates motor deficits and nigral neurodegeneration triggered by extraneuronal α-synucleinopathy
Authors
Keywords
α-synuclein, Toll-like receptor, Inclusion pathology, Neuroinflammation, Monophosphoryl lipid A
Journal
Molecular Neurodegeneration
Volume 12, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-07-04
DOI
10.1186/s13024-017-0195-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MCP-1-mediated activation of microglia promotes white matter lesions and cognitive deficits by chronic cerebral hypoperfusion in mice
- (2017) Bangqing Yuan et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Inflammatory pre-conditioning restricts the seeded induction of α-synuclein pathology in wild type mice
- (2017) Emily J. Koller et al. Molecular Neurodegeneration
- Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration
- (2016) Michel Goedert et al. BRAIN
- Microglia in Alzheimer's Disease: The Good, the Bad and the Ugly
- (2016) Dario Tejera et al. Current Alzheimer Research
- Gene silencing of MCP-1 prevents microglial activation and inflammatory injury after intracerebral hemorrhage
- (2016) Zhao Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Monophosphoryl Lipid-A: A Promising Tool for Alzheimer’s Disease Toll
- (2016) Ângela Rego et al. JOURNAL OF ALZHEIMERS DISEASE
- Glia and alpha-synuclein in neurodegeneration: A complex interaction
- (2016) Dominik Brück et al. NEUROBIOLOGY OF DISEASE
- Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril
- (2016) Changyoun Kim et al. Scientific Reports
- Studies of lipopolysaccharide effects on the induction of α-synuclein pathology by exogenous fibrils in transgenic mice
- (2015) Nicola J. Rutherford et al. Molecular Neurodegeneration
- Multiple-System Atrophy
- (2015) Alessandra Fanciulli et al. NEW ENGLAND JOURNAL OF MEDICINE
- Brain region-specific gene expression profiles in freshly isolated rat microglia
- (2015) Karlijn J. Doorn et al. Frontiers in Cellular Neuroscience
- MPLA inhibits release of cytotoxic mediators from human neutrophils while preserving efficient bacterial killing
- (2014) Marie- Hélène Ruchaud-Sparagano et al. IMMUNOLOGY AND CELL BIOLOGY
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Extracellular α-synuclein—a novel and crucial factor in Lewy body diseases
- (2014) He-Jin Lee et al. Nature Reviews Neurology
- Screening of Toll-Like Receptors Expression in Multiple System Atrophy Brains
- (2013) Tomasz Brudek et al. NEUROCHEMICAL RESEARCH
- Transmission of multiple system atrophy prions to transgenic mice
- (2013) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toll-like receptor 4 stimulation with the detoxified ligand monophosphoryl lipid A improves Alzheimer's disease-related pathology
- (2013) J.-P. Michaud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Immunobiology of Toll-Like Receptor 4 Agonists
- (2013) Julia K. Bohannon et al. SHOCK
- Systemic proteasome inhibition triggers neurodegeneration in a transgenic mouse model expressing human α-synuclein under oligodendrocyte promoter: implications for multiple system atrophy
- (2012) Nadia Stefanova et al. ACTA NEUROPATHOLOGICA
- Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
- (2012) Lisa Fellner et al. GLIA
- The Role of Glia in Alpha-Synucleinopathies
- (2012) Lisa Fellner et al. MOLECULAR NEUROBIOLOGY
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
- (2011) Lisa Fellner et al. ACTA NEUROPATHOLOGICA
- Toll-Like Receptor 4 Promotes α-Synuclein Clearance and Survival of Nigral Dopaminergic Neurons
- (2011) Nadia Stefanova et al. AMERICAN JOURNAL OF PATHOLOGY
- Glia: Initiators and progressors of pathology in Parkinson's disease
- (2011) Glenda M. Halliday et al. MOVEMENT DISORDERS
- Misfolded α-synuclein and toll-like receptors: therapeutic targets for Parkinson's disease
- (2011) Dawn Béraud et al. PARKINSONISM & RELATED DISORDERS
- Assessment of α-Synuclein Secretion in Mouse and Human Brain Parenchyma
- (2011) Evangelia Emmanouilidou et al. PLoS One
- Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism
- (2010) Guang Yang et al. BRAIN PATHOLOGY
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuroinflammation in Parkinson's disease: Its role in neuronal death and implications for therapeutic intervention
- (2009) Malú G. Tansey et al. NEUROBIOLOGY OF DISEASE
- Putting endotoxin to work for us: Monophosphoryl lipid A as a safe and effective vaccine adjuvant
- (2008) C. R. Casella et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
- (2007) Maryse Letiembre et al. NEUROBIOLOGY OF AGING
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now