Bioinformatic analysis as a first step to predict the compatibility of hematopoiesis and immune system genes between humans and pigs

Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood

(2022) Shuhei Miura et al.   XENOTRANSPLANTATION

Coagulation, inflammation, and CD46 transgene expression in neonatal porcine islet xenotransplantation

(2021) Mingqing Song et al.   XENOTRANSPLANTATION

The IL6-like Cytokine Family: Role and Biomarker Potential in Breast Cancer

(2021) Carlos Martínez-Pérez et al.   Journal of Personalized Medicine

A human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells

(2020) Fumiaki Jinnouchi et al.   BLOOD

Characterization of putative regulatory isoforms of porcine tumor necrosis factor receptor 2 in endothelial cells

(2020) Mireia Uribe‐Herranz et al.   XENOTRANSPLANTATION

Xenotransplantation in China: Present status

(2019) Yi Wang et al.   XENOTRANSPLANTATION

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

(2019) Guangyan Zhou et al.   NUCLEIC ACIDS RESEARCH

Pig endothelial protein C receptor is functionally compatible with the human protein C pathway

(2019) Evelyn J. Salvaris et al.   XENOTRANSPLANTATION

IS IL‐6 Receptor blockade (Tocilizumab) beneficial or detrimental to pig‐to‐baboon organ Xenotransplantation?

(2019) Guoqiang Zhang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Peripheral Tissue Chemokines: Homeostatic Control of Immune Surveillance T Cells

(2018) Michelle L. McCully et al.   TRENDS IN IMMUNOLOGY

Humanized mouse models to study pathophysiology and treatment of HIV infection

(2018) Guillemette Masse-Ranson et al.   Current Opinion in HIV and AIDS

Experimental Pig Heart Xenotransplantation - Recent Progress and Remaining Problems

(2018) David K.C. Cooper   ANNALS OF THORACIC SURGERY

Consistent success in life-supporting porcine cardiac xenotransplantation

(2018) Matthias Längin et al.   NATURE

VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche

(2018) Dantong Li et al.   NATURE

Development of Severe Combined Immunodeficient (SCID) Pig Models for Translational Cancer Modeling: Future Insights on How Humanized SCID Pigs Can Improve Preclinical Cancer Research

(2018) Adeline N. Boettcher et al.   Frontiers in Oncology

Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9

(2018) Peter J. Cowan et al.   Current Opinion in Organ Transplantation

Genetically Modified Pigs as Organ Donors for Xenotransplantation

(2017) Magdalena Hryhorowicz et al.   MOLECULAR BIOTECHNOLOGY

Role of human CD200 overexpression in pig-to-human xenogeneic immune response compared with human CD47 overexpression

(2017) Ji-Jing Yan et al.   TRANSPLANTATION

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

Hematopoietic stem cell lineage specification

(2016) Marie Pouzolles et al.   CURRENT OPINION IN HEMATOLOGY

Microenvironmental regulation of hematopoietic stem cells and its implications in leukemogenesis

(2016) Madhav Seshadri et al.   CURRENT OPINION IN HEMATOLOGY

Production of heterozygous alpha 1,3-galactosyltransferase (GGTA1) knock-out transgenic miniature pigs expressing human CD39

(2016) Kimyung Choi et al.   TRANSGENIC RESEARCH

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

(2016) Muhammad M. Mohiuddin et al.   Nature Communications

BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs

(2015) Felipe A. Simão et al.   BIOINFORMATICS

The role of genetically engineered pigs in xenotransplantation research

(2015) David KC Cooper et al.   JOURNAL OF PATHOLOGY

Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Pre-clinical heterotopic intrathoracic heart xenotransplantation: a possibly useful clinical technique

(2015) Jan-Michael Abicht et al.   XENOTRANSPLANTATION

Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model

(2015) Laura Higginbotham et al.   XENOTRANSPLANTATION

Transgenic Expression of Human CD47 Markedly Increases Engraftment in a Murine Model of Pig-to-Human Hematopoietic Cell Transplantation

(2014) A. Tena et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Chemokines and Chemokine Receptors: Positioning Cells for Host Defense and Immunity

(2014) Jason W. Griffith et al.   Annual Review of Immunology

Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation

(2014) Muhammad M. Mohiuddin et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment

(2014) Sofieke Klamer et al.   Cell Adhesion & Migration

Structural and functional annotation of the porcine immunome

(2013) Harry D Dawson et al.   BMC GENOMICS

The suppression of inflammatory macrophage-mediated cytotoxicity and proinflammatory cytokine production by transgenic expression of HLA-E

(2013) Akira Maeda et al.   TRANSPLANT IMMUNOLOGY

Effector Mechanisms of Rejection

(2013) A. Moreau et al.   Cold Spring Harbor Perspectives in Medicine

Generation and Characterization of Human Heme Oxygenase-1 Transgenic Pigs

(2012) Hye-Jung Yeom et al.   PLoS One

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

The sequence and analysis of a Chinese pig genome

(2012) Xiaodong Fang et al.   GigaScience

Controlling coagulation dysregulation in xenotransplantation

(2011) Peter J Cowan et al.   Current Opinion in Organ Transplantation

Role of secreted factors in the regulation of hematopoietic stem cells by the bone marrow microenvironment

(2011) Pawandeep Kaur-Bollinger   Frontiers in Bioscience-Landmark

Clinical xenotransplantation: the next medical revolution?

(2011) Burcin Ekser et al.   LANCET

Genetic modifications of pigs for medicine and agriculture

(2011) Jeffrey J. Whyte et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Functional CD47/signal regulatory protein alpha (SIRPα) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

(2011) Nicolas Legrand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of soluble and membrane-bound isoforms of porcine tumor necrosis factor receptor 2

(2011) Mireia Uribe-Herranz et al.   XENOTRANSPLANTATION

Coagulation, platelet activation and thrombosis in xenotransplantation

(2010) Moritz Schmelzle et al.   Current Opinion in Organ Transplantation

DOG 1.0: illustrator of protein domain structures

(2009) Jian Ren et al.   CELL RESEARCH

Complement activation and coagulation in xenotransplantation

(2009) Peter J Cowan et al.   IMMUNOLOGY AND CELL BIOLOGY

Transgenic expression of the human A20 gene in cloned pigs provides protection against apoptotic and inflammatory stimuli

(2009) Marianne Oropeza et al.   XENOTRANSPLANTATION

Pig Thrombomodulin Binds Human Thrombin but Is a Poor Cofactor for Activation of Human Protein C and TAFI

(2008) J. C. Roussel et al.   AMERICAN JOURNAL OF TRANSPLANTATION

genBlastA: Enabling BLAST to identify homologous gene sequences

(2008) R. She et al.   GENOME RESEARCH

Coagulation dysregulation as a barrier to xenotransplantation in the primate

(2008) Chih Che Lin et al.   TRANSPLANT IMMUNOLOGY

Recombinant pig TFPI efficiently regulates human tissue factor pathways

(2008) K. F. Eddy Lee et al.   XENOTRANSPLANTATION