GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton

Mitochondria and calcium defects correlate with axonal dysfunction in GDAP1-related Charcot-Marie-Tooth mouse model

(2021) Azahara Civera-Tregón et al.   NEUROBIOLOGY OF DISEASE

Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death

(2021) Lena Hoffmann et al.   Cell Death & Disease

Structural and functional divergence of GDAP1 from the glutathione S‐transferase superfamily

(2020) Matthew R. Googins et al.   FASEB JOURNAL

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Post-translational S-glutathionylation of cofilin increases actin cycling during cocaine seeking

(2019) Anna Kruyer et al.   PLoS One

Differential requirements of tubulin genes in mammalian forebrain development

(2019) Elizabeth Bittermann et al.   PLoS Genetics

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

(2017) Rajarshi Chakrabarti et al.   JOURNAL OF CELL BIOLOGY

Correction: Actin visualization at a glance

(2017) Michael Melak et al.   JOURNAL OF CELL SCIENCE

Evaluation of FASP, SP3, and iST Protocols for Proteomic Sample Preparation in the Low Microgram Range

(2017) Malte Sielaff et al.   JOURNAL OF PROTEOME RESEARCH

Cofilin1-dependent actin dynamics control DRP1-mediated mitochondrial fission

(2017) Katharina Rehklau et al.   Cell Death & Disease

CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration

(2017) Paloma González-Sánchez et al.   Scientific Reports

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

Multiple dynamin family members collaborate to drive mitochondrial division

(2016) Jason E. Lee et al.   NATURE

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutathione-conjugating and membrane-remodeling activity of GDAP1 relies on amphipathic C-terminal domain

(2016) Nina Huber et al.   Scientific Reports

BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

(2016) Tomoki Yoshida et al.   Scientific Reports

Redox regulation of cytoskeletal dynamics during differentiation and de-differentiation

(2015) Manuela Gellert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites

(2015) Wei-ke Ji et al.   eLife

Taurine chloramine-induced inactivation of cofilin protein through methionine oxidation

(2014) Shen Luo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Junctophilin-1 is a modifier gene of GDAP1-related Charcot–Marie–Tooth disease

(2014) David Pla-Martín et al.   HUMAN MOLECULAR GENETICS

MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity

(2014) Maria Patron et al.   MOLECULAR CELL

Ultrasensitive proteome analysis using paramagnetic bead technology

(2014) C. S. Hughes et al.   Molecular Systems Biology

Imaging intraorganellar Ca2+ at subcellular resolution using CEPIA

(2014) Junji Suzuki et al.   Nature Communications

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Charcot-Marie-Tooth disease-associated mutants of GDAP1 dissociate its roles in peroxisomal and mitochondrial fission

(2013) Nina Huber et al.   EMBO REPORTS

A new locus for X-linked dominant Charcot-Marie-Tooth disease (CMTX6) is caused by mutations in the pyruvate dehydrogenase kinase isoenzyme 3 (PDK3) gene

(2013) M. L. Kennerson et al.   HUMAN MOLECULAR GENETICS

BSCL2/seipin regulates adipogenesis through actin cytoskeleton remodelling

(2013) Wulin Yang et al.   HUMAN MOLECULAR GENETICS

Proteome-Wide Characterization of the RNA-Binding Protein RALY-Interactome Using the in Vivo-Biotinylation-Pulldown-Quant (iBioPQ) Approach

(2013) Stefan Tenzer et al.   JOURNAL OF PROTEOME RESEARCH

Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry

(2013) David Pla-Martín et al.   NEUROBIOLOGY OF DISEASE

Derivation and Expansion Using Only Small Molecules of Human Neural Progenitors for Neurodegenerative Disease Modeling

(2013) Peter Reinhardt et al.   PLoS One

Cofilin Oligomer Formation Occurs In Vivo and Is Regulated by Cofilin Phosphorylation

(2013) Pankaj Goyal et al.   PLoS One

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

(2013) F. Korobova et al.   SCIENCE

The intracellular redox state is a core determinant of mitochondrial fusion

(2012) Timothy Shutt et al.   EMBO REPORTS

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Cofilin/Twinstar Phosphorylation Levels Increase in Response to Impaired Coenzyme A Metabolism

(2012) Katarzyna Siudeja et al.   PLoS One

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential

(2011) Rebecca Noack et al.   HUMAN MOLECULAR GENETICS

Charcot-Marie-Tooth-related GeneGDAP1Complements Cell Cycle Delay at G2/M Phase inSaccharomyces cerevisiae fis1Gene-defective Cells

(2011) Anna Estela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Actin specifically controls cell growth, migration, and the G-actin pool

(2011) Tina M. Bunnell et al.   MOLECULAR BIOLOGY OF THE CELL

INF2Mutations in Charcot–Marie–Tooth Disease with Glomerulopathy

(2011) Olivia Boyer et al.   NEW ENGLAND JOURNAL OF MEDICINE

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Tissue-Autonomous Function of Drosophila Seipin in Preventing Ectopic Lipid Droplet Formation

(2011) Yuan Tian et al.   PLoS Genetics

Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels

(2010) Marta Giacomello et al.   MOLECULAR CELL

Imaging Interorganelle Contacts and Local Calcium Dynamics at the ER-Mitochondrial Interface

(2010) György Csordás et al.   MOLECULAR CELL

SEIPIN S90L Mutation in an Italian family with CMT2/dHMN and pyramidal signs

(2010) M. Luigetti et al.   MUSCLE & NERVE

Seipin deficiency alters fatty acid Δ9 desaturation and lipid droplet formation in Berardinelli-Seip congenital lipodystrophy

(2009) Emilie Boutet et al.   BIOCHIMIE

Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

(2009) Fábio Klamt et al.   NATURE CELL BIOLOGY

GDAP1 mutations differ in their effects on mitochondrial dynamics and apoptosis depending on the mode of inheritance

(2009) Axel Niemann et al.   NEUROBIOLOGY OF DISEASE

Targeting and Function of the Mitochondrial Fission Factor GDAP1 Are Dependent on Its Tail-Anchor

(2009) Konstanze M. Wagner et al.   PLoS One

Oxidation of Cofilin Mediates T Cell Hyporesponsiveness under Oxidative Stress Conditions

(2008) Martin Klemke et al.   IMMUNITY

A novel GDAP1 Q218E mutation in autosomal dominant Charcot-Marie-Tooth disease

(2008) Ki Wha Chung et al.   JOURNAL OF HUMAN GENETICS