Antibody protection from SARS-CoV-2 respiratory tract exposure and infection

SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo

(2022) Kenrie P. Y. Hui et al.   NATURE

Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection

(2022) Alexander Chen et al.   BIOPHYSICAL JOURNAL

A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate response

(2022) Andreas C. Aristotelous et al.   JOURNAL OF THEORETICAL BIOLOGY

Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures

(2021) Michael Laue et al.   Scientific Reports

Self‐infection with speech aerosol may contribute to COVID‐19 severity

(2021) Poorna Kushalnagar et al.   JOURNAL OF INTERNAL MEDICINE

The total number and mass of SARS-CoV-2 virions

(2021) Ron Sender et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biophysical principles underpinning muco-trapping functions of antibodies

(2021) Alison Schaefer et al.   Human Vaccines & Immunotherapeutics

Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies

(2021) Stephen M. Kissler et al.   PLOS BIOLOGY

In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness

(2021) Ruian Ke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatially distributed infection increases viral load in a computational model of SARS-CoV-2 lung infection

(2021) Melanie E. Moses et al.   PLoS Computational Biology

LPS-binding IgG arrests actively motile Salmonella Typhimurium in gastrointestinal mucus

(2020) Holly A. Schroeder et al.   Mucosal Immunology

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

Virological assessment of hospitalized patients with COVID-2019

(2020) Roman Wölfel et al.   NATURE

A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract

(2020) Christian Quirouette et al.   PLoS Computational Biology

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

(2020) Zunlong Ke et al.   NATURE

Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19

(2020) Samuel K. Lai et al.   JOURNAL OF CONTROLLED RELEASE

Towards improved social distancing guidelines: Space and time dependence of virus transmission from speech-driven aerosol transport between two individuals

(2020) Fan Yang et al.   Physical Review Fluids

Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy

(2020) Carlos Cruz-Teran et al.   ADVANCED DRUG DELIVERY REVIEWS

Modeling Barrier Properties of Intestinal Mucus Reinforced with IgG and Secretory IgA against Motile Bacteria

(2019) Feifei Xu et al.   ACS Infectious Diseases

Antibody-Mediated Immobilization of Virions in Mucus

(2019) Melanie A. Jensen et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery

(2018) Jay M. Newby et al.   ADVANCED DRUG DELIVERY REVIEWS

ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus

(2018) Bing Yang et al.   JOURNAL OF INFECTIOUS DISEASES

A blueprint for robust crosslinking of mobile species in biogels with weakly adhesive molecular anchors

(2017) Jay Newby et al.   Nature Communications

Influenza-binding antibodies immobilise influenza viruses in fresh human airway mucus

(2016) Ying-Ying Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Absorption and Clearance of Pharmaceutical Aerosols in the Human Nose: Development of a CFD Model

(2016) Alex Rygg et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Using Computational Modeling To Optimize the Design of Antibodies That Trap Viruses in Mucus

(2015) Timothy Wessler et al.   ACS Infectious Diseases

Modeling of Virion Collisions in Cervicovaginal Mucus Reveals Limits on Agglutination as the Protective Mechanism of Secretory Immunoglobulin A

(2015) Alex Chen et al.   PLoS One

Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

(2014) Alex Chen et al.   BIOPHYSICAL JOURNAL

IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections

(2014) Y-Y Wang et al.   Mucosal Immunology

Modeling Neutralization Kinetics of HIV by Broadly Neutralizing Monoclonal Antibodies in Genital Secretions Coating the Cervicovaginal Mucosa

(2014) Scott A. McKinley et al.   PLoS One

Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques

(2013) C Moog et al.   Mucosal Immunology

The Mechanism of Breath Aerosol Formation

(2009) Graham Richard Johnson et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Human Immunodeficiency Virus Type 1 Is Trapped by Acidic but Not by Neutralized Human Cervicovaginal Mucus

(2009) S. K. Lai et al.   JOURNAL OF VIROLOGY

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Broadly Neutralizing Human Anti-HIV Antibody 2G12 Is Effective in Protection against Mucosal SHIV Challenge Even at Low Serum Neutralizing Titers

(2009) Ann J. Hessell et al.   PLoS Pathogens

Size distribution and sites of origin of droplets expelled from the human respiratory tract during expiratory activities

(2008) L. Morawska et al.   JOURNAL OF AEROSOL SCIENCE