Identification of two migratory colon ILC2 populations differentially expressing IL-17A and IL-5/IL-13

Neuropilin-1 mediates lung tissue-specific control of ILC2 function in type 2 immunity

(2022) Jingjing Zhang et al.   NATURE IMMUNOLOGY

Neuropilin-1 flags lung-resident type 2 innate lymphoid cells

(2022) Hergen Spits   NATURE IMMUNOLOGY

ILC2s – development, divergence, dispersal

(2022) Roberto R Ricardo-Gonzalez et al.   CURRENT OPINION IN IMMUNOLOGY

Tissue-specific transcriptional imprinting and heterogeneity in human innate lymphoid cells revealed by full-length single-cell RNA-sequencing

(2021) Luca Mazzurana et al.   CELL RESEARCH

Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity

(2021) Jinxin Qiu et al.   Mucosal Immunology

Antigen-presenting innate lymphoid cells orchestrate neuroinflammation

(2021) John B. Grigg et al.   NATURE

BATF acts as an essential regulator of IL-25–responsive migratory ILC2 cell fate and function

(2020) Mindy M. Miller et al.   Science Immunology

Innate lymphoid cells control signaling circuits to regulate tissue-specific immunity

(2020) Christoph S. N. Klose et al.   CELL RESEARCH

Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity

(2020) Anne-Laure Flamar et al.   IMMUNITY

Tissue-Resident Group 2 Innate Lymphoid Cells Differentiate by Layered Ontogeny and In Situ Perinatal Priming

(2019) Christoph Schneider et al.   IMMUNITY

Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation

(2019) Hiroyuki Nagashima et al.   IMMUNITY

IL-17–producing ST2 + group 2 innate lymphoid cells play a pathogenic role in lung inflammation

(2018) Ting Cai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lung inflammation originating in the gut

(2018) Jenny Mjösberg et al.   SCIENCE

S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense

(2018) Yuefeng Huang et al.   SCIENCE

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

Tissue signals imprint ILC2 identity with anticipatory function

(2018) Roberto R. Ricardo-Gonzalez et al.   NATURE IMMUNOLOGY

ILC2s — resident lymphocytes pre-adapted to a specific tissue or migratory effectors that adapt to where they move?

(2018) Ronald N Germain et al.   CURRENT OPINION IN IMMUNOLOGY

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

(2016) Charlotte L. Scott et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis

(2016) Christoph S N Klose et al.   NATURE IMMUNOLOGY

Transcription factor Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate

(2016) Xiaodi Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation

(2015) Ari B. Molofsky et al.   IMMUNITY

The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection

(2015) Claudia X. Dominguez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional repressor ZEB2 promotes terminal differentiation of CD8 + effector and memory T cell populations during infection

(2015) Kyla D. Omilusik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

(2015) Mary J. van Helden et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

Interferon and IL-27 antagonize the function of group 2 innate lymphoid cells and type 2 innate immune responses

(2015) Kazuyo Moro et al.   NATURE IMMUNOLOGY

Tissue residency of innate lymphoid cells in lymphoid and nonlymphoid organs

(2015) G. Gasteiger et al.   SCIENCE

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

(2014) Christopher J. Oliphant et al.   IMMUNITY

The Transcription Factor GATA3 Is Critical for the Development of All IL-7Rα-Expressing Innate Lymphoid Cells

(2014) Ryoji Yagi et al.   IMMUNITY

Type 2 Innate Lymphoid Cells Drive CD4+ Th2 Cell Responses

(2014) A. S. Mirchandani et al.   JOURNAL OF IMMUNOLOGY

IL-25-responsive, lineage-negative KLRG1hi cells are multipotential ‘inflammatory’ type 2 innate lymphoid cells

(2014) Yuefeng Huang et al.   NATURE IMMUNOLOGY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction

(2013) Jillian L. Barlow et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

(2013) Christoph S. N. Klose et al.   NATURE

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Control of TH17 cells occurs in the small intestine

(2011) Enric Esplugues et al.   NATURE

Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology

(2010) Sofia Buonocore et al.   NATURE

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells

(2008) Stephanie L Sanos et al.   NATURE IMMUNOLOGY