Decoding the organization of spinal circuits that control locomotion

Primacy of Flexor Locomotor Pattern Revealed by Ancestral Reversion of Motor Neuron Identity

(2015) Timothy A. Machado et al.   CELL

Phenotypic Characterization of Speed-Associated Gait Changes in Mice Reveals Modular Organization of Locomotor Networks

(2015) Carmelo Bellardita et al.   CURRENT BIOLOGY

Peeling back the layers of locomotor control in the spinal cord

(2015) David L McLean et al.   CURRENT OPINION IN NEUROBIOLOGY

The basal ganglia downstream control of brainstem motor centres—an evolutionarily conserved strategy

(2015) Sten Grillner et al.   CURRENT OPINION IN NEUROBIOLOGY

Taking the next step: cortical contributions to the control of locomotion

(2015) Trevor Drew et al.   CURRENT OPINION IN NEUROBIOLOGY

Firing properties of Renshaw cells defined byChrna2are modulated by hyperpolarizing and small conductance ion currentsIhandISK

(2015) Sharn Perry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Organization of left-right coordination of neuronal activity in the mammalian spinal cord: Insights from computational modelling

(2015) Natalia A. Shevtsova et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetics: 10 years of microbial opsins in neuroscience

(2015) Karl Deisseroth   NATURE NEUROSCIENCE

High-throughput functional genomics using CRISPR–Cas9

(2015) Ophir Shalem et al.   NATURE REVIEWS GENETICS

Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity

(2015) Christopher A. Hinckley et al.   NEURON

Distinct Limb and Trunk Premotor Circuits Establish Laterality in the Spinal Cord

(2015) Cyrill Goetz et al.   NEURON

Cellular Level Brain Imaging in Behaving Mammals: An Engineering Approach

(2015) Elizabeth J.O. Hamel et al.   NEURON

Seeing the whole picture: A comprehensive imaging approach to functional mapping of circuits in behaving zebrafish

(2015) C.E. Feierstein et al.   NEUROSCIENCE

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

(2015) A. Zeisel et al.   SCIENCE

Muscle Spindle Feedback Directs Locomotor Recovery and Circuit Reorganization after Spinal Cord Injury

(2014) Aya Takeoka et al.   CELL

Neuromodulation in developing motor microcircuits

(2014) Keith T Sillar et al.   CURRENT OPINION IN NEUROBIOLOGY

Dynamics and plasticity of spinal locomotor circuits

(2014) Abdeljabbar El Manira   CURRENT OPINION IN NEUROBIOLOGY

The physiology of the pedunculopontine nucleus: implications for deep brain stimulation

(2014) E. Garcia-Rill et al.   JOURNAL OF NEURAL TRANSMISSION

Optogenetic Activation of Excitatory Premotor Interneurons Is Sufficient to Generate Coordinated Locomotor Activity in Larval Zebrafish

(2014) E. E. Ljunggren et al.   JOURNAL OF NEUROSCIENCE

Skilled reaching relies on a V2a propriospinal internal copy circuit

(2014) Eiman Azim et al.   NATURE

Brainstem nucleus MdV mediates skilled forelimb motor tasks

(2014) Maria Soledad Esposito et al.   NATURE

Separate Microcircuit Modules of Distinct V2a Interneurons and Motoneurons Control the Speed of Locomotion

(2014) Konstantinos Ampatzis et al.   NEURON

V1 and V2b Interneurons Secure the Alternating Flexor-Extensor Motor Activity Mice Require for Limbed Locomotion

(2014) Jingming Zhang et al.   NEURON

Respiratory Rhythm Generation In Vivo

(2014) Diethelm W. Richter et al.   PHYSIOLOGY

Rostro-Caudal Inhibition of Hindlimb Movements in the Spinal Cord of Mice

(2014) Vittorio Caggiano et al.   PLoS One

Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback

(2014) Turgay Akay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modular Organization of Axial Microcircuits in Zebrafish

(2014) M. W. Bagnall et al.   SCIENCE

Dopamine: a parallel pathway for the modulation of spinal locomotor networks

(2014) Simon A. Sharples et al.   Frontiers in Neural Circuits

Principles of interneuron development learned from Renshaw cells and the motoneuron recurrent inhibitory circuit

(2013) Francisco J. Alvarez et al.   Annals of the New York Academy of Sciences

Molecular, genetic, cellular, and network functions in the spinal cord and brainstem

(2013) Paul S.G. Stein   Annals of the New York Academy of Sciences

Dorsally derived spinal interneurons in locomotor circuits

(2013) Anna Vallstedt et al.   Annals of the New York Academy of Sciences

The Multifunctional Mesencephalic Locomotor Region

(2013) Dimitri Ryczko et al.   CURRENT PHARMACEUTICAL DESIGN

Pattern of Innervation and Recruitment of Different Classes of Motoneurons in Adult Zebrafish

(2013) K. Ampatzis et al.   JOURNAL OF NEUROSCIENCE

Functional Subpopulations of V3 Interneurons in the Mature Mouse Spinal Cord

(2013) J. Borowska et al.   JOURNAL OF NEUROSCIENCE

Neurophysiology of gait: From the spinal cord to the frontal lobe

(2013) Kaoru Takakusaki   MOVEMENT DISORDERS

Dual-mode operation of neuronal networks involved in left–right alternation

(2013) Adolfo E. Talpalar et al.   NATURE

Locomotor Rhythm Generation Linked to the Output of Spinal Shox2 Excitatory Interneurons

(2013) Kimberly J. Dougherty et al.   NEURON

Activity-Dependent Changes in Extracellular Ca2+ and K+ Reveal Pacemakers in the Spinal Locomotor-Related Network

(2013) Frédéric Brocard et al.   NEURON

Fast Silencing Reveals a Lost Role for Reciprocal Inhibition in Locomotion

(2013) Peter R. Moult et al.   NEURON

Circuits for Grasping: Spinal dI3 Interneurons Mediate Cutaneous Control of Motor Behavior

(2013) Tuan V. Bui et al.   NEURON

Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion

(2013) M. Hagglund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Multiple Classes of V0 Neurons in Zebrafish Spinal Cord: Progenitor Heterogeneity and Temporal Control of Neuronal Diversity

(2012) C. Satou et al.   JOURNAL OF NEUROSCIENCE

Neuronal activity in the isolated mouse spinal cord during spontaneous deletions in fictive locomotion: insights into locomotor central pattern generator organization

(2012) Guisheng Zhong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice

(2012) Lisa S. Andersson et al.   NATURE

Neuromodulation of Neuronal Circuits: Back to the Future

(2012) Eve Marder   NEURON

Origin of excitation underlying locomotion in the spinal circuit of zebrafish

(2012) E. Eklof-Ljunggren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decoding the rules of recruitment of excitatory interneurons in the adult zebrafish locomotor network

(2012) J. Ausborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular interactions underlying the specification of sensory neurons

(2012) Francois Lallemend et al.   TRENDS IN NEUROSCIENCES

Understanding the Rhythm of Breathing: So Near, Yet So Far

(2011) Jack L. Feldman et al.   Annual Review of Physiology

SnapShot: Spinal Cord Development

(2011) William A. Alaynick et al.   CELL

Neuromodulation and flexibility in Central Pattern Generator networks

(2011) Ronald M Harris-Warrick   CURRENT OPINION IN NEUROBIOLOGY

Motor antagonism exposed by spatial segregation and timing of neurogenesis

(2011) Marco Tripodi et al.   NATURE

Identification of Minimal Neuronal Networks Involved in Flexor-Extensor Alternation in the Mammalian Spinal Cord

(2011) Adolfo E. Talpalar et al.   NEURON

Locomotor Primitives in Newborn Babies and Their Development

(2011) N. Dominici et al.   SCIENCE

Impaired Respiratory and Body Temperature Control Upon Acute Serotonergic Neuron Inhibition

(2011) R. S. Ray et al.   SCIENCE

Frequency-dependent recruitment of V2a interneurons during fictive locomotion in the mouse spinal cord

(2011) Guisheng Zhong et al.   Nature Communications

Mechanisms of excitation of spinal networks by stimulation of the ventral roots

(2010) Michael J. O’Donovan et al.   Annals of the New York Academy of Sciences

Development and functional organization of spinal locomotor circuits

(2010) Ole Kiehn   CURRENT OPINION IN NEUROBIOLOGY

Genetically Defined Inhibitory Neurons in the Mouse Spinal Cord Dorsal Horn: A Possible Source of Rhythmic Inhibition of Motoneurons during Fictive Locomotion

(2010) J. M. Wilson et al.   JOURNAL OF NEUROSCIENCE

Specific Brainstem Neurons Switch Each Other into Pacemaker Mode to Drive Movement by Activating NMDA Receptors

(2010) W.-C. Li et al.   JOURNAL OF NEUROSCIENCE

Electrophysiological Characterization of V2a Interneurons and Their Locomotor-Related Activity in the Neonatal Mouse Spinal Cord

(2010) G. Zhong et al.   JOURNAL OF NEUROSCIENCE

Firing and Cellular Properties of V2a Interneurons in the Rodent Spinal Cord

(2010) K. J. Dougherty et al.   JOURNAL OF NEUROSCIENCE

Reciprocal Ia inhibition contributes to motoneuronal hyperpolarisation during the inactive phase of locomotion and scratching in the cat

(2010) S. S. Geertsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

(2010) Martin Hägglund et al.   NATURE NEUROSCIENCE

Monosynaptic Rabies Virus Reveals Premotor Network Organization and Synaptic Specificity of Cholinergic Partition Cells

(2010) Anna E. Stepien et al.   NEURON

Do Pacemakers Drive the Central Pattern Generator for Locomotion in Mammals?

(2010) Frédéric Brocard et al.   NEUROSCIENTIST

The role of inhibitory neurotransmission in locomotor circuits of the developing mammalian spinal cord

(2009) H. Nishimaru et al.   Acta Physiologica

The adaptation of limb kinematics to increasing walking speeds in freely moving mice 129/Sv and C57BL/6

(2009) Nadjet Serradj et al.   BEHAVIOURAL BRAIN RESEARCH

Measured motion: searching for simplicity in spinal locomotor networks

(2009) Sten Grillner et al.   CURRENT OPINION IN NEUROBIOLOGY

Transmitter-phenotypes of commissural interneurons in the lumbar spinal cord of newborn mice

(2009) Carlos Ernesto Restrepo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

In Mice Lacking V2a Interneurons, Gait Depends on Speed of Locomotion

(2009) S. A. Crone et al.   JOURNAL OF NEUROSCIENCE

Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of youngXenopustadpoles

(2009) Wen-Chang Li et al.   JOURNAL OF PHYSIOLOGY-LONDON

Circuits controlling vertebrate locomotion: moving in a new direction

(2009) Martyn Goulding   NATURE REVIEWS NEUROSCIENCE

A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity

(2009) Laskaro Zagoraiou et al.   NEURON

Transmitter phenotypes of commissural interneurons in the lamprey spinal cord

(2009) R. Mahmood et al.   NEUROSCIENCE

Thomas Graham Brown (1882–1965), Anders Lundberg (1920–), and the neural control of stepping

(2008) Douglas G. Stuart et al.   BRAIN RESEARCH REVIEWS

Roles for inhibition: studies on networks controlling swimming in young frog tadpoles

(2008) Alan Roberts et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY

Early Postnatal Development of Reciprocal Ia Inhibition in the Murine Spinal Cord

(2008) Zhi Wang et al.   JOURNAL OF NEUROPHYSIOLOGY

Hb9 Versus Type 2 Interneurons

(2008) Lea Ziskind-Conhaim et al.   JOURNAL OF NEUROPHYSIOLOGY

Asymmetric Operation of the Locomotor Central Pattern Generator in the Neonatal Mouse Spinal Cord

(2008) Toshiaki Endo et al.   JOURNAL OF NEUROPHYSIOLOGY

Persistent Sodium Current Contributes to Induced Voltage Oscillations in Locomotor-Related Hb9 Interneurons in the Mouse Spinal Cord

(2008) Lea Ziskind-Conhaim et al.   JOURNAL OF NEUROPHYSIOLOGY

Modulation of Transient and Persistent Inward Currents by Activation of Protein Kinase C in Spinal Ventral Neurons of the Neonatal Rat

(2008) Yue Dai et al.   JOURNAL OF NEUROPHYSIOLOGY

Excitatory and inhibitory intermediate zone interneurons in pathways from feline group I and II afferents: differences in axonal projections and input

(2008) B. A. Bannatyne et al.   JOURNAL OF PHYSIOLOGY-LONDON

Continuous shifts in the active set of spinal interneurons during changes in locomotor speed

(2008) David L McLean et al.   NATURE NEUROSCIENCE

Probing the Locomotor Conundrum: Descending the ‘V’ Interneuron Ladder

(2008) Anna E. Stepien et al.   NEURON

Genetic Ablation of V2a Ipsilateral Interneurons Disrupts Left-Right Locomotor Coordination in Mammalian Spinal Cord

(2008) Steven A. Crone et al.   NEURON

V3 Spinal Neurons Establish a Robust and Balanced Locomotor Rhythm during Walking

(2008) Ying Zhang et al.   NEURON

Neuromodulation and developmental plasticity in the locomotor system of anuran amphibians during metamorphosis

(2007) Keith T. Sillar et al.   BRAIN RESEARCH REVIEWS

Origin of excitatory drive to a spinal locomotor network

(2007) Alan Roberts et al.   BRAIN RESEARCH REVIEWS

Initiation of locomotion in lampreys

(2007) Réjean Dubuc et al.   BRAIN RESEARCH REVIEWS

Descending command systems for the initiation of locomotion in mammals

(2007) Larry M. Jordan et al.   BRAIN RESEARCH REVIEWS

Spinal interneuronal networks in the cat: Elementary components

(2007) Elzbieta Jankowska   BRAIN RESEARCH REVIEWS

Strategies for delineating spinal locomotor rhythm-generating networks and the possible role of Hb9 interneurones in rhythmogenesis

(2007) Robert M. Brownstone et al.   BRAIN RESEARCH REVIEWS