Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation

RNA-Binding Proteins as Regulators of Migration, Invasion and Metastasis in Oral Squamous Cell Carcinoma

(2020) Jonas Weiße et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection

(2019) Hema Manjunath et al.   Cell Reports

Targeting c-Myc: JQ1 as a promising option for c-Myc-amplified esophageal squamous cell carcinoma

(2018) Jingyuan Wang et al.   CANCER LETTERS

Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma

(2017) Mitsuteru Natsuizaka et al.   Nature Communications

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

(2016) Endre Sebestyén et al.   GENOME RESEARCH

The hnRNP family: insights into their role in health and disease

(2016) Thomas Geuens et al.   HUMAN GENETICS

The increasing complexity of the ubiquitin code

(2016) Richard Yau et al.   NATURE CELL BIOLOGY

Control of the negative IREStrans-acting factor KHSRP by ubiquitination

(2016) Yu-An Kung et al.   NUCLEIC ACIDS RESEARCH

Transcriptional regulation of heterogeneous nuclear ribonucleoprotein K gene expression

(2015) Liqing He et al.   BIOCHIMIE

FBXO4 loss facilitates carcinogen induced papilloma development in mice

(2015) Zhaorui Lian et al.   CANCER BIOLOGY & THERAPY

hnRNP K Is a Haploinsufficient Tumor Suppressor that Regulates Proliferation and Differentiation Programs in Hematologic Malignancies

(2015) Miguel Gallardo et al.   CANCER CELL

Cytoplasmic Accumulation of Heterogeneous Nuclear Ribonucleoprotein K Strongly Promotes Tumor Invasion in Renal Cell Carcinoma Cells

(2015) Taiyo Otoshi et al.   PLoS One

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

(2014) Diane Moujalled et al.   HUMAN MOLECULAR GENETICS

Principles and Properties of Eukaryotic mRNPs

(2014) Sarah F. Mitchell et al.   MOLECULAR CELL

Dissecting the expression landscape of RNA-binding proteins in human cancers

(2014) Bobak Kechavarzi et al.   GENOME BIOLOGY

The FBXO4 Tumor Suppressor Functions as a Barrier to BrafV600E-Dependent Metastatic Melanoma

(2013) Eric K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

The Fbx4 Tumor Suppressor Regulates Cyclin D1 Accumulation and Prevents Neoplastic Transformation

(2011) L. P. Vaites et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation-dependent regulation of SCFFbx4 dimerization and activity involves a novel component, 14-3-3ɛ

(2011) O Barbash et al.   ONCOGENE

Higher Expression of the Heterogeneous Nuclear Ribonucleoprotein K in Melanoma

(2010) Fushi Wen et al.   ANNALS OF SURGICAL ONCOLOGY

Identification of the methylation preference region in heterogeneous nuclear ribonucleoprotein K by protein arginine methyltransferase 1 and its implication in regulating nuclear/cytoplasmic distribution

(2010) Yuan-I Chang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ

(2010) James E. Brownell et al.   MOLECULAR CELL

αB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells

(2010) Rong Hu et al.   Pigment Cell & Melanoma Research

Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer

(2009) P Barboro et al.   BRITISH JOURNAL OF CANCER

Heterogeneous ribonucleoprotein K is a marker of oral leukoplakia and correlates with poor prognosis of squamous cell carcinoma

(2009) Ajay Matta et al.   INTERNATIONAL JOURNAL OF CANCER

Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53

(2009) Renyuan Zhou et al.   INTERNATIONAL JOURNAL OF CANCER

Lysine 269 is essential for cyclin D1 ubiquitylation by the SCFFbx4/αB-crystallin ligase and subsequent proteasome-dependent degradation

(2009) O Barbash et al.   ONCOGENE

Mutations in Fbx4 Inhibit Dimerization of the SCFFbx4 Ligase and Contribute to Cyclin D1 Overexpression in Human Cancer

(2008) Olena Barbash et al.   CANCER CELL

Heterogeneous Ribonucleoprotein K and Thymidine Phosphorylase Are Independent Prognostic and Therapeutic Markers for Nasopharyngeal Carcinoma

(2008) L.-C. Chen et al.   CLINICAL CANCER RESEARCH