Aucubin protects mouse cochlear hair cells from cisplatin-induced ototoxicity via activation of the PI3K/AKT/STAT3 pathway
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Title
Aucubin protects mouse cochlear hair cells from cisplatin-induced ototoxicity via activation of the PI3K/AKT/STAT3 pathway
Authors
Keywords
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Journal
BIOCHEMICAL PHARMACOLOGY
Volume -, Issue -, Pages 115440
Publisher
Elsevier BV
Online
2023-01-30
DOI
10.1016/j.bcp.2023.115440
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Note: Only part of the references are listed.- TSLP protects against sepsis-induced liver injury by inducing autophagy via activation of the PI3K/Akt/STAT3 pathway
- (2022) He Wang et al. PATHOLOGY RESEARCH AND PRACTICE
- Neuroprotective effects of aucubin on hydrogen peroxide-induced toxicity in human neuroblastoma SH-SY5Y cells via the Nrf2/HO-1 pathway
- (2021) Ying chun Li et al. PHYTOMEDICINE
- Cisplatin Chemotherapy and Cochlear Damage: Otoprotective and Chemosensitization Properties of Polyphenols
- (2021) Anna Rita Fetoni et al. ANTIOXIDANTS & REDOX SIGNALING
- Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling
- (2021) Qingxiu Yao et al. MOLECULAR NEUROBIOLOGY
- Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
- (2021) Asal Jalal Abadi et al. PHYTOTHERAPY RESEARCH
- Inhibiting DNA methylation alleviates cisplatin-induced hearing loss by decreasing oxidative stress-induced mitochondria-dependent apoptosis via the LRP1–PI3K/AKT pathway
- (2021) Yingzi He et al. Acta Pharmaceutica Sinica B
- Trehalose protects against cisplatin-induced cochlear hair cell damage by activating TFEB-mediated autophagy
- (2021) Zhuangzhuang Li et al. BIOCHEMICAL PHARMACOLOGY
- The dual role of curcumin and ferulic acid in counteracting chemoresistance and cisplatin-induced ototoxicity
- (2020) Fabiola Paciello et al. Scientific Reports
- Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling
- (2020) Yang Di et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury
- (2020) Han Wang et al. Journal of Neuroinflammation
- Naringin attenuates cisplatin‐ and aminoglycoside‐induced hair cell injury in the zebrafish lateral line via multiple pathways
- (2020) Ming Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- BRAF inhibition protects against hearing loss in mice
- (2020) Matthew A. Ingersoll et al. Science Advances
- Pasireotide protects mammalian cochlear hair cells from gentamicin ototoxicity by activating the PI3K–Akt pathway
- (2019) Krystsina Kucharava et al. Cell Death & Disease
- Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/ HO ‐1 and AMPK signalling pathways
- (2019) Bingyu Shen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Aucubin, a natural iridoid glucoside, attenuates oxidative stress-induced testis injury by inhibiting JNK and CHOP activation via Nrf2 up-regulation
- (2019) Bo Ma et al. PHYTOMEDICINE
- Investigation of Astaxanthin Effect on Cisplatin Ototoxicity in Rats by Using Otoacoustic Emission, Total Antioxidant Capacity, and Histopathological Methods
- (2019) M. Emrah Kınal et al. ENT-EAR NOSE & THROAT JOURNAL
- Indigo fruits ingredient, aucubin protects against LPS-induced cardiac dysfunction in mice
- (2019) Ming Xia Duan et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Cisplatin-Induced Ototoxicity: Updates on Molecular Targets
- (2019) Erica Gentilin et al. TRENDS IN MOLECULAR MEDICINE
- A review of the pharmacology and toxicology of aucubin
- (2019) Xiangchang Zeng et al. FITOTERAPIA
- Aucubin, An Active Ingredient in Aucuba japonica, Prevents N-methyl-N-nitrosourea-induced Retinal Degeneration in Mice
- (2019) Eunsoo Jung et al. MOLECULES
- Aucubin protects against lipopolysaccharide-induced acute pulmonary injury through regulating Nrf2 and AMPK pathways
- (2018) Yan-Ling Qiu et al. BIOMEDICINE & PHARMACOTHERAPY
- CDK2 inhibitors as candidate therapeutics for cisplatin- and noise-induced hearing loss
- (2018) Tal Teitz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway
- (2018) Anna Rita Fetoni et al. Redox Biology
- The effects of oxidative stress on the development of atherosclerosis
- (2018) Mohsen Khosravi et al. BIOLOGICAL CHEMISTRY
- Are polyphenol antioxidants at the root of medicinal plant anti-cancer success?
- (2018) A.B. Oyenihi et al. JOURNAL OF ETHNOPHARMACOLOGY
- Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
- (2017) Sandeep Sheth et al. Frontiers in Cellular Neuroscience
- Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea
- (2017) Qianqian Chen et al. Stem Cell Reports
- Ototoxicity and cancer therapy
- (2016) Wendy Landier CANCER
- Comprehensive Audiometric Analysis of Hearing Impairment and Tinnitus After Cisplatin-Based Chemotherapy in Survivors of Adult-Onset Cancer
- (2016) Robert D. Frisina et al. JOURNAL OF CLINICAL ONCOLOGY
- The role of STAT3 in autophagy
- (2015) Liangkun You et al. Autophagy
- Rosmarinic acid up-regulates the noise-activated Nrf2/HO-1 pathway and protects against noise-induced injury in rat cochlea
- (2015) A.R. Fetoni et al. FREE RADICAL BIOLOGY AND MEDICINE
- Age-related hearing impairment—a risk factor and frailty marker for dementia and AD
- (2015) Francesco Panza et al. Nature Reviews Neurology
- Dexamethasone Protects Against Apoptotic Cell Death of Cisplatin-exposed Auditory Hair Cells In Vitro
- (2015) Christine T. Dinh et al. OTOLOGY & NEUROTOLOGY
- An integrated view of cisplatin-induced nephrotoxicity and ototoxicity
- (2015) Takatoshi Karasawa et al. TOXICOLOGY LETTERS
- Prevention of cisplatin-induced ototoxicity by the inhibition of gap junctional intercellular communication in auditory cells
- (2014) Yeon Ju Kim et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Platinum compounds in children with cancer
- (2013) Antonio Ruggiero et al. ANTI-CANCER DRUGS
- Understanding platinum-induced ototoxicity
- (2013) Thorsten Langer et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Neuroprotective properties of aucubin in diabetic rats and diabetic encephalopathy rats
- (2012) Hong Yu Xue et al. MOLECULAR BIOLOGY REPORTS
- Protective role of Nrf2 in age-related hearing loss and gentamicin ototoxicity
- (2011) Tomofumi Hoshino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effectiveness of different approaches for establishing cisplatin-induced cochlear lesions in mice
- (2010) Jingchun He et al. ACTA OTO-LARYNGOLOGICA
- Mechanisms of Cisplatin Nephrotoxicity
- (2010) Ronald P. Miller et al. Toxins
- Dexamethasone protects auditory hair cells against TNFα-initiated apoptosis via activation of PI3K/Akt and NFκB signaling
- (2009) Scott M. Haake et al. HEARING RESEARCH
- Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies
- (2009) Leonard P Rybak et al. TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE
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