Noninvasive proteomic biomarkers for alcohol-related liver disease

Dynamic human liver proteome atlas reveals functional insights into disease pathways

(2022) Lili Niu et al.   Molecular Systems Biology

PRO‐C3 and ADAPT algorithm accurately identify patients with advanced fibrosis due to alcohol‐related liver disease

(2021) Bjørn S. Madsen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Progressive alcohol‐related liver fibrosis is characterised by imbalanced collagen formation and degradation

(2021) Maja Thiele et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Population screening for liver fibrosis: towards early diagnosis and intervention for chronic liver diseases

(2021) Pere Ginès et al.   HEPATOLOGY

Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease

(2021) Ditlev Nytoft Rasmussen et al.   JOURNAL OF HEPATOLOGY

Development and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease

(2021) Carolin Lackner et al.   JOURNAL OF HEPATOLOGY

The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

(2021) Tom H Karlsen et al.   LANCET

Proteomic screening of plasma identifies potential noninvasive biomarkers associated with significant/advanced fibrosis in patients with nonalcoholic fatty liver disease

(2020) Wei Hou et al.   BIOSCIENCE REPORTS

Association Between Fibrosis Stage and Outcomes of Patients with Non-Alcoholic Fatty Liver Disease: a Systematic Review and Meta-Analysis

(2020) Rod S. Taylor et al.   GASTROENTEROLOGY

Monitoring protein communities and their responses to therapeutics

(2020) Hanna G. Budayeva et al.   NATURE REVIEWS DRUG DISCOVERY

Biomarker discovery for chronic liver diseases by multi-omics – a preclinical case study

(2020) Daniel Veyel et al.   Scientific Reports

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

(2020) Naeimeh Atabaki-Pasdar et al.   PLOS MEDICINE

Projected prevalence and mortality associated with alcohol-related liver disease in the USA, 2019–40: a modelling study

(2020) Jovan Julien et al.   Lancet Public Health

Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis

(2020) Mads Israelsen et al.   Clinical Gastroenterology and Hepatology

Plasma proteome profiling discovers novel proteins associated with non‐alcoholic fatty liver disease

(2019) Lili Niu et al.   Molecular Systems Biology

MaxQuant.Live enables global targeting of more than 25,000 peptides

(2019) Christoph Wichmann et al.   MOLECULAR & CELLULAR PROTEOMICS

Clinical course and mortality by etiology of liver cirrhosis in Sweden: a population based, long-term follow-up study of 1317 patients

(2019) Emma Nilsson et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Role of Both Protein C and Antithrombin III as Predictors of stage of liver disease in Chronic Viral Hepatitis B or C Infected patients

(2019) Amany Mohamed Abo-Elenein et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Contemporary Epidemiology of Chronic Liver Disease and Cirrhosis

(2019) Andrew M. Moon et al.   Clinical Gastroenterology and Hepatology

Cost‐effectiveness of non‐invasive screening for alcohol‐related liver fibrosis

(2019) Lars Asphaug et al.   HEPATOLOGY

FABP4 and MMP9 levels identified as predictive factors for poor prognosis in patients with nonalcoholic fatty liver using data mining approaches and gene expression analysis

(2019) Audrey Coilly et al.   Scientific Reports

Accuracy of the Enhanced Liver Fibrosis Test vs FibroTest, Elastography, and Indirect Markers in Detection of Advanced Fibrosis in Patients With Alcoholic Liver Disease

(2018) Maja Thiele et al.   GASTROENTEROLOGY

Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policies

(2018) Laura Pimpin et al.   JOURNAL OF HEPATOLOGY

Progress in non-invasive detection of liver fibrosis

(2018) Li Chengxi et al.   Cancer Biology & Medicine

Afamin and adropin in patients with alcohol-induced liver cirrhosis

(2018) Andrzej Prystupa et al.   ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE

A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics

(2018) Nicolai Bache et al.   MOLECULAR & CELLULAR PROTEOMICS

Mechanisms of hepatic stellate cell activation

(2017) Takuma Tsuchida et al.   Nature Reviews Gastroenterology & Hepatology

A multi-component classifier for nonalcoholic fatty liver disease (NAFLD) based on genomic, proteomic and phenomic data domains

(2017) G. Craig Wood et al.   Scientific Reports

Phase-Constrained Spectrum Deconvolution for Fourier Transform Mass Spectrometry

(2016) Dmitry Grinfeld et al.   ANALYTICAL CHEMISTRY

Transient and 2-Dimensional Shear-Wave Elastography Provide Comparable Assessment of Alcoholic Liver Fibrosis and Cirrhosis

(2016) Maja Thiele et al.   GASTROENTEROLOGY

Alcohol and liver disease in Europe – Simple measures have the potential to prevent tens of thousands of premature deaths

(2016) Nick Sheron   JOURNAL OF HEPATOLOGY

Mass-spectrometric exploration of proteome structure and function

(2016) Ruedi Aebersold et al.   NATURE

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

Non-alcoholic fatty liver disease (NAFLD): summary of NICE guidance

(2016) Jessica Glen et al.   BMJ-British Medical Journal

Non-alcoholic fatty liver disease (NAFLD): summary of NICE guidance

(2016) Jessica Glen et al.   BMJ-British Medical Journal

Plasma Proteome Profiling to Assess Human Health and Disease

(2016) Philipp E. Geyer et al.   Cell Systems

Novel insights into the function and dynamics of extracellular matrix in liver fibrosis

(2015) Morten A. Karsdal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Extending the Limits of Quantitative Proteome Profiling with Data-Independent Acquisition and Application to Acetaminophen-Treated Three-Dimensional Liver Microtissues

(2015) Roland Bruderer et al.   MOLECULAR & CELLULAR PROTEOMICS

Rapid mass spectrometric conversion of tissue biopsy samples into permanent quantitative digital proteome maps

(2015) Tiannan Guo et al.   NATURE MEDICINE

Tenascins in fibrotic disorders—from bench to bedside

(2015) M Kasprzycka et al.   Cell Adhesion & Migration

Validity of noninvasive markers of methotrexate-induced hepatotoxicity: a retrospective cohort study

(2014) C.L. Martyn-Simmons et al.   BRITISH JOURNAL OF DERMATOLOGY

The human liver-specific proteome defined by transcriptomics and antibody-based profiling

(2014) Caroline Kampf et al.   FASEB JOURNAL

Advancing the High Throughput Identification of Liver Fibrosis Protein Signatures Using Multiplexed Ion Mobility Spectrometry

(2014) Erin Shammel Baker et al.   MOLECULAR & CELLULAR PROTEOMICS

Next-generation proteomics: towards an integrative view of proteome dynamics

(2012) A. F. Maarten Altelaar et al.   NATURE REVIEWS GENETICS

Discovery of Novel Biomarker Candidates for Liver Fibrosis in Hepatitis C Patients: A Preliminary Study

(2012) Bevin Gangadharan et al.   PLoS One

Galectin-3-binding protein: a serological and histological assessment in accordance with hepatitis C-related liver fibrosis

(2010) Kin Jip Cheung et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: A multicenter validation study

(2009) Ariel E. Feldstein et al.   HEPATOLOGY

Insulin-like growth factor binding protein-7 induces activation and transdifferentiation of hepatic stellate cells in vitro

(2009) Li-Xin Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY