Reversible modification of mitochondrial ADP/ATP translocases by paired Legionella effector proteins

Legionella pneumophila modulates host energy metabolism by ADP-ribosylation of ADP/ATP translocases

(2022) Jiaqi Fu et al.   eLife

A Legionella effector ADP-ribosyltransferase inactivates glutamate dehydrogenase

(2021) Miles H. Black et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4

(2021) Robert G. Hammond et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11

(2021) Zilin Li et al.   NATURE

Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche

(2021) Pedro Escoll et al.   eLife

Structural and Functional Characterization of Legionella pneumophila Effector MavL

(2021) Kevin Voth et al.   Biomolecules

(ADP-ribosyl)hydrolases: structure, function, and biology

(2020) Johannes Gregor Matthias Rack et al.   GENES & DEVELOPMENT

Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination

(2020) Fujie Yan et al.   MOLECULAR CELL

Molecular basis for the MacroD1-mediated hydrolysis of ADP-ribosylation

(2020) Xiaoyun Yang et al.   DNA REPAIR

Bacterial virulence mediated by orthogonal post-translational modification

(2020) Kaitlin A. Chambers et al.   Nature Chemical Biology

Structural and biochemical evidence supporting poly ADP-ribosylation in the bacterium Deinococcus radiodurans

(2019) Chao-Cheng Cho et al.   Nature Communications

A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy

(2019) Yue Xu et al.   CELL

HH-suite3 for fast remote homology detection and deep protein annotation

(2019) Martin Steinegger et al.   BMC BIOINFORMATICS

Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB

(2019) Donghyuk Shin et al.   MOLECULAR CELL

Deubiquitination of phosphoribosyl-ubiquitin conjugates by phosphodiesterase-domain–containing Legionella effectors

(2019) Min Wan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DALI and the persistence of protein shape

(2019) Liisa Holm   PROTEIN SCIENCE

The SLC25 Mitochondrial Carrier Family: Structure and Mechanism

(2019) Jonathan J. Ruprecht et al.   TRENDS IN BIOCHEMICAL SCIENCES

Legionella pneumophila regulates the activity of UBE 2N by deamidase‐mediated deubiquitination

(2019) Ninghai Gan et al.   EMBO JOURNAL

LotA, a Legionella deubiquitinase, has dual catalytic activity and contributes to intracellular growth

(2018) Tomoko Kubori et al.   CELLULAR MICROBIOLOGY

Metabolic reprogramming of host cells upon bacterial infection: Why shift to a Warburg-like metabolism?

(2018) Pedro Escoll et al.   FEBS Journal

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination

(2018) Sissy Kalayil et al.   NATURE

MultipleLegionella pneumophilaeffector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries

(2017) Stephanie R. Shames et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDBsum: Structural summaries of PDB entries

(2017) Roman A. Laskowski et al.   PROTEIN SCIENCE

Structural and functional analysis of Oceanobacillus iheyensis macrodomain reveals a network of waters involved in substrate binding and catalysis

(2017) Rubén Zapata-Pérez et al.   Open Biology

Macrodomains: Structure, Function, Evolution, and Catalytic Activities

(2016) Johannes Gregor Matthias Rack et al.   Annual Review of Biochemistry

Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination

(2016) Sagar Bhogaraju et al.   CELL

The Type IVB secretion system: an enigmatic chimera

(2016) Tomoko Kubori et al.   CURRENT OPINION IN MICROBIOLOGY

Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila

(2016) Malene L Urbanus et al.   Molecular Systems Biology

Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

(2016) Jiazhang Qiu et al.   NATURE

Legionella pneumophilaS1P-lyase targets host sphingolipid metabolism and restrains autophagy

(2016) Monica Rolando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages

(2016) Arwa Abu Khweek et al.   PLoS One

Toxicity and SidJ-Mediated Suppression of Toxicity Require Distinct Regions in the SidE Family of Legionella pneumophila Effectors

(2015) James C. Havey et al.   INFECTION AND IMMUNITY

Structure and function of the ARH family of ADP-ribosyl-acceptor hydrolases

(2014) Masato Mashimo et al.   DNA REPAIR

Novel bacterial ADP-ribosylating toxins: structure and function

(2014) Nathan C. Simon et al.   NATURE REVIEWS MICROBIOLOGY

Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

(2013) Florian Rosenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A family of macrodomain proteins reverses cellular mono-ADP-ribosylation

(2013) Gytis Jankevicius et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bacterial Subversion of Host Innate Immune Pathways

(2013) L. A. Baxt et al.   SCIENCE

Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains

(2013) Alexandra H. Forst et al.   STRUCTURE

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structures of the Human Poly (ADP-Ribose) Glycohydrolase Catalytic Domain Confirm Catalytic Mechanism and Explain Inhibition by ADP-HPD Derivatives

(2012) Julie A. Tucker et al.   PLoS One

Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

(2012) Pavel Dolezal et al.   PLoS Pathogens

Mitochondrial elongation during autophagy

(2011) Ligia C. Gomes et al.   Autophagy

Identification of Macrodomain Proteins as NovelO-Acetyl-ADP-ribose Deacetylases

(2011) Dawei Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Legionella pneumophila SidD is a deAMPylase that modifies Rab1

(2011) Yunhao Tan et al.   NATURE

The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase

(2011) Dea Slade et al.   NATURE

De-AMPylation of the Small GTPase Rab1 by the Pathogen Legionella pneumophila

(2011) M. R. Neunuebel et al.   SCIENCE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ADP-ribosylation of arginine

(2010) Sabrina Laing et al.   AMINO ACIDS

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

(2010) Tomoko Kubori et al.   PLoS Pathogens

Decision-making in structure solution using Bayesian estimates of map quality: thePHENIX AutoSolwizard

(2009) Thomas C. Terwilliger et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ALegionellaeffector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria

(2009) Elena Degtyar et al.   CELLULAR MICROBIOLOGY

Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome

(2009) N. Dani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions

(2008) Tomoko Kubori et al.   MOLECULAR MICROBIOLOGY