Review of the effects of manufactured nanoparticles on mammalian target organs

Acute toxicological effects of zinc oxide nanoparticles in mice after intratracheal instillation

(2017) Dejun Wang et al.   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Toxicokinetics of titanium dioxide (TiO2) nanoparticles after inhalation in rats

(2017) Igor Pujalté et al.   TOXICOLOGY LETTERS

Toxicological evaluation of silver nanoparticles and silver nitrate in rats following 28 days of repeated oral exposure

(2016) Guangqiu Qin et al.   ENVIRONMENTAL TOXICOLOGY

Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles

(2016) Abderrahim Nemmar et al.   International Journal of Nanomedicine

Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity

(2016) Diana Couto et al.   JOURNAL OF APPLIED TOXICOLOGY

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation

(2016) Fan Zhang et al.   Journal of Neuroinflammation

Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague–Dawley rats

(2016) João Soeiro Teodoro et al.   Nanomedicine

Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure

(2016) Ilse Gosens et al.   Nanotoxicology

Visceral fat increase and signals of inflammation in adipose tissue after administration of titanium dioxide nanoparticles in mice

(2016) Adny H Silva et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Toxicity of nanosilver in intragastric studies: Biodistribution and metabolic effects

(2016) Olga D. Hendrickson et al.   TOXICOLOGY LETTERS

Nanotoxicity of poly(n-butylcyano-acrylate) nanoparticles at the blood–brain barrier, in human whole blood and in vivo

(2015) Marise Kolter et al.   JOURNAL OF CONTROLLED RELEASE

Nanomedicine for targeted photothermal cancer therapy: where are we now?

(2015) Feng Chen et al.   Nanomedicine

In vivo toxicity assessment of non-cadmium quantum dots in BALB/c mice

(2015) Guimiao Lin et al.   Nanomedicine-Nanotechnology Biology and Medicine

Intravenous administration of silver nanoparticles causes organ toxicity through intracellular ROS-related loss of inter-endothelial junction

(2015) Hua Guo et al.   Particle and Fibre Toxicology

Tissue distribution and acute toxicity of silver after single intravenous administration in mice: nano-specific and size-dependent effects

(2015) Camilla Recordati et al.   Particle and Fibre Toxicology

One-month persistence of inflammation and alteration of fibrotic marker and cytoskeletal proteins in rat kidney after Cd-doped silica nanoparticle instillation

(2015) Teresa Coccini et al.   TOXICOLOGY LETTERS

A 13-week repeated-dose oral toxicity and bioaccumulation of aluminum oxide nanoparticles in mice

(2014) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Toxicity of quantum dots on respiratory system

(2014) Tianshu Wu et al.   INHALATION TOXICOLOGY

Toxicological Properties of Nanomaterials

(2014) Mingyi Zhang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

An insight into silver nanoparticles bioavailability in rats

(2014) Javier Jiménez-Lamana et al.   Metallomics

Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats

(2014) Liesbeth Geraets et al.   Particle and Fibre Toxicology

In Vitro and In Vivo Biological Evaluation of O-Carboxymethyl Chitosan Encapsulated Metformin Nanoparticles for Pancreatic Cancer Therapy

(2014) K. S. Snima et al.   PHARMACEUTICAL RESEARCH

In Vitro Safety Evaluation of Nanomaterials^|^mdash;Cellular Response to Metal Oxide Nanoparticles^|^mdash;

(2014) Kazuo Isama   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Photosensitive Fluorescent Dye Contributes to Phototoxicity and Inflammatory Responses of Dye-doped Silica Nanoparticles in Cells and Mice

(2014) Yang Zhao et al.   Theranostics

Age Modulates Fe3O4Nanoparticles Liver Toxicity: Dose-Dependent Decrease in Mitochondrial Respiratory Chain Complexes Activities and Coupling in Middle-Aged as Compared to Young Rats

(2014) Yosra Baratli et al.   Biomed Research International

In Vivo Biodistribution and Toxicology of Carboxylated Graphene Quantum Dots

(2013) Md Nurunnabi et al.   ACS Nano

Peroxidase-mediated biodegradation of carbon nanotubes in vitro and in vivo

(2013) Gregg P. Kotchey et al.   ADVANCED DRUG DELIVERY REVIEWS

Molecular mechanism of titanium dioxide nanoparticles-induced oxidative injury in the brain of mice

(2013) Yuguan Ze et al.   CHEMOSPHERE

Comparison of toxicity of different nanorod-type TiO2polymorphsin vivoandin vitro

(2013) Eun-Jung Park et al.   JOURNAL OF APPLIED TOXICOLOGY

Modulation of the pharmacokinetics of zinc oxide nanoparticles and their fates in vivo

(2013) Hee-Jeong Paek et al.   Nanoscale

Oral, short-term exposure to titanium dioxide nanoparticles in Sprague-Dawley rat: focus on reproductive and endocrine systems and spleen

(2013) Roberta Tassinari et al.   Nanotoxicology

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

In Vivo Study of Spherical Gold Nanoparticles: Inflammatory Effects and Distribution in Mice

(2013) Hui Chen et al.   PLoS One

In vivo skin penetration and metabolic path of quantum dots

(2013) Lei Tang et al.   Science China-Life Sciences

A comprehensive in vitro and in vivo study of ZnO nanoparticles toxicity

(2013) Tae-Keun Hong et al.   Journal of Materials Chemistry B

Metabolism of Nanomaterials in Vivo: Blood Circulation and Organ Clearance

(2012) Bing Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Peptide-Functionalized Gold Nanorods Increase Liver Injury in Hepatitis

(2012) Matthias Bartneck et al.   ACS Nano

Acute toxicity and oxidative damage induced by silica nanorattle in vivo

(2012) ChangHui Fu et al.   CHINESE SCIENCE BULLETIN

Traffic-related fine and ultrafine particle exposures of professional drivers and illness: An opportunity to better link exposure science and epidemiology to address an occupational hazard?

(2012) L.D. Knibbs et al.   ENVIRONMENT INTERNATIONAL

Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats

(2012) K. Dziendzikowska et al.   JOURNAL OF APPLIED TOXICOLOGY

Demonstration of an Olfactory Bulb–Brain Translocation Pathway for ZnO Nanoparticles in Rodent Cells In Vitro and In Vivo

(2012) Yi-Yun Kao et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

In vivo toxicity, biodistribution, and clearance of glutathione-coated gold nanoparticles

(2012) Carrie A. Simpson et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanoparticle Transport from Mouse Vagina to Adjacent Lymph Nodes

(2012) Byron Ballou et al.   PLoS One

In vivo Imaging and Biodistribution of Multimodal Polymeric Nanoparticles Delivered to the Optic Nerve

(2012) James Harrison et al.   Small

Toxicology of nanoparticles

(2011) Andreas Elsaesser et al.   ADVANCED DRUG DELIVERY REVIEWS

A metabonomic analysis of organ specific response to USPIO administration

(2011) Jianghua Feng et al.   BIOMATERIALS

Toxicity of nanomaterials

(2011) Shahriar Sharifi et al.   CHEMICAL SOCIETY REVIEWS

Nervous system effects in rats on subacute exposure by lead-containing nanoparticles via the airways

(2011) Gábor Oszlánczi et al.   INHALATION TOXICOLOGY

Acute and subchronic dermal toxicity of nanosilver in guinea pig

(2011) Mitra Korani et al.   International Journal of Nanomedicine

Surface modified nevirapine nanosuspensions for viral reservoir targeting: In vitro and in vivo evaluation

(2011) Ranjita Shegokar et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation

(2011) Pablo Botella et al.   JOURNAL OF CONTROLLED RELEASE

Metabonomic Studies of Biochemical Changes in the Serum of Rats by Intratracheally Instilled TiO2 Nanoparticles

(2011) Meng Tang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

In vivobiodistribution of nanoparticles

(2011) Joao Paulo Mattos Almeida et al.   Nanomedicine

CdSe Quantum Dot (QD)-Induced Morphological and Functional Impairments to Liver in Mice

(2011) Wei Liu et al.   PLoS One

Aggravating Impact of Nanoparticles on Immune-Mediated Pulmonary Inflammation

(2011) Ken-Ichiro Inoue et al.   TheScientificWorldJOURNAL

Short term inhalation toxicity of a liquid aerosol of CdS/Cd(OH)2 core shell quantum dots in male Wistar rats

(2011) L. Ma-Hock et al.   TOXICOLOGY LETTERS

The kinetics of the tissue distribution of silver nanoparticles of different sizes

(2010) D.P.K. Lankveld et al.   BIOMATERIALS

Functional neurotoxicity of Mn-containing nanoparticles in rats

(2010) Gábor Oszlánczi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Targeted drug delivery into reversibly injured myocardium with silica nanoparticles: surface functionalization,  natural biodistribution, and acute toxicity

(2010) Galagudza   International Journal of Nanomedicine

Toxicologic effects of gold nanoparticles in vivo by different administration routes

(2010) Zhang   International Journal of Nanomedicine

Pulmonary Inflammation After Intraperitoneal Administration of Ultrafine Titanium Dioxide (TiO2) At Rest or in Lungs Primed with Lipopolysaccharide

(2010) Changsuk Moon et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Distribution and clearance of PEG-single-walled carbon nanotube cancer drug delivery vehicles in mice

(2010) Ashwin A Bhirde et al.   Nanomedicine

An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids

(2010) Jianghua Feng et al.   NANOTECHNOLOGY

Lung deposition and extrapulmonary translocation of nano-ceria after intratracheal instillation

(2010) Xiao He et al.   NANOTECHNOLOGY

Subchronic oral toxicity of silver nanoparticles

(2010) Yong Soon Kim et al.   Particle and Fibre Toxicology

Biodistribution of gold nanoparticles and gene expression changes in the liver and spleen after intravenous administration in rats

(2009) Suresh K. Balasubramanian et al.   BIOMATERIALS

Histological analysis of 70-nm silica particles-induced chronic toxicity in mice

(2009) Hikaru Nishimori et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

Inhibition of Macrophage Phagocytotic Activity by a Receptor-targeted Polymer Vesicle-based Drug Delivery Formulation of Pravastatin

(2009) Pavel Broz et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Potential Health Impact on Mice after Nasal Instillation of Nano-Sized Copper Particles and Their Translocation in Mice

(2009) Yang Liu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Pilot study of targeting magnetic carbon nanotubes to lymph nodes

(2009) Feng Yang et al.   Nanomedicine

Preparation, Characterization and Evaluation of Targeting Potential of Amphotericin B-Loaded Engineered PLGA Nanoparticles

(2009) Manoj Nahar et al.   PHARMACEUTICAL RESEARCH

In vivo Quantum-Dot Toxicity Assessment

(2009) Tanya S. Hauck et al.   Small

Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro

(2009) Helinor J. Johnston et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Pulmonary exposures to Sepiolite nanoclay particulates in rats: Resolution following multinucleate giant cell formation

(2009) David B. Warheit et al.   TOXICOLOGY LETTERS

Neurotoxicity of low-dose repeatedly intranasal instillation of nano- and submicron-sized ferric oxide particles in mice

(2008) Bing Wang et al.   JOURNAL OF NANOPARTICLE RESEARCH

Toxicological effects of multi-wall carbon nanotubes in rats

(2008) Aihong Liu et al.   JOURNAL OF NANOPARTICLE RESEARCH

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES

Bio-distribution and metabolic paths of silica coated CdSeS quantum dots

(2008) Zhen Chen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases

(2008) J WANG et al.   TOXICOLOGY LETTERS