Trans-epithelial fluid flow and mechanics of epithelial morphogenesis

The correlation between cell and nucleus size is explained by an eukaryotic cell growth model

(2022) Yufei Wu et al.   PLoS Computational Biology

Kidney epithelial cells are active mechano-biological fluid pumps

(2022) Mohammad Ikbal Choudhury et al.   Nature Communications

A mechano-osmotic feedback couples cell volume to the rate of cell deformation

(2022) Larisa Venkova et al.   eLife

The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model

(2021) Khaoula Talbi et al.   FASEB JOURNAL

Cell fate coordinates mechano-osmotic forces in intestinal crypt formation

(2021) Qiutan Yang et al.   NATURE CELL BIOLOGY

Quantitative modelling of amino acid transport and homeostasis in mammalian cells

(2021) Gregory Gauthier-Coles et al.   Nature Communications

Physical basis for the determination of lumen shape in a simple epithelium

(2021) Claudia G. Vasquez et al.   Nature Communications

A hydro-osmotic coarsening theory of biological cavity formation

(2021) Mathieu Le Verge-Serandour et al.   PLoS Computational Biology

Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis

(2021) Akankshi Munjal et al.   CELL

Pressure sensing through Piezo channels controls whether cells migrate with blebs or pseudopods

(2020) Nishit Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrauterine Pressures Adjusted by Reichert’s Membrane Are Crucial for Early Mouse Morphogenesis

(2020) Yoko Ueda et al.   Cell Reports

Targeting chloride transport in autosomal dominant polycystic kidney disease

(2020) François Jouret et al.   CELLULAR SIGNALLING

Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo

(2020) Ines Cabrita et al.   Nature Communications

Embryo Size Regulates the Timing and Mechanism of Pluripotent Tissue Morphogenesis

(2020) Lorenzo C. Orietti et al.   Stem Cell Reports

Myosin II governs intracellular pressure and traction by distinct tropomyosin-dependent mechanisms

(2019) Kimheak Sao et al.   MOLECULAR BIOLOGY OF THE CELL

Hydraulic control of mammalian embryo size and cell fate

(2019) Chii Jou Chan et al.   NATURE

Hydraulic fracturing and active coarsening position the lumen of the mouse blastocyst

(2019) Julien G. Dumortier et al.   SCIENCE

Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area

(2019) Runchen Zhao et al.   Science Advances

YAP and TAZ regulate cell volume

(2019) Nicolas A. Perez-Gonzalez et al.   JOURNAL OF CELL BIOLOGY

Fluid pumping and active flexoelectricity can promote lumen nucleation in cell assemblies

(2019) Charlie Duclut et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On the energy efficiency of cell migration in diverse physical environments

(2019) Yizeng Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness

(2019) Elisa Agnese Nigro et al.   Scientific Reports

Lumen Expansion Facilitates Epiblast-Primitive Endoderm Fate Specification during Mouse Blastocyst Formation

(2019) Allyson Quinn Ryan et al.   DEVELOPMENTAL CELL

Microscale pressure measurements based on an immiscible fluid/fluid interface

(2019) Jing Yang et al.   Scientific Reports

Electromechanics and Volume Dynamics in Nonexcitable Tissue Cells

(2018) Florence Yellin et al.   BIOPHYSICAL JOURNAL

Transition from Actin-Driven to Water-Driven Cell Migration Depends on External Hydraulic Resistance

(2018) Yizeng Li et al.   BIOPHYSICAL JOURNAL

A RhoA–YAP–c-Myc signaling axis promotes the development of polycystic kidney disease

(2018) Jing Cai et al.   GENES & DEVELOPMENT

Physics of lumen growth

(2018) Sabyasachi Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Tension and Mechanical Regulation of Cell Volume

(2018) Nicolas Perez Gonzalez et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay

(2018) Karolis Leonavicius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active superelasticity in three-dimensional epithelia of controlled shape

(2018) Ernest Latorre et al.   NATURE

Polycystic kidney disease

(2018) Carsten Bergmann et al.   Nature Reviews Disease Primers

Cell mechanics: a dialogue

(2017) Jiaxiang Tao et al.   REPORTS ON PROGRESS IN PHYSICS

Computational models of airway branching morphogenesis

(2017) Victor D. Varner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A comprehensive review on energy efficiency enhancement initiatives in centrifugal pumping system

(2016) Vishnu Kalaiselvan Arun Shankar et al.   APPLIED ENERGY

Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo

(2016) Véronique Gebala et al.   NATURE CELL BIOLOGY

The importance of total kidney volume in evaluating progression of polycystic kidney disease

(2016) Jared J. Grantham et al.   Nature Reviews Nephrology

Active Biochemical Regulation of Cell Volume and a Simple Model of Cell Tension Response

(2015) Jiaxiang Tao et al.   BIOPHYSICAL JOURNAL

Effects of Hydrostatic Pressure on Carcinogenic Properties of Epithelia

(2015) Shinsaku Tokuda et al.   PLoS One

Self-Organizing Properties of Mouse Pluripotent Cells Initiate Morphogenesis upon Implantation

(2014) Ivan Bedzhov et al.   CELL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Parasympathetic Innervation Regulates Tubulogenesis in the Developing Salivary Gland

(2014) Pavel I. Nedvetsky et al.   DEVELOPMENTAL CELL

Mechanical control of notochord morphogenesis by extra-embryonic tissues in mouse embryos

(2014) Yu Imuta et al.   MECHANISMS OF DEVELOPMENT

Molecular mechanisms of de novo lumen formation

(2014) Sara Sigurbjörnsdóttir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Volumetric Deformation of Live Cells Induced by Pressure-Activated Cross-Membrane Ion Transport

(2014) T. H. Hui et al.   PHYSICAL REVIEW LETTERS

Generation of compartmentalized pressure by a nuclear piston governs cell motility in a 3D matrix

(2014) R. J. Petrie et al.   SCIENCE

Traction force microscopy in physics and biology

(2014) Robert W. Style et al.   Soft Matter

Cellular Pressure and Volume Regulation and Implications for Cell Mechanics

(2013) Hongyuan Jiang et al.   BIOPHYSICAL JOURNAL

Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments

(2013) H. V. Prentice-Mott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiology of Epithelial Chloride and Fluid Secretion

(2013) R. A. Frizzell et al.   Cold Spring Harbor Perspectives in Medicine

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Surface fluid absorption and secretion in small airways

(2012) A. K. M. Shamsuddin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Molecular Mechanism of Pancreatic and Salivary Gland Fluid and HCO3− Secretion

(2012) Min Goo Lee et al.   PHYSIOLOGICAL REVIEWS

Amnion formation in the mouse embryo: the single amniochorionic fold model

(2011) Paulo NG Pereira et al.   BMC DEVELOPMENTAL BIOLOGY

Hypertension in Autosomal Dominant Polycystic Kidney Disease

(2010) Arlene B. Chapman et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Cytoskeletal Cross-linking and Bundling in Motor-Independent Contraction

(2010) Sean X. Sun et al.   CURRENT BIOLOGY

The cell biology of polycystic kidney disease

(2010) Hannah C. Chapin et al.   JOURNAL OF CELL BIOLOGY

Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding

(2010) Martin P. Stewart et al.   NATURE

Cell adhesion: integrating cytoskeletal dynamics and cellular tension

(2010) J. Thomas Parsons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polycystin-1 and -2 Dosage Regulates Pressure Sensing

(2009) Reza Sharif-Naeini et al.   CELL

Morphogenesis of epithelial tubes: Insights into tube formation, elongation, and elaboration

(2009) Deborah J. Andrew et al.   DEVELOPMENTAL BIOLOGY

Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis

(2008) Fernando Martín-Belmonte et al.   CURRENT BIOLOGY

Small-Molecule CFTR Inhibitors Slow Cyst Growth in Polycystic Kidney Disease

(2008) B. Yang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tracheal occlusion increases the rate of epithelial branching of embryonic mouse lung via the FGF10-FGFR2b-Sprouty2 pathway

(2007) Mathieu Unbekandt et al.   MECHANISMS OF DEVELOPMENT